STRINGSTRING
SC5D SC5D NPY NPY TNFSF12 TNFSF12 CFTR CFTR CYP51A1 CYP51A1 SLC6A8 SLC6A8 EDAR EDAR DHCR24 DHCR24 AQP4 AQP4 H3AHQ6_LATCH H3AHQ6_LATCH SLC25A48 SLC25A48 WNT4 WNT4 NSDHL NSDHL SQLE SQLE DHCR7 DHCR7 H3B8U3_LATCH H3B8U3_LATCH MTOR MTOR SLC44A4 SLC44A4 SLC37A4 SLC37A4
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SC5DSterol-C5-desaturase; Belongs to the sterol desaturase family. (299 aa)
NPYNeuropeptide Y. (100 aa)
TNFSF12TNF superfamily member 12; Belongs to the tumor necrosis factor family. (246 aa)
CFTRCystic fibrosis transmembrane conductance regulator; Epithelial ion channel that plays an important role in the regulation of epithelial ion and water transport and fluid homeostasis. Mediates the transport of chloride ions across the cell membrane. Channel activity is coupled to ATP hydrolysis. The ion channel is also permeable to HCO(3-); selectivity depends on the extracellular chloride concentration. Exerts its function also by modulating the activity of other ion channels and transporters. Contributes to the regulation of the pH and the ion content of the epithelial fluid layer. (1491 aa)
CYP51A1Cytochrome P450 family 51 subfamily A member 1; Belongs to the cytochrome P450 family. (508 aa)
SLC6A8Transporter; Belongs to the sodium:neurotransmitter symporter (SNF) (TC 2.A.22) family. (641 aa)
EDAREctodysplasin A receptor. (454 aa)
DHCR2424-dehydrocholesterol reductase. (516 aa)
AQP4Aquaporin 4; Belongs to the MIP/aquaporin (TC 1.A.8) family. (319 aa)
H3AHQ6_LATCHEBP cholestenol delta-isomerase. (131 aa)
SLC25A48Solute carrier family 25 member 48; Belongs to the mitochondrial carrier (TC 2.A.29) family. (284 aa)
WNT4Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
NSDHLNAD(P) dependent steroid dehydrogenase-like; Belongs to the 3-beta-HSD family. (340 aa)
SQLESE domain-containing protein. (506 aa)
DHCR77-dehydrocholesterol reductase. (478 aa)
H3B8U3_LATCHSerine/threonine-protein kinase TOR. (1418 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
SLC44A4Solute carrier family 44 member 4; Belongs to the CTL (choline transporter-like) family. (470 aa)
SLC37A4Solute carrier family 37 member 4. (441 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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