STRINGSTRING
GPX8 GPX8 HMOX1 HMOX1 NOS2 NOS2 GPX3 GPX3 GPX1 GPX1 LOC102346019 LOC102346019 MTOR MTOR H3B8U3_LATCH H3B8U3_LATCH SOD2 SOD2 LDLR LDLR IRS1 IRS1 H3B037_LATCH H3B037_LATCH BDNF BDNF GPX7 GPX7 INSR INSR PPARG PPARG IL6 IL6 CD36 CD36 CASP3 CASP3 IL10 IL10 LOC102358202 LOC102358202 SREBF2 SREBF2 ADIPOQ ADIPOQ
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
GPX8Glutathione peroxidase; Belongs to the glutathione peroxidase family. (173 aa)
HMOX1Heme oxygenase 1. (300 aa)
NOS2Nitric oxide synthase; Produces nitric oxide (NO). (1126 aa)
GPX3Glutathione peroxidase 3. (108 aa)
GPX1Glutathione peroxidase; Belongs to the glutathione peroxidase family. (142 aa)
LOC102346019C1q domain-containing protein. (226 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
SOD2Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (223 aa)
LDLRLow density lipoprotein receptor. (851 aa)
IRS1Insulin receptor substrate 1. (1076 aa)
H3B037_LATCHGlutathione peroxidase; Belongs to the glutathione peroxidase family. (112 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (254 aa)
GPX7Glutathione peroxidase; Belongs to the glutathione peroxidase family. (185 aa)
INSRUncharacterized protein. (270 aa)
PPARGPeroxisome proliferator-activated receptor gamma; Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut ho [...] (403 aa)
IL6Uncharacterized protein. (149 aa)
CD36CD36 molecule; Belongs to the CD36 family. (468 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
IL10Interleukin 10. (185 aa)
LOC102358202Tyrosine-protein kinase receptor. (838 aa)
SREBF2Sterol regulatory element binding transcription factor 2. (1083 aa)
ADIPOQAdiponectin, C1Q and collagen domain containing. (259 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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