(7 nodes) (2021) Effect of Cyclic Heat Stress on Feeding-Related Hypothalamic Neuropeptides of Three Broiler Populations and Their Ancestor Jungle Fowl. network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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Your Input:
	ADIPOQ	Adiponectin, C1Q and collagen domain containing. (259 aa)
	MC4R	Melanocortin 4 receptor. (329 aa)
	NPY	Neuropeptide Y. (100 aa)
	LEP	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
	POMC	Proopiomelanocortin. (255 aa)
	GHSR	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family. (367 aa)
	LOC102346019	C1q domain-containing protein. (226 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADIPOQ	LEP	ENSLACP00000000452	ENSLACP00000011398	Adiponectin, C1Q and collagen domain containing.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.952
ADIPOQ	LOC102346019	ENSLACP00000000452	ENSLACP00000019134	Adiponectin, C1Q and collagen domain containing.	C1q domain-containing protein.	0.904
ADIPOQ	POMC	ENSLACP00000000452	ENSLACP00000013290	Adiponectin, C1Q and collagen domain containing.	Proopiomelanocortin.	0.465
GHSR	LEP	ENSLACP00000015758	ENSLACP00000011398	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.490
GHSR	NPY	ENSLACP00000015758	ENSLACP00000002115	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Neuropeptide Y.	0.567
GHSR	POMC	ENSLACP00000015758	ENSLACP00000013290	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	Proopiomelanocortin.	0.694
LEP	ADIPOQ	ENSLACP00000011398	ENSLACP00000000452	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Adiponectin, C1Q and collagen domain containing.	0.952
LEP	GHSR	ENSLACP00000011398	ENSLACP00000015758	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.490
LEP	LOC102346019	ENSLACP00000011398	ENSLACP00000019134	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	C1q domain-containing protein.	0.917
LEP	MC4R	ENSLACP00000011398	ENSLACP00000000487	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Melanocortin 4 receptor.	0.745
LEP	NPY	ENSLACP00000011398	ENSLACP00000002115	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Neuropeptide Y.	0.821
LEP	POMC	ENSLACP00000011398	ENSLACP00000013290	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	Proopiomelanocortin.	0.808
LOC102346019	ADIPOQ	ENSLACP00000019134	ENSLACP00000000452	C1q domain-containing protein.	Adiponectin, C1Q and collagen domain containing.	0.904
LOC102346019	LEP	ENSLACP00000019134	ENSLACP00000011398	C1q domain-containing protein.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.917
LOC102346019	POMC	ENSLACP00000019134	ENSLACP00000013290	C1q domain-containing protein.	Proopiomelanocortin.	0.456
MC4R	LEP	ENSLACP00000000487	ENSLACP00000011398	Melanocortin 4 receptor.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.745
MC4R	NPY	ENSLACP00000000487	ENSLACP00000002115	Melanocortin 4 receptor.	Neuropeptide Y.	0.788
MC4R	POMC	ENSLACP00000000487	ENSLACP00000013290	Melanocortin 4 receptor.	Proopiomelanocortin.	0.999
NPY	GHSR	ENSLACP00000002115	ENSLACP00000015758	Neuropeptide Y.	Growth hormone secretagogue receptor; Belongs to the G-protein coupled receptor 1 family.	0.567
NPY	LEP	ENSLACP00000002115	ENSLACP00000011398	Neuropeptide Y.	Leptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family.	0.821