(74 nodes) EGF domain, unclasssified subfamily network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TENM3	Uncharacterized protein. (2590 aa)
	H3B9C8_LATCH	Uncharacterized protein. (1065 aa)
	H3BAG9_LATCH	Uncharacterized protein. (255 aa)
	H3BAT8_LATCH	Uncharacterized protein. (156 aa)
	NELL2	Neural EGFL like 2. (715 aa)
	LOC102361865	Zgc:158328. (1352 aa)
	H3BEP8_LATCH	Uncharacterized protein. (556 aa)
	H3BES4_LATCH	Uncharacterized protein. (558 aa)
	LOC102364760	Uncharacterized protein. (986 aa)
	PCSK6	Proprotein convertase subtilisin/kexin type 6; Belongs to the peptidase S8 family. (799 aa)
	LRP1	LDL receptor related protein 1. (4329 aa)
	STAB1	Stabilin 1. (2568 aa)
	H3BHF5_LATCH	Uncharacterized protein. (848 aa)
	LRP4	LDL receptor related protein 4. (1896 aa)
	FBLN5	Fibulin 5. (436 aa)
	MEGF6	Multiple EGF like domains 6. (1397 aa)
	LRP2	LDL receptor related protein 2. (4649 aa)
	CNTNAP1	Contactin associated protein 1. (1291 aa)
	RELN	Reelin. (3462 aa)
	LAMC2	Uncharacterized protein. (1189 aa)
	VLDLR	Very low density lipoprotein receptor. (885 aa)
	LOC102345355	Uncharacterized protein. (276 aa)
	LOC102351448	Uncharacterized protein. (5563 aa)
	LAMA5	Laminin subunit alpha 5. (3482 aa)
	EFEMP1	EGF containing fibulin extracellular matrix protein 1. (323 aa)
	LAMA2	Uncharacterized protein. (3000 aa)
	H3AR79_LATCH	Uncharacterized protein. (411 aa)
	STAB2	Stabilin 2. (2236 aa)
	LTBP1	Latent transforming growth factor beta binding protein 1. (1433 aa)
	SORL1	Sortilin-related receptor, L(DLR class) A repeats containing. (1410 aa)
	MEGF11	Multiple EGF like domains 11. (963 aa)
	FBLN2	Fibulin 2. (1176 aa)
	WIF1	WNT inhibitory factor 1. (379 aa)
	ZAN	Zonadhesin (gene/pseudogene). (2214 aa)
	LOC102350991	Uncharacterized protein. (1471 aa)
	SCARF1	Scavenger receptor class F member 1. (759 aa)
	FRAS1	Uncharacterized protein. (630 aa)
	PAMR1	Peptidase domain containing associated with muscle regeneration 1; Belongs to the peptidase S1 family. (700 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa)
	EFEMP2	EGF containing fibulin extracellular matrix protein 2. (446 aa)
	FCGBP	Uncharacterized protein. (2249 aa)
	TNXB	Uncharacterized protein. (1830 aa)
	LDLRAD3	Low density lipoprotein receptor class A domain containing 3. (328 aa)
	LAMB2	Laminin subunit beta 2. (1781 aa)
	TENM2	Uncharacterized protein. (596 aa)
	ATRN	Attractin. (1185 aa)
	H3B5B5_LATCH	Uncharacterized protein. (264 aa)
	LAMA4	Laminin subunit alpha 4. (1721 aa)
	THBS4	Thrombospondin 4. (919 aa)
	OTOGL	Otogelin like. (2821 aa)
	H2ZRI0_LATCH	Uncharacterized protein. (277 aa)
	LAMA1	Laminin subunit alpha 1. (2379 aa)
	TNR	Tenascin R. (992 aa)
	NTN4	Netrin 4. (345 aa)
	EGFLAM	EGF like, fibronectin type III and laminin G domains. (587 aa)
	ITGB1	Integrin beta; Belongs to the integrin beta chain family. (822 aa)
	H2ZVE3_LATCH	Uncharacterized protein. (238 aa)
	H2ZW79_LATCH	Uncharacterized protein. (2340 aa)
	NAGPA	N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase. (588 aa)
	LAMC1	Laminin subunit gamma 1. (1472 aa)
	THBS2	Uncharacterized protein. (1177 aa)
	H3A1D6_LATCH	Uncharacterized protein. (1979 aa)
	H3A1M2_LATCH	Uncharacterized protein. (1602 aa)
	TNC	Tenascin C. (2213 aa)
	LOC102359917	SEA domain-containing protein. (1102 aa)
	SCARF2	Scavenger receptor class F member 2. (821 aa)
	IMPG2	Interphotoreceptor matrix proteoglycan 2. (1453 aa)
	H3A5Z1_LATCH	Uncharacterized protein. (223 aa)
	MEGF8	Multiple EGF like domains 8. (2553 aa)
	H3A9E2_LATCH	Uncharacterized protein. (1114 aa)
	H3ABR4_LATCH	Uncharacterized protein. (272 aa)
	RSPO4	R-spondin 4. (184 aa)
	TIE1	Tyrosine kinase with immunoglobulin like and EGF like domains 1. (1143 aa)
	FBLN7	Fibulin 7. (443 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
EFEMP2	FRAS1	ENSLACP00000014780	ENSLACP00000013945	EGF containing fibulin extracellular matrix protein 2.	Uncharacterized protein.	0.498
EFEMP2	LAMC1	ENSLACP00000014780	ENSLACP00000002940	EGF containing fibulin extracellular matrix protein 2.	Laminin subunit gamma 1.	0.444
EGFLAM	FRAS1	ENSLACP00000000978	ENSLACP00000013945	EGF like, fibronectin type III and laminin G domains.	Uncharacterized protein.	0.416
EGFLAM	H3A5Z1_LATCH	ENSLACP00000000978	ENSLACP00000005062	EGF like, fibronectin type III and laminin G domains.	Uncharacterized protein.	0.421
EGFLAM	H3ABR4_LATCH	ENSLACP00000000978	ENSLACP00000007085	EGF like, fibronectin type III and laminin G domains.	Uncharacterized protein.	0.421
EGFLAM	LDLRAD3	ENSLACP00000000978	ENSLACP00000015680	EGF like, fibronectin type III and laminin G domains.	Low density lipoprotein receptor class A domain containing 3.	0.421
EGFLAM	LRP1	ENSLACP00000000978	ENSLACP00000021100	EGF like, fibronectin type III and laminin G domains.	LDL receptor related protein 1.	0.421
EGFLAM	LRP2	ENSLACP00000000978	ENSLACP00000021820	EGF like, fibronectin type III and laminin G domains.	LDL receptor related protein 2.	0.421
EGFLAM	LRP4	ENSLACP00000000978	ENSLACP00000021426	EGF like, fibronectin type III and laminin G domains.	LDL receptor related protein 4.	0.421
EGFLAM	SORL1	ENSLACP00000000978	ENSLACP00000012330	EGF like, fibronectin type III and laminin G domains.	Sortilin-related receptor, L(DLR class) A repeats containing.	0.479
EGFLAM	TNC	ENSLACP00000000978	ENSLACP00000003703	EGF like, fibronectin type III and laminin G domains.	Tenascin C.	0.403
EGFLAM	TNR	ENSLACP00000000978	ENSLACP00000000550	EGF like, fibronectin type III and laminin G domains.	Tenascin R.	0.403
EGFLAM	TNXB	ENSLACP00000000978	ENSLACP00000015120	EGF like, fibronectin type III and laminin G domains.	Uncharacterized protein.	0.403
EGFLAM	VLDLR	ENSLACP00000000978	ENSLACP00000023007	EGF like, fibronectin type III and laminin G domains.	Very low density lipoprotein receptor.	0.421
FRAS1	EFEMP2	ENSLACP00000013945	ENSLACP00000014780	Uncharacterized protein.	EGF containing fibulin extracellular matrix protein 2.	0.498
FRAS1	EGFLAM	ENSLACP00000013945	ENSLACP00000000978	Uncharacterized protein.	EGF like, fibronectin type III and laminin G domains.	0.416
H3A5Z1_LATCH	EGFLAM	ENSLACP00000005062	ENSLACP00000000978	Uncharacterized protein.	EGF like, fibronectin type III and laminin G domains.	0.421
H3A5Z1_LATCH	H3ABR4_LATCH	ENSLACP00000005062	ENSLACP00000007085	Uncharacterized protein.	Uncharacterized protein.	0.900
H3A5Z1_LATCH	RELN	ENSLACP00000005062	ENSLACP00000022206	Uncharacterized protein.	Reelin.	0.603
H3A5Z1_LATCH	SORL1	ENSLACP00000005062	ENSLACP00000012330	Uncharacterized protein.	Sortilin-related receptor, L(DLR class) A repeats containing.	0.500