STRINGSTRING
CD40 CD40 IL10 IL10 TGFB2 TGFB2 ZAP70 ZAP70 IL6 IL6 TLN1 TLN1 MRAS MRAS STAT3 STAT3 L1CAM L1CAM FYN FYN TLN2 TLN2 SEMA3A SEMA3A FURIN FURIN FES FES SEMA3B SEMA3B F5 F5 TGFB3 TGFB3 RRAS RRAS LOC102352268 LOC102352268 TGFB1 TGFB1 PGF PGF PDGFD PDGFD HGF HGF LOC102358504 LOC102358504 NRP1 NRP1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
CD40TNFR-Cys domain-containing protein. (167 aa)
IL10Interleukin 10. (185 aa)
TGFB2Transforming growth factor beta; Belongs to the TGF-beta family. (415 aa)
ZAP70Tyrosine-protein kinase. (609 aa)
IL6Uncharacterized protein. (149 aa)
TLN1Talin 1. (2546 aa)
MRASUncharacterized protein. (208 aa)
STAT3Signal transducer and activator of transcription. (763 aa)
L1CAML1 cell adhesion molecule. (1176 aa)
FYNTyrosine-protein kinase. (537 aa)
TLN2Talin 2. (1962 aa)
SEMA3ASemaphorin 3A; Belongs to the semaphorin family. (635 aa)
FURINFurin, paired basic amino acid cleaving enzyme; Belongs to the peptidase S8 family. (801 aa)
FESTyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (827 aa)
SEMA3BSemaphorin 3B; Belongs to the semaphorin family. (767 aa)
F5Coagulation factor V; Belongs to the multicopper oxidase family. (1780 aa)
TGFB3Transforming growth factor beta; Belongs to the TGF-beta family. (409 aa)
RRASRAS related. (174 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
TGFB1Transforming growth factor beta; Belongs to the TGF-beta family. (401 aa)
PGFPlacental growth factor; Belongs to the PDGF/VEGF growth factor family. (132 aa)
PDGFDPlatelet derived growth factor D; Belongs to the PDGF/VEGF growth factor family. (369 aa)
HGFHepatocyte growth factor; Potent mitogen for mature parenchymal hepatocyte cells, seems to be a hepatotrophic factor, and acts as a growth factor for a broad spectrum of tissues and cell types. Activating ligand for the receptor tyrosine kinase MET by binding to it and promoting its dimerization. Belongs to the peptidase S1 family. Plasminogen subfamily. (720 aa)
LOC102358504SCY domain-containing protein. (118 aa)
NRP1Neuropilin; Belongs to the neuropilin family. (928 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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