(7 nodes) (2022) What Do In Vitro and In Vivo Models Tell Us about Anisakiasis? New Tools Still to Be Explored. network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	IL10	Interleukin 10. (185 aa)
	CASP3	Caspase 3; Belongs to the peptidase C14A family. (290 aa)
	IL6	Uncharacterized protein. (149 aa)
	LOC102357450	Uncharacterized protein; Belongs to the heat shock protein 70 family. (641 aa)
	TLR2	Toll like receptor 2; Belongs to the Toll-like receptor family. (798 aa)
	CCR7	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family. (379 aa)
	DUSP1	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (368 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP3	IL10	ENSLACP00000007386	ENSLACP00000005382	Caspase 3; Belongs to the peptidase C14A family.	Interleukin 10.	0.541
CASP3	IL6	ENSLACP00000007386	ENSLACP00000009318	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein.	0.699
CASP3	LOC102357450	ENSLACP00000007386	ENSLACP00000014115	Caspase 3; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.423
CCR7	IL10	ENSLACP00000015163	ENSLACP00000005382	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Interleukin 10.	0.573
CCR7	IL6	ENSLACP00000015163	ENSLACP00000009318	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	Uncharacterized protein.	0.572
IL10	CASP3	ENSLACP00000005382	ENSLACP00000007386	Interleukin 10.	Caspase 3; Belongs to the peptidase C14A family.	0.541
IL10	CCR7	ENSLACP00000005382	ENSLACP00000015163	Interleukin 10.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.573
IL10	IL6	ENSLACP00000005382	ENSLACP00000009318	Interleukin 10.	Uncharacterized protein.	0.957
IL10	TLR2	ENSLACP00000005382	ENSLACP00000014305	Interleukin 10.	Toll like receptor 2; Belongs to the Toll-like receptor family.	0.667
IL6	CASP3	ENSLACP00000009318	ENSLACP00000007386	Uncharacterized protein.	Caspase 3; Belongs to the peptidase C14A family.	0.699
IL6	CCR7	ENSLACP00000009318	ENSLACP00000015163	Uncharacterized protein.	C-C motif chemokine receptor 7; Belongs to the G-protein coupled receptor 1 family.	0.572
IL6	IL10	ENSLACP00000009318	ENSLACP00000005382	Uncharacterized protein.	Interleukin 10.	0.957
IL6	TLR2	ENSLACP00000009318	ENSLACP00000014305	Uncharacterized protein.	Toll like receptor 2; Belongs to the Toll-like receptor family.	0.608
LOC102357450	CASP3	ENSLACP00000014115	ENSLACP00000007386	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Caspase 3; Belongs to the peptidase C14A family.	0.423
LOC102357450	TLR2	ENSLACP00000014115	ENSLACP00000014305	Uncharacterized protein; Belongs to the heat shock protein 70 family.	Toll like receptor 2; Belongs to the Toll-like receptor family.	0.649
TLR2	IL10	ENSLACP00000014305	ENSLACP00000005382	Toll like receptor 2; Belongs to the Toll-like receptor family.	Interleukin 10.	0.667
TLR2	IL6	ENSLACP00000014305	ENSLACP00000009318	Toll like receptor 2; Belongs to the Toll-like receptor family.	Uncharacterized protein.	0.608
TLR2	LOC102357450	ENSLACP00000014305	ENSLACP00000014115	Toll like receptor 2; Belongs to the Toll-like receptor family.	Uncharacterized protein; Belongs to the heat shock protein 70 family.	0.649