(25 nodes) C-terminal cystine knot-like domain (CTCK) network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCN2	Cellular communication network factor 2. (344 aa)
	LOC102350871	Uncharacterized protein. (1005 aa)
	LOC102353315	Uncharacterized protein. (381 aa)
	MUC5AC	Uncharacterized protein. (2574 aa)
	LOC102350164	Uncharacterized protein. (364 aa)
	CER1	CTCK domain-containing protein. (257 aa)
	CCN5	Cellular communication network factor 5. (329 aa)
	GREM1	Gremlin 1, DAN family BMP antagonist. (189 aa)
	H3ACJ0_LATCH	Cellular communication network factor 2b. (348 aa)
	CCN3	Cellular communication network factor 3. (345 aa)
	CCN4	Cellular communication network factor 4. (357 aa)
	NBL1	NBL1, DAN family BMP antagonist. (184 aa)
	SOST	Sclerostin. (210 aa)
	SLIT2	Slit guidance ligand 2. (1372 aa)
	NDP	CTCK domain-containing protein. (132 aa)
	LOC102363594	Uncharacterized protein. (372 aa)
	VWF	Von Willebrand factor. (2833 aa)
	GREM2	Gremlin 2, DAN family BMP antagonist. (167 aa)
	CCN6	Cellular communication network factor 6. (354 aa)
	OTOG	Otogelin. (2804 aa)
	DAND5	CTCK domain-containing protein. (247 aa)
	OTOGL	Otogelin like. (2821 aa)
	CCN1	Cellular communication network factor 1. (368 aa)
	LOC102356073	CTCK domain-containing protein. (167 aa)
	SLIT3	Slit guidance ligand 3. (635 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CCN1	CCN2	ENSLACP00000019670	ENSLACP00000000493	Cellular communication network factor 1.	Cellular communication network factor 2.	0.565
CCN2	CCN1	ENSLACP00000000493	ENSLACP00000019670	Cellular communication network factor 2.	Cellular communication network factor 1.	0.565
CCN2	H3ACJ0_LATCH	ENSLACP00000000493	ENSLACP00000007361	Cellular communication network factor 2.	Cellular communication network factor 2b.	0.902
CCN2	LOC102350164	ENSLACP00000000493	ENSLACP00000003199	Cellular communication network factor 2.	Uncharacterized protein.	0.570
CCN2	LOC102353315	ENSLACP00000000493	ENSLACP00000001383	Cellular communication network factor 2.	Uncharacterized protein.	0.486
CER1	GREM2	ENSLACP00000003380	ENSLACP00000015241	CTCK domain-containing protein.	Gremlin 2, DAN family BMP antagonist.	0.426
CER1	SOST	ENSLACP00000003380	ENSLACP00000011848	CTCK domain-containing protein.	Sclerostin.	0.575
GREM1	GREM2	ENSLACP00000007025	ENSLACP00000015241	Gremlin 1, DAN family BMP antagonist.	Gremlin 2, DAN family BMP antagonist.	0.902
GREM1	LOC102356073	ENSLACP00000007025	ENSLACP00000021067	Gremlin 1, DAN family BMP antagonist.	CTCK domain-containing protein.	0.903
GREM2	CER1	ENSLACP00000015241	ENSLACP00000003380	Gremlin 2, DAN family BMP antagonist.	CTCK domain-containing protein.	0.426
GREM2	GREM1	ENSLACP00000015241	ENSLACP00000007025	Gremlin 2, DAN family BMP antagonist.	Gremlin 1, DAN family BMP antagonist.	0.902
GREM2	LOC102356073	ENSLACP00000015241	ENSLACP00000021067	Gremlin 2, DAN family BMP antagonist.	CTCK domain-containing protein.	0.903
GREM2	SOST	ENSLACP00000015241	ENSLACP00000011848	Gremlin 2, DAN family BMP antagonist.	Sclerostin.	0.617
H3ACJ0_LATCH	CCN2	ENSLACP00000007361	ENSLACP00000000493	Cellular communication network factor 2b.	Cellular communication network factor 2.	0.902
LOC102350164	CCN2	ENSLACP00000003199	ENSLACP00000000493	Uncharacterized protein.	Cellular communication network factor 2.	0.570
LOC102353315	CCN2	ENSLACP00000001383	ENSLACP00000000493	Uncharacterized protein.	Cellular communication network factor 2.	0.486
LOC102356073	GREM1	ENSLACP00000021067	ENSLACP00000007025	CTCK domain-containing protein.	Gremlin 1, DAN family BMP antagonist.	0.903
LOC102356073	GREM2	ENSLACP00000021067	ENSLACP00000015241	CTCK domain-containing protein.	Gremlin 2, DAN family BMP antagonist.	0.903
NDP	SOST	ENSLACP00000013174	ENSLACP00000011848	CTCK domain-containing protein.	Sclerostin.	0.554
SOST	CER1	ENSLACP00000011848	ENSLACP00000003380	Sclerostin.	CTCK domain-containing protein.	0.575