(6 nodes) (2022) Editorial: Thymus function and aging: A focus on thymic epithelial cells. network (Latimeria chalumnae)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	LOC102357987	Uncharacterized protein. (2519 aa)
	EPCAM	Epithelial cell adhesion molecule. (313 aa)
	DLL1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (723 aa)
	NOTCH2	Notch receptor 2. (2489 aa)
	NOTCH1	Notch receptor 1. (2494 aa)
	DLL4	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (688 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
DLL1	DLL4	ENSLACP00000009351	ENSLACP00000013765	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.937
DLL1	LOC102357987	ENSLACP00000009351	ENSLACP00000014598	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.984
DLL1	NOTCH1	ENSLACP00000009351	ENSLACP00000020474	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1.	0.848
DLL1	NOTCH2	ENSLACP00000009351	ENSLACP00000022069	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.962
DLL4	DLL1	ENSLACP00000013765	ENSLACP00000009351	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.937
DLL4	LOC102357987	ENSLACP00000013765	ENSLACP00000014598	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Uncharacterized protein.	0.994
DLL4	NOTCH1	ENSLACP00000013765	ENSLACP00000020474	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 1.	0.951
DLL4	NOTCH2	ENSLACP00000013765	ENSLACP00000022069	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Notch receptor 2.	0.960
LOC102357987	DLL1	ENSLACP00000014598	ENSLACP00000009351	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.984
LOC102357987	DLL4	ENSLACP00000014598	ENSLACP00000013765	Uncharacterized protein.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.994
NOTCH1	DLL1	ENSLACP00000020474	ENSLACP00000009351	Notch receptor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.848
NOTCH1	DLL4	ENSLACP00000020474	ENSLACP00000013765	Notch receptor 1.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.951
NOTCH2	DLL1	ENSLACP00000022069	ENSLACP00000009351	Notch receptor 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.962
NOTCH2	DLL4	ENSLACP00000022069	ENSLACP00000013765	Notch receptor 2.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.960