STRINGSTRING
H3ACE0_LATCH H3ACE0_LATCH GAPDHS GAPDHS TRAF6 TRAF6 ADPGK ADPGK HK3 HK3 IL18 IL18 ATP6 ATP6 HIF1A HIF1A XPO1 XPO1 LOC106701779 LOC106701779 LOC102363742 LOC102363742 SOD1 SOD1 GCK GCK SQSTM1 SQSTM1 STAT3 STAT3 GAPDH GAPDH
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H3ACE0_LATCHInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
GAPDHSGlyceraldehyde-3-phosphate dehydrogenase. (396 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
ADPGKADP dependent glucokinase. (479 aa)
HK3Hexokinase 3. (908 aa)
IL18Uncharacterized protein. (200 aa)
ATP6ATP synthase subunit a; Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subuni [...] (220 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (813 aa)
XPO1Exportin 1. (1078 aa)
LOC106701779Uncharacterized protein. (373 aa)
LOC102363742Uncharacterized protein; Belongs to the peptidase C14A family. (394 aa)
SOD1Superoxide dismutase [Cu-Zn]; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the Cu-Zn superoxide dismutase family. (154 aa)
GCKPhosphotransferase. (400 aa)
SQSTM1Sequestosome 1. (441 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (16%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.