(14 nodes) (2023) Emerging mechanisms and functions of inflammasome complexes in teleost fish. network (Latimeria chalumnae)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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experimentally determined

Predicted Interactions

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Your Input:
	IL18	Uncharacterized protein. (200 aa)
	AIM2	HIN-200 domain-containing protein. (205 aa)
	MYD88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
	DPP8	Dipeptidyl peptidase 8; Belongs to the peptidase S9B family. (883 aa)
	LOC102367521	Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
	NLRC4	NLR family CARD domain containing 4. (1032 aa)
	SYK	Tyrosine-protein kinase. (616 aa)
	RIPK1	Receptor interacting serine/threonine kinase 1. (667 aa)
	LOC102351339	CARD- and ANK-containing Inflammasome Adaptor Protein. (757 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
	CASP6	Caspase 6; Belongs to the peptidase C14A family. (269 aa)
	M3XJL3_LATCH	HIN-200 domain-containing protein. (217 aa)
	CASP7	Caspase 7; Belongs to the peptidase C14A family. (313 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AIM2	IL18	ENSLACP00000021844	ENSLACP00000021930	HIN-200 domain-containing protein.	Uncharacterized protein.	0.717
AIM2	MYD88	ENSLACP00000021844	ENSLACP00000019094	HIN-200 domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.462
AIM2	NLRC4	ENSLACP00000021844	ENSLACP00000014259	HIN-200 domain-containing protein.	NLR family CARD domain containing 4.	0.910
CASP6	LOC102367521	ENSLACP00000002246	ENSLACP00000014331	Caspase 6; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.588
CASP6	RIPK1	ENSLACP00000002246	ENSLACP00000011259	Caspase 6; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 1.	0.585
CASP7	LOC102367521	ENSLACP00000022676	ENSLACP00000014331	Caspase 7; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.964
CASP7	RIPK1	ENSLACP00000022676	ENSLACP00000011259	Caspase 7; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 1.	0.531
IL18	AIM2	ENSLACP00000021930	ENSLACP00000021844	Uncharacterized protein.	HIN-200 domain-containing protein.	0.717
IL18	M3XJL3_LATCH	ENSLACP00000021930	ENSLACP00000022919	Uncharacterized protein.	HIN-200 domain-containing protein.	0.575
IL18	MYD88	ENSLACP00000021930	ENSLACP00000019094	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.792
IL18	NLRC4	ENSLACP00000021930	ENSLACP00000014259	Uncharacterized protein.	NLR family CARD domain containing 4.	0.687
LOC102351339	NLRC4	ENSLACP00000004802	ENSLACP00000014259	CARD- and ANK-containing Inflammasome Adaptor Protein.	NLR family CARD domain containing 4.	0.651
LOC102367521	CASP6	ENSLACP00000014331	ENSLACP00000002246	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 6; Belongs to the peptidase C14A family.	0.588
LOC102367521	CASP7	ENSLACP00000014331	ENSLACP00000022676	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 7; Belongs to the peptidase C14A family.	0.964
LOC102367521	RIPK1	ENSLACP00000014331	ENSLACP00000011259	Uncharacterized protein; Belongs to the peptidase C14A family.	Receptor interacting serine/threonine kinase 1.	0.619
M3XJL3_LATCH	IL18	ENSLACP00000022919	ENSLACP00000021930	HIN-200 domain-containing protein.	Uncharacterized protein.	0.575
M3XJL3_LATCH	MYD88	ENSLACP00000022919	ENSLACP00000019094	HIN-200 domain-containing protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.452
M3XJL3_LATCH	NLRC4	ENSLACP00000022919	ENSLACP00000014259	HIN-200 domain-containing protein.	NLR family CARD domain containing 4.	0.546
MYD88	AIM2	ENSLACP00000019094	ENSLACP00000021844	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	HIN-200 domain-containing protein.	0.462
MYD88	IL18	ENSLACP00000019094	ENSLACP00000021930	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	Uncharacterized protein.	0.792