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TMPRSS2 TMPRSS2 FURIN FURIN ACE2 ACE2 TBK1 TBK1 CLTRN CLTRN LOC102358151 LOC102358151 KDM5B KDM5B TLR3 TLR3 H3ANL8_LATCH H3ANL8_LATCH TLL1 TLL1 CXCR6 CXCR6 IL6 IL6 CTSB CTSB TFRC TFRC STAT1 STAT1 REN REN REXO2 REXO2 DPP9 DPP9 CADM1 CADM1 STAT2 STAT2 IL18 IL18 ZBTB16 ZBTB16 TICAM1 TICAM1 MYD88 MYD88 IRF3 IRF3 TLR8 TLR8 CCR9 CCR9 IL10 IL10 TLR7 TLR7 IFNAR1 IFNAR1 SLC6A20 SLC6A20 DDR1 DDR1 IRF1 IRF1 CTSC CTSC LZTFL1 LZTFL1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TMPRSS2Transmembrane serine protease 2; Belongs to the peptidase S1 family. (487 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (801 aa)
ACE2Angiotensin-converting enzyme. (814 aa)
TBK1TANK binding kinase 1. (675 aa)
CLTRNCollectrin domain-containing protein. (226 aa)
LOC102358151Angiotensin-converting enzyme. (1260 aa)
KDM5BLysine demethylase 5B. (1659 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (766 aa)
H3ANL8_LATCHFibroblast activation protein, alpha; Belongs to the peptidase S9B family. (755 aa)
TLL1Tolloid like 1. (667 aa)
CXCR6C-X-C motif chemokine receptor 6; Belongs to the G-protein coupled receptor 1 family. (350 aa)
IL6Uncharacterized protein. (149 aa)
CTSBCathepsin B; Belongs to the peptidase C1 family. (344 aa)
TFRCTransferrin receptor. (778 aa)
STAT1Signal transducer and activator of transcription. (1179 aa)
RENRenin; Belongs to the peptidase A1 family. (374 aa)
REXO2RNA exonuclease 2. (243 aa)
DPP9Dipeptidyl peptidase 9; Belongs to the peptidase S9B family. (889 aa)
CADM1Uncharacterized protein. (321 aa)
STAT2Signal transducer and activator of transcription. (765 aa)
IL18Uncharacterized protein. (200 aa)
ZBTB16Zinc finger and BTB domain containing 16. (420 aa)
TICAM1TRIF-NTD domain-containing protein. (705 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
IRF3Interferon regulatory factor 3. (481 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1016 aa)
CCR9C-C motif chemokine receptor 9; Belongs to the G-protein coupled receptor 1 family. (369 aa)
IL10Interleukin 10. (185 aa)
TLR7Toll-like receptor 7. (1033 aa)
IFNAR1Uncharacterized protein. (548 aa)
SLC6A20Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (593 aa)
DDR1Discoidin domain receptor tyrosine kinase 1. (964 aa)
IRF1Interferon regulatory factor. (264 aa)
CTSCCathepsin C; Belongs to the peptidase C1 family. (461 aa)
LZTFL1Leucine zipper transcription factor like 1. (263 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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