(13 nodes) (2020) Changes in Nkx2.1, Sox2, Bmp4, and Bmp16 expression underlying the lung-to-gas bladder evolutionary transition in ray-finned fishes. network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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white nodes:
second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

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Others

textmining

co-expression

protein homology

Your Input:
	TGFB2	Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
	SMAD5	Mothers against decapentaplegic homolog. (467 aa)
	TGFB1	Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
	BARX1	BARX homeobox 1. (250 aa)
	LOC102352268	Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
	TGFB3	Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
	BMP2	Bone morphogenetic protein 2. (402 aa)
	PXDN	Peroxidasin. (1149 aa)
	SMAD1	Mothers against decapentaplegic homolog. (465 aa)
	BMP4	Bone morphogenetic protein 4. (460 aa)
	PXDNL	Peroxidasin like. (1276 aa)
	LOC102351081	Bone morphogenetic protein 16. (396 aa)
	SOX2	SRY-box transcription factor 2. (315 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BARX1	BMP4	ENSLACP00000019934	ENSLACP00000021723	BARX homeobox 1.	Bone morphogenetic protein 4.	0.477
BMP2	BMP4	ENSLACP00000016168	ENSLACP00000021723	Bone morphogenetic protein 2.	Bone morphogenetic protein 4.	0.903
BMP2	SMAD1	ENSLACP00000016168	ENSLACP00000012771	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.739
BMP2	SMAD5	ENSLACP00000016168	ENSLACP00000008275	Bone morphogenetic protein 2.	Mothers against decapentaplegic homolog.	0.613
BMP4	BARX1	ENSLACP00000021723	ENSLACP00000019934	Bone morphogenetic protein 4.	BARX homeobox 1.	0.477
BMP4	BMP2	ENSLACP00000021723	ENSLACP00000016168	Bone morphogenetic protein 4.	Bone morphogenetic protein 2.	0.903
BMP4	SMAD1	ENSLACP00000021723	ENSLACP00000012771	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.745
BMP4	SMAD5	ENSLACP00000021723	ENSLACP00000008275	Bone morphogenetic protein 4.	Mothers against decapentaplegic homolog.	0.773
BMP4	SOX2	ENSLACP00000021723	ENSLACP00000007400	Bone morphogenetic protein 4.	SRY-box transcription factor 2.	0.477
LOC102351081	SMAD1	ENSLACP00000009064	ENSLACP00000012771	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.866
LOC102351081	SMAD5	ENSLACP00000009064	ENSLACP00000008275	Bone morphogenetic protein 16.	Mothers against decapentaplegic homolog.	0.731
LOC102352268	TGFB1	ENSLACP00000019574	ENSLACP00000020652	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.693
LOC102352268	TGFB2	ENSLACP00000019574	ENSLACP00000007733	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.901
LOC102352268	TGFB3	ENSLACP00000019574	ENSLACP00000018912	Transforming growth factor beta; Belongs to the TGF-beta family.	Transforming growth factor beta; Belongs to the TGF-beta family.	0.964
PXDN	PXDNL	ENSLACP00000014158	ENSLACP00000022207	Peroxidasin.	Peroxidasin like.	0.477
PXDNL	PXDN	ENSLACP00000022207	ENSLACP00000014158	Peroxidasin like.	Peroxidasin.	0.477
SMAD1	BMP2	ENSLACP00000012771	ENSLACP00000016168	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 2.	0.739
SMAD1	BMP4	ENSLACP00000012771	ENSLACP00000021723	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 4.	0.745
SMAD1	LOC102351081	ENSLACP00000012771	ENSLACP00000009064	Mothers against decapentaplegic homolog.	Bone morphogenetic protein 16.	0.866
SMAD1	SMAD5	ENSLACP00000012771	ENSLACP00000008275	Mothers against decapentaplegic homolog.	Mothers against decapentaplegic homolog.	0.980