(15 nodes) Meprin and TRAF homology network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	TRAF1	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (565 aa)
	H3AZ94_LATCH	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (564 aa)
	MEP1A	Meprin A subunit. (655 aa)
	TRAF2	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (580 aa)
	H3APL3_LATCH	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (534 aa)
	TRAF4	TNF receptor-associated factor. (434 aa)
	TRAF3	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
	SPOP	Speckle type BTB/POZ protein. (374 aa)
	SPOPL	Speckle type BTB/POZ protein like. (392 aa)
	TRIM37	Tripartite motif containing 37. (939 aa)
	USP7	Ubiquitin specific peptidase 7; Belongs to the peptidase C19 family. (1101 aa)
	TRAF6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
	MEP1B	Meprin A subunit beta. (663 aa)
	H3B7S8_LATCH	TNF receptor-associated factor. (449 aa)
	TRAF5	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (556 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
H3APL3_LATCH	H3B7S8_LATCH	ENSLACP00000011584	ENSLACP00000017949	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor.	0.559
H3APL3_LATCH	TRAF1	ENSLACP00000011584	ENSLACP00000015272	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.546
H3APL3_LATCH	TRAF2	ENSLACP00000011584	ENSLACP00000011356	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.553
H3APL3_LATCH	TRAF6	ENSLACP00000011584	ENSLACP00000003556	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.822
H3APL3_LATCH	TRIM37	ENSLACP00000011584	ENSLACP00000005384	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Tripartite motif containing 37.	0.430
H3AZ94_LATCH	H3B7S8_LATCH	ENSLACP00000014965	ENSLACP00000017949	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor.	0.651
H3AZ94_LATCH	TRAF1	ENSLACP00000014965	ENSLACP00000015272	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.646
H3AZ94_LATCH	TRAF2	ENSLACP00000014965	ENSLACP00000011356	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.640
H3AZ94_LATCH	TRAF5	ENSLACP00000014965	ENSLACP00000017309	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.698
H3AZ94_LATCH	TRAF6	ENSLACP00000014965	ENSLACP00000003556	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.878
H3AZ94_LATCH	TRIM37	ENSLACP00000014965	ENSLACP00000005384	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	Tripartite motif containing 37.	0.430
H3B7S8_LATCH	H3APL3_LATCH	ENSLACP00000017949	ENSLACP00000011584	TNF receptor-associated factor.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.559
H3B7S8_LATCH	H3AZ94_LATCH	ENSLACP00000017949	ENSLACP00000014965	TNF receptor-associated factor.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.651
H3B7S8_LATCH	TRAF3	ENSLACP00000017949	ENSLACP00000010314	TNF receptor-associated factor.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.632
H3B7S8_LATCH	TRAF5	ENSLACP00000017949	ENSLACP00000017309	TNF receptor-associated factor.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.650
H3B7S8_LATCH	TRAF6	ENSLACP00000017949	ENSLACP00000003556	TNF receptor-associated factor.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.816
H3B7S8_LATCH	TRIM37	ENSLACP00000017949	ENSLACP00000005384	TNF receptor-associated factor.	Tripartite motif containing 37.	0.459
SPOP	SPOPL	ENSLACP00000008280	ENSLACP00000006719	Speckle type BTB/POZ protein.	Speckle type BTB/POZ protein like.	0.900
SPOPL	SPOP	ENSLACP00000006719	ENSLACP00000008280	Speckle type BTB/POZ protein like.	Speckle type BTB/POZ protein.	0.900
TRAF1	H3APL3_LATCH	ENSLACP00000015272	ENSLACP00000011584	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.546