STRINGSTRING
H3ACE0_LATCH H3ACE0_LATCH SMAD2 SMAD2 GDF9 GDF9 KiSS2 KiSS2 PAQR8 PAQR8 LHCGR LHCGR DMRT1 DMRT1 PRL PRL POMC POMC BDNF BDNF SOX9 SOX9 PYY PYY CCK CCK BMP15 BMP15
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H3ACE0_LATCHInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
SMAD2Mothers against decapentaplegic homolog. (467 aa)
GDF9Growth differentiation factor 9. (442 aa)
KiSS2Kisspeptin 2. (145 aa)
PAQR8Progestin and adipoQ receptor family member 8. (359 aa)
LHCGRLutropin-choriogonadotropic hormone receptor; Receptor for lutropin-choriogonadotropic hormone. The activity of this receptor is mediated by G proteins which activate adenylate cyclase; Belongs to the G-protein coupled receptor 1 family. FSH/LSH/TSH subfamily. (593 aa)
DMRT1Doublesex and mab-3 related transcription factor 1. (370 aa)
PRLProlactin. (231 aa)
POMCProopiomelanocortin. (255 aa)
BDNFBrain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (254 aa)
SOX9SRY-box transcription factor 9. (475 aa)
PYYPeptide YY. (97 aa)
CCKCholecystokinin. (131 aa)
BMP15Bone morphogenetic protein 15. (394 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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