STRINGSTRING
FGF20 FGF20 MMP13 MMP13 MMP9 MMP9 FGF19 FGF19 FGF4 FGF4 FGF3 FGF3 FGF13 FGF13 COL1A1 COL1A1 SOST SOST FGF22 FGF22 FGF16 FGF16 PHOSPHO1 PHOSPHO1 TNFSF11 TNFSF11 FGF11 FGF11 WNT16 WNT16 FGF8 FGF8 TNFRSF11B TNFRSF11B LOC102358266 LOC102358266 IHH IHH ATF4 ATF4 H3A2B0_LATCH H3A2B0_LATCH NFATC1 NFATC1 LOC102356182 LOC102356182 CTSK CTSK SPI1 SPI1 FGF6 FGF6 SPARC SPARC FGF12 FGF12 ALPL ALPL H3BC89_LATCH H3BC89_LATCH FGF2 FGF2 FGF14 FGF14 FGF5 FGF5 CSF1R CSF1R FGF7 FGF7 FGF18 FGF18 FGF1 FGF1 SP7 SP7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
FGF20Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
MMP13Matrix metallopeptidase 13. (467 aa)
MMP9Matrix metallopeptidase 9. (682 aa)
FGF19Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
FGF4Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (195 aa)
FGF3Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (237 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
COL1A1Collagen type I alpha 1 chain. (1486 aa)
SOSTSclerostin. (210 aa)
FGF22Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (99 aa)
FGF16Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
PHOSPHO1Phosphoethanolamine/phosphocholine phosphatase. (267 aa)
TNFSF11TNF superfamily member 11; Belongs to the tumor necrosis factor family. (169 aa)
FGF11Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (246 aa)
WNT16Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (357 aa)
FGF8Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (213 aa)
TNFRSF11BTNF receptor superfamily member 11b. (409 aa)
LOC102358266Dickkopf WNT signaling pathway inhibitor 1b. (261 aa)
IHHHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (410 aa)
ATF4Activating transcription factor 4. (374 aa)
H3A2B0_LATCHFibroblast growth factor; Belongs to the heparin-binding growth factors family. (216 aa)
NFATC1Nuclear factor of activated T cells 1. (455 aa)
LOC102356182Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (196 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (333 aa)
SPI1Spi-1 proto-oncogene. (269 aa)
FGF6Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (207 aa)
SPARCSecreted protein acidic and cysteine rich. (304 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
ALPLAlkaline phosphatase. (293 aa)
H3BC89_LATCHAlkaline phosphatase, biomineralization associated. (236 aa)
FGF2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (155 aa)
FGF14Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (163 aa)
FGF5Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (244 aa)
CSF1RColony stimulating factor 1 receptor. (968 aa)
FGF7Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (194 aa)
FGF18Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (209 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
SP7Sp7 transcription factor. (431 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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