STRINGSTRING
LOC102347432 LOC102347432 PXN PXN PKLR PKLR SPHK2 SPHK2 GAPDH GAPDH GRK1 GRK1 RHO RHO EDNRB EDNRB HDAC1 HDAC1 PIK3CA PIK3CA NOX1 NOX1 EDN1 EDN1 MTOR MTOR PIK3CG PIK3CG VCL VCL PKM PKM
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102347432Rhodopsin. (355 aa)
PXNPaxillin. (1112 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
SPHK2Sphingosine kinase 2. (479 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
GRK1G protein-coupled receptor kinase; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. GPRK subfamily. (566 aa)
RHORhodopsin. (355 aa)
EDNRBEndothelin receptor type B; Belongs to the G-protein coupled receptor 1 family. (440 aa)
HDAC1Histone deacetylase 1; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large multiprotein complexes. (484 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
NOX1NADPH oxidase 1. (567 aa)
EDN1Endothelin 1. (216 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
VCLVinculin. (832 aa)
PKMPyruvate kinase; Belongs to the pyruvate kinase family. (539 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.