STRINGSTRING
SAG SAG RPAP1 RPAP1 LEPR LEPR HDAC11 HDAC11 FGFRL1 FGFRL1 LEP LEP ETNPPL ETNPPL FGF12 FGF12 HDAC7 HDAC7
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
SAGS-antigen visual arrestin. (317 aa)
RPAP1RNA polymerase II associated protein 1. (1397 aa)
LEPRLeptin receptor. (1149 aa)
HDAC11Histone deacetylase 11. (389 aa)
FGFRL1Fibroblast growth factor receptor like 1. (480 aa)
LEPLeptin; Key player in the regulation of energy balance and body weight control. Once released into the circulation, has central and peripheral effects by binding LEPR, found in many tissues, which results in the activation of several major signaling pathways. Belongs to the leptin family. (169 aa)
ETNPPLEthanolamine-phosphate phospho-lyase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. (524 aa)
FGF12Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (243 aa)
HDAC7Histone deacetylase; Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regulation, cell cycle progression and developmental events. (873 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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