STRINGSTRING
LOC102358202 LOC102358202 YWHAZ YWHAZ H3A2B0_LATCH H3A2B0_LATCH LOC102356182 LOC102356182 H3ACE0_LATCH H3ACE0_LATCH TGFB2 TGFB2 FGF8 FGF8 FGF11 FGF11 INSR INSR FGF16 FGF16 FGF22 FGF22 FGF13 FGF13 FGF3 FGF3 LOC102357450 LOC102357450 FGF4 FGF4 TLR2 TLR2 FGF19 FGF19 FGF20 FGF20 FGF1 FGF1 FGF18 FGF18 IRS1 IRS1 FGF7 FGF7 FGF5 FGF5 MSTN MSTN H3B8U3_LATCH H3B8U3_LATCH FGF14 FGF14 MTOR MTOR TGFB3 TGFB3 MYD88 MYD88 FGF2 FGF2 LOC102352268 LOC102352268 FGF12 FGF12 AKT1S1 AKT1S1 FGF6 FGF6 TGFB1 TGFB1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102358202Tyrosine-protein kinase receptor. (838 aa)
YWHAZ14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa)
H3A2B0_LATCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
H3ACE0_LATCHInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
INSRUncharacterized protein. (270 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
LOC102357450Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (798 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
IRS1Insulin receptor substrate 1. (1076 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
MSTNMyostatin. (372 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
AKT1S1AKT1 substrate 1. (285 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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