(10 nodes) (2023) Integration of microRNA and mRNA analyses depicts the potential roles of Momordica charantia saponin administration in insulin resistance of juvenile common carp (Cyprinus carpio) fed with a high-starch diet. network (Latimeria chalumnae)

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Your Input:
	LOC102348007	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (392 aa)
	LOC102358202	Tyrosine-protein kinase receptor. (838 aa)
	H3ACE0_LATCH	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
	SIRT1	Sirtuin 1. (729 aa)
	AMH	Anti-Mullerian hormone. (562 aa)
	INSR	Uncharacterized protein. (270 aa)
	FOXO1	Forkhead box O1. (633 aa)
	IRS1	Insulin receptor substrate 1. (1076 aa)
	H3B8U3_LATCH	Serine/threonine-protein kinase TOR. (1418 aa)
	MTOR	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
FOXO1	H3ACE0_LATCH	ENSLACP00000011598	ENSLACP00000007311	Forkhead box O1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.600
FOXO1	IRS1	ENSLACP00000011598	ENSLACP00000016025	Forkhead box O1.	Insulin receptor substrate 1.	0.500
FOXO1	SIRT1	ENSLACP00000011598	ENSLACP00000009079	Forkhead box O1.	Sirtuin 1.	0.908
H3ACE0_LATCH	FOXO1	ENSLACP00000007311	ENSLACP00000011598	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Forkhead box O1.	0.600
H3ACE0_LATCH	INSR	ENSLACP00000007311	ENSLACP00000011313	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Uncharacterized protein.	0.805
H3ACE0_LATCH	IRS1	ENSLACP00000007311	ENSLACP00000016025	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Insulin receptor substrate 1.	0.824
H3ACE0_LATCH	LOC102348007	ENSLACP00000007311	ENSLACP00000008684	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.450
H3ACE0_LATCH	LOC102358202	ENSLACP00000007311	ENSLACP00000005349	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Tyrosine-protein kinase receptor.	0.805
H3ACE0_LATCH	SIRT1	ENSLACP00000007311	ENSLACP00000009079	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	Sirtuin 1.	0.688
H3B8U3_LATCH	MTOR	ENSLACP00000018314	ENSLACP00000018843	Serine/threonine-protein kinase TOR.	Mechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family.	0.944
H3B8U3_LATCH	SIRT1	ENSLACP00000018314	ENSLACP00000009079	Serine/threonine-protein kinase TOR.	Sirtuin 1.	0.572
INSR	H3ACE0_LATCH	ENSLACP00000011313	ENSLACP00000007311	Uncharacterized protein.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.805
INSR	IRS1	ENSLACP00000011313	ENSLACP00000016025	Uncharacterized protein.	Insulin receptor substrate 1.	0.652
INSR	LOC102348007	ENSLACP00000011313	ENSLACP00000008684	Uncharacterized protein.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.582
INSR	LOC102358202	ENSLACP00000011313	ENSLACP00000005349	Uncharacterized protein.	Tyrosine-protein kinase receptor.	0.900
IRS1	FOXO1	ENSLACP00000016025	ENSLACP00000011598	Insulin receptor substrate 1.	Forkhead box O1.	0.500
IRS1	H3ACE0_LATCH	ENSLACP00000016025	ENSLACP00000007311	Insulin receptor substrate 1.	Insulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.	0.824
IRS1	INSR	ENSLACP00000016025	ENSLACP00000011313	Insulin receptor substrate 1.	Uncharacterized protein.	0.652
IRS1	LOC102348007	ENSLACP00000016025	ENSLACP00000008684	Insulin receptor substrate 1.	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma).	0.982
IRS1	LOC102358202	ENSLACP00000016025	ENSLACP00000005349	Insulin receptor substrate 1.	Tyrosine-protein kinase receptor.	0.652