STRINGSTRING
CYP17A1 CYP17A1 BMP4 BMP4 DHH DHH SOX9 SOX9 LHX1 LHX1 PAX2 PAX2 WT1 WT1 CYP26B1 CYP26B1 WNT4 WNT4 DMRT1 DMRT1 FST FST FOXL2 FOXL2 SHH SHH CBR4 CBR4 CYP19A1 CYP19A1 DDX54 DDX54 AMH AMH KDM6B KDM6B FGFR2 FGFR2 GATA4 GATA4 OSR1 OSR1 PITX2 PITX2 TCF21 TCF21 ACTA2 ACTA2 POSTN POSTN DAZL DAZL EIF4A3 EIF4A3
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CYP17A1Cytochrome P450 family 17 subfamily A member 1; Belongs to the cytochrome P450 family. (514 aa)
BMP4Bone morphogenetic protein 4. (460 aa)
DHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (424 aa)
SOX9SRY-box transcription factor 9. (475 aa)
LHX1LIM homeobox 1. (406 aa)
PAX2Paired box 2. (456 aa)
WT1WT1 transcription factor. (422 aa)
CYP26B1Cytochrome P450 family 26 subfamily B member 1; Belongs to the cytochrome P450 family. (511 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (370 aa)
FSTFollistatin. (319 aa)
FOXL2Forkhead box L2. (305 aa)
SHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (421 aa)
CBR4Carbonyl reductase 4. (237 aa)
CYP19A1Cytochrome P450 family 19 subfamily A member 1. (443 aa)
DDX54ATP-dependent RNA helicase; Belongs to the DEAD box helicase family. DDX54/DBP10 subfamily. (891 aa)
AMHAnti-Mullerian hormone. (562 aa)
KDM6BLysine demethylase 6B. (1638 aa)
FGFR2Fibroblast growth factor receptor. (810 aa)
GATA4GATA binding protein 4. (402 aa)
OSR1Odd-skipped related transcription factor 1. (259 aa)
PITX2Homeobox protein. (314 aa)
TCF21Transcription factor 21. (179 aa)
ACTA2Uncharacterized protein. (338 aa)
POSTNPeriostin. (673 aa)
DAZLRRM domain-containing protein. (300 aa)
EIF4A3Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family. (406 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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