(15 nodes) (2022) Paleoproteomics. network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC102347143	Uncharacterized protein. (612 aa)
	LOC102359827	Uncharacterized protein. (536 aa)
	LOC102363505	Zgc:136461; Belongs to the peptidase S1 family. (227 aa)
	COL1A2	Collagen type I alpha 2 chain. (1367 aa)
	LUM	Lumican. (345 aa)
	F10	Coagulation factor X. (475 aa)
	CHAD	Chondroadherin. (361 aa)
	H3BCB7_LATCH	Uncharacterized protein; Belongs to the peptidase S1 family. (463 aa)
	PROC	Uncharacterized protein. (444 aa)
	F2	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family. (618 aa)
	BGN	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (371 aa)
	COL1A1	Collagen type I alpha 1 chain. (1486 aa)
	F9	Coagulation factor IX. (453 aa)
	CRTAP	Cartilage associated protein. (422 aa)
	POSTN	Periostin. (673 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BGN	LUM	ENSLACP00000011654	ENSLACP00000001625	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	Lumican.	0.709
COL1A1	CRTAP	ENSLACP00000011991	ENSLACP00000009252	Collagen type I alpha 1 chain.	Cartilage associated protein.	0.455
CRTAP	COL1A1	ENSLACP00000009252	ENSLACP00000011991	Cartilage associated protein.	Collagen type I alpha 1 chain.	0.455
F10	F2	ENSLACP00000001289	ENSLACP00000021404	Coagulation factor X.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.822
F2	F10	ENSLACP00000021404	ENSLACP00000001289	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor X.	0.822
F2	F9	ENSLACP00000021404	ENSLACP00000012201	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Coagulation factor IX.	0.801
F2	LOC102347143	ENSLACP00000021404	ENSLACP00000004517	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.672
F2	PROC	ENSLACP00000021404	ENSLACP00000017436	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.829
F9	F2	ENSLACP00000012201	ENSLACP00000021404	Coagulation factor IX.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.801
H3BCB7_LATCH	LOC102347143	ENSLACP00000019538	ENSLACP00000004517	Uncharacterized protein; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.485
LOC102347143	F2	ENSLACP00000004517	ENSLACP00000021404	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.672
LOC102347143	H3BCB7_LATCH	ENSLACP00000004517	ENSLACP00000019538	Uncharacterized protein.	Uncharacterized protein; Belongs to the peptidase S1 family.	0.485
LOC102347143	LOC102363505	ENSLACP00000004517	ENSLACP00000002520	Uncharacterized protein.	Zgc:136461; Belongs to the peptidase S1 family.	0.485
LOC102363505	LOC102347143	ENSLACP00000002520	ENSLACP00000004517	Zgc:136461; Belongs to the peptidase S1 family.	Uncharacterized protein.	0.485
LUM	BGN	ENSLACP00000001625	ENSLACP00000011654	Lumican.	Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.	0.709
LUM	POSTN	ENSLACP00000001625	ENSLACP00000005531	Lumican.	Periostin.	0.707
POSTN	LUM	ENSLACP00000005531	ENSLACP00000001625	Periostin.	Lumican.	0.707
PROC	F2	ENSLACP00000017436	ENSLACP00000021404	Uncharacterized protein.	Prothrombin; Thrombin, which cleaves bonds after Arg and Lys, converts fibrinogen to fibrin and activates factors V, VII, VIII, XIII, and, in complex with thrombomodulin, protein C. Functions in blood homeostasis, inflammation and wound healing; Belongs to the peptidase S1 family.	0.829