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LOC102367296 LOC102367296 ALDH1A2 ALDH1A2 PAH PAH LOC102362664 LOC102362664 FOXP2 FOXP2 SP7 SP7 NUBP2 NUBP2 SPOCK3 SPOCK3 FOXF1 FOXF1 EMX2 EMX2 POU3F3 POU3F3 MEIS2 MEIS2 BARX1 BARX1 SOX6 SOX6 NR5A2 NR5A2 HYAL4 HYAL4 FOXP2-2 FOXP2-2 DLX5 DLX5 FOXF2 FOXF2 GATA3 GATA3 KLF4 KLF4 PITX1 PITX1 HAND2 HAND2 SOX10 SOX10 ACTA2 ACTA2 JUN JUN LEF1 LEF1 EGR1 EGR1 WNT5A WNT5A IRF8 IRF8 CEBPA CEBPA FOXC1 FOXC1 SOX2 SOX2 ETS2 ETS2 FOXP4 FOXP4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102367296Nuclear receptor subfamily 2, group F, member 5. (396 aa)
ALDH1A2Aldehyde dehydrogenase 1 family member A2; Belongs to the aldehyde dehydrogenase family. (497 aa)
PAHPhenylalanine hydroxylase. (335 aa)
LOC102362664POU domain protein. (452 aa)
FOXP2Forkhead box P2. (604 aa)
SP7Sp7 transcription factor. (431 aa)
NUBP2Cytosolic Fe-S cluster assembly factor NUBP2; Component of the cytosolic iron-sulfur (Fe/S) protein assembly (CIA) machinery. Required for maturation of extramitochondrial Fe-S proteins. The NUBP1-NUBP2 heterotetramer forms a Fe-S scaffold complex, mediating the de novo assembly of an Fe-S cluster and its transfer to target apoproteins; Belongs to the Mrp/NBP35 ATP-binding proteins family. NUBP2/CFD1 subfamily. (265 aa)
SPOCK3SPARC (osteonectin), cwcv and kazal like domains proteoglycan 3. (194 aa)
FOXF1Forkhead box F1. (381 aa)
EMX2Empty spiracles homeobox 2. (247 aa)
POU3F3POU domain protein. (428 aa)
MEIS2Meis homeobox 2. (477 aa)
BARX1BARX homeobox 1. (250 aa)
SOX6SRY-box transcription factor 6. (814 aa)
NR5A2Nuclear receptor subfamily 5 group A member 2. (394 aa)
HYAL4Hyaluronidase. (483 aa)
FOXP2-2Uncharacterized protein. (66 aa)
DLX5Distal-less homeobox 5. (290 aa)
FOXF2Forkhead box F2a. (379 aa)
GATA3GATA binding protein 3. (447 aa)
KLF4Kruppel like factor 4. (429 aa)
PITX1Homeobox protein. (305 aa)
HAND2Heart and neural crest derivatives expressed 2. (210 aa)
SOX10SRY-box transcription factor 10. (451 aa)
ACTA2Uncharacterized protein. (338 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
EGR1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (505 aa)
WNT5AProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (381 aa)
IRF8Interferon regulatory factor 8. (430 aa)
CEBPACCAAT/enhancer-binding protein. (299 aa)
FOXC1Forkhead box C1. (471 aa)
SOX2SRY-box transcription factor 2. (315 aa)
ETS2ETS proto-oncogene 2, transcription factor; Transcription factor; Belongs to the ETS family. (470 aa)
FOXP4Forkhead box P4. (465 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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