STRINGSTRING
MAP3K5 MAP3K5 IRAK3 IRAK3 CASP10 CASP10 TRAF6 TRAF6 CFB CFB C1R C1R ATF4 ATF4 RIPK2 RIPK2 IL1R2 IL1R2 LOC102348541 LOC102348541 LOC102351732 LOC102351732 CCR9 CCR9 CHUK CHUK CASP3 CASP3 STAT1 STAT1 RAF1 RAF1 IL17F IL17F GNAI1 GNAI1 PRSS23 PRSS23 SOCS1 SOCS1 TRAF7 TRAF7 CXCL12 CXCL12 NOD2 NOD2 MAP3K8 MAP3K8 CXCR4 CXCR4 LOC102360670 LOC102360670 LOC102361424 LOC102361424 STAT3 STAT3 NAIP NAIP LOC102367521 LOC102367521 CCR7 CCR7 TRAF1 TRAF1 LOC102363742 LOC102363742 H3B3L3_LATCH H3B3L3_LATCH NOD1 NOD1 LOC102354780 LOC102354780 TRAF5 TRAF5 TRADD TRADD JUND JUND IRAK4 IRAK4 PRSS35 PRSS35 MYD88 MYD88 MASP2 MASP2 MYC MYC SOCS3 SOCS3 GNAI3 GNAI3 HRAS HRAS NRAS NRAS STAT2 STAT2 LOC102351715 LOC102351715 C1S C1S CASP7 CASP7 KRAS KRAS
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MAP3K5Mitogen-activated protein kinase kinase kinase 5. (1171 aa)
IRAK3Interleukin 1 receptor associated kinase 3. (546 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
CFBUncharacterized protein; Belongs to the peptidase S1 family. (764 aa)
C1RComplement C1r; Belongs to the peptidase S1 family. (685 aa)
ATF4Activating transcription factor 4. (374 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (567 aa)
IL1R2Interleukin 1 receptor type 2. (378 aa)
LOC102348541Chemokine (C-X-C motif) receptor 1; Belongs to the G-protein coupled receptor 1 family. (353 aa)
LOC102351732Uncharacterized protein. (192 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (700 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
STAT1Signal transducer and activator of transcription. (1179 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
IL17FInterleukin 17F. (166 aa)
GNAI1G protein subunit alpha i1. (326 aa)
PRSS23Serine protease; Belongs to the peptidase S1B family. (382 aa)
SOCS1Suppressor of cytokine signaling 1a. (190 aa)
TRAF7TNF receptor associated factor 7. (671 aa)
CXCL12C-X-C motif chemokine ligand 12; Belongs to the intercrine alpha (chemokine CxC) family. (95 aa)
NOD2Nucleotide binding oligomerization domain containing 2. (854 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (477 aa)
CXCR4C-X-C motif chemokine receptor 4; Belongs to the G-protein coupled receptor 1 family. (363 aa)
LOC102360670Uncharacterized protein. (209 aa)
LOC102361424Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 2a. (355 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
NAIPNLR family apoptosis inhibitory protein. (1422 aa)
LOC102367521Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
CCR7C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
TRAF1TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (565 aa)
LOC102363742Uncharacterized protein; Belongs to the peptidase C14A family. (394 aa)
H3B3L3_LATCHNACHT domain-containing protein. (837 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (830 aa)
LOC102354780Serine protease; Belongs to the peptidase S1B family. (370 aa)
TRAF5TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)
TRADDDeath domain-containing protein. (313 aa)
JUNDBZIP domain-containing protein. (293 aa)
IRAK4Interleukin 1 receptor associated kinase 4. (454 aa)
PRSS35Serine protease; Belongs to the peptidase S1B family. (379 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
MASP2Mannan binding lectin serine peptidase 2; Belongs to the peptidase S1 family. (557 aa)
MYCTranscriptional regulator; Transcription factor that binds DNA in a non-specific manner, yet also specifically recognizes the core sequence 5'-CAC[GA]TG-3'. Activates the transcription of growth-related genes. (412 aa)
SOCS3Suppressor of cytokine signaling 3. (205 aa)
GNAI3Guanine nucleotide binding protein (G protein), alpha inhibiting activity polypeptide 3. (354 aa)
HRASHRas proto-oncogene, GTPase. (193 aa)
NRASNRAS proto-oncogene, GTPase. (189 aa)
STAT2Signal transducer and activator of transcription. (765 aa)
LOC102351715Uncharacterized protein. (1426 aa)
C1SComplement C1s; Belongs to the peptidase S1 family. (682 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (313 aa)
KRASKRAS proto-oncogene, GTPase. (189 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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