STRINGSTRING
PAX7 PAX7 MYLK MYLK TGFBR2 TGFBR2 SMAD6 SMAD6 SMAD7 SMAD7 H3ACE0_LATCH H3ACE0_LATCH MYH11 MYH11 SMAD3 SMAD3 LOC102357987 LOC102357987 MYOG MYOG LFNG LFNG HEY1 HEY1 HOXC9 HOXC9 LOC102352268 LOC102352268 HES4 HES4 NOTCH1 NOTCH1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
PAX7Paired box 7. (420 aa)
MYLKMyosin light chain kinase. (1156 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (585 aa)
SMAD6Mothers against decapentaplegic homolog. (485 aa)
SMAD7Mothers against decapentaplegic homolog. (377 aa)
H3ACE0_LATCHInsulin; Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver. (111 aa)
MYH11Myosin heavy chain 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (1949 aa)
SMAD3Mothers against decapentaplegic homolog. (358 aa)
LOC102357987Uncharacterized protein. (2519 aa)
MYOGMyogenin. (242 aa)
LFNGBeta-1,3-N-acetylglucosaminyltransferase. (381 aa)
HEY1Hes related family bHLH transcription factor with YRPW motif 1. (304 aa)
HOXC9Homeobox protein; Sequence-specific transcription factor which is part of a developmental regulatory system that provides cells with specific positional identities on the anterior-posterior axis. Belongs to the Abd-B homeobox family. (264 aa)
LOC102352268Transforming growth factor beta; Belongs to the TGF-beta family. (414 aa)
HES4Hes family bHLH transcription factor 4. (296 aa)
NOTCH1Notch receptor 1. (2494 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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