(51 nodes) Von Willebrand factor (vWF) type C domain network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	OTOG	Otogelin. (2804 aa)
	LOC102353339	Uncharacterized protein. (1282 aa)
	CCN2	Cellular communication network factor 2. (344 aa)
	CHRD	Chordin; Belongs to the chordin family. (948 aa)
	LOC102350871	Uncharacterized protein. (1005 aa)
	JAG1	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1220 aa)
	LOC102353315	Uncharacterized protein. (381 aa)
	TECTA	Tectorin alpha. (2122 aa)
	H2ZVX8_LATCH	Uncharacterized protein. (1434 aa)
	H2ZW79_LATCH	Uncharacterized protein. (2340 aa)
	THBS2	Uncharacterized protein. (1177 aa)
	MUC5AC	Uncharacterized protein. (2574 aa)
	LOC102350164	Uncharacterized protein. (364 aa)
	CCN5	Cellular communication network factor 5. (329 aa)
	H3A4Z6_LATCH	Uncharacterized protein. (2029 aa)
	H3A523_LATCH	Si:dkey-266m15.6. (2232 aa)
	COL3A1	Uncharacterized protein. (1467 aa)
	DGCR2	DiGeorge syndrome critical region gene 2. (554 aa)
	H3ACJ0_LATCH	Cellular communication network factor 2b. (348 aa)
	CCN3	Cellular communication network factor 3. (345 aa)
	LOC102349917	Zgc:113531. (216 aa)
	H3AIN8_LATCH	Uncharacterized protein. (1963 aa)
	CCN4	Cellular communication network factor 4. (357 aa)
	CHRDL1	Chordin like 1. (458 aa)
	COL1A1	Collagen type I alpha 1 chain. (1486 aa)
	LOC102363594	Uncharacterized protein. (372 aa)
	VWF	Von Willebrand factor. (2833 aa)
	H3AUC5_LATCH	Uncharacterized protein. (1812 aa)
	LOC102346553	Si:dkey-6n6.1. (589 aa)
	FRAS1	Uncharacterized protein. (630 aa)
	PXDN	Peroxidasin. (1149 aa)
	H3AXK5_LATCH	Si:dkey-283b1.7. (242 aa)
	JAG2	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling. (1106 aa)
	FCGBP-2	Uncharacterized protein. (1566 aa)
	H3AZK1_LATCH	Uncharacterized protein. (1647 aa)
	FCGBP	Uncharacterized protein. (2249 aa)
	MUC19	Uncharacterized protein. (1147 aa)
	LOC102352767	VWFC domain-containing protein. (433 aa)
	VWC2	Von Willebrand factor C domain containing 2. (270 aa)
	H3B5B5_LATCH	Uncharacterized protein. (264 aa)
	VWC2L	Von Willebrand factor C domain containing 2 like. (176 aa)
	OTOGL	Otogelin like. (2821 aa)
	NELL2	Neural EGFL like 2. (715 aa)
	CCN1	Cellular communication network factor 1. (368 aa)
	CRIM1	Cysteine rich transmembrane BMP regulator 1. (881 aa)
	VWCE	Von Willebrand factor C and EGF domains. (620 aa)
	THBS1	Thrombospondin 1. (1170 aa)
	ECM2	Extracellular matrix protein 2. (713 aa)
	COL2A1	Collagen type II alpha 1 chain. (1488 aa)
	PXDNL	Peroxidasin like. (1276 aa)
	BMPER	BMP binding endothelial regulator. (682 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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structured XML interaction data, according to the 'PSI-MI' data standard

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMPER	CHRD	ENSLACP00000022404	ENSLACP00000000821	BMP binding endothelial regulator.	Chordin; Belongs to the chordin family.	0.714
CCN1	CCN2	ENSLACP00000019670	ENSLACP00000000493	Cellular communication network factor 1.	Cellular communication network factor 2.	0.565
CCN2	CCN1	ENSLACP00000000493	ENSLACP00000019670	Cellular communication network factor 2.	Cellular communication network factor 1.	0.565
CCN2	H3ACJ0_LATCH	ENSLACP00000000493	ENSLACP00000007361	Cellular communication network factor 2.	Cellular communication network factor 2b.	0.902
CCN2	LOC102350164	ENSLACP00000000493	ENSLACP00000003199	Cellular communication network factor 2.	Uncharacterized protein.	0.570
CCN2	LOC102353315	ENSLACP00000000493	ENSLACP00000001383	Cellular communication network factor 2.	Uncharacterized protein.	0.486
CCN2	THBS1	ENSLACP00000000493	ENSLACP00000020712	Cellular communication network factor 2.	Thrombospondin 1.	0.512
CHRD	BMPER	ENSLACP00000000821	ENSLACP00000022404	Chordin; Belongs to the chordin family.	BMP binding endothelial regulator.	0.714
H3ACJ0_LATCH	CCN2	ENSLACP00000007361	ENSLACP00000000493	Cellular communication network factor 2b.	Cellular communication network factor 2.	0.902
H3AZK1_LATCH	LOC102353339	ENSLACP00000015072	ENSLACP00000000386	Uncharacterized protein.	Uncharacterized protein.	0.687
H3AZK1_LATCH	MUC19	ENSLACP00000015072	ENSLACP00000015570	Uncharacterized protein.	Uncharacterized protein.	0.694
H3B5B5_LATCH	LOC102352767	ENSLACP00000017086	ENSLACP00000015612	Uncharacterized protein.	VWFC domain-containing protein.	0.900
JAG1	JAG2	ENSLACP00000001302	ENSLACP00000014617	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.958
JAG2	JAG1	ENSLACP00000014617	ENSLACP00000001302	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	Delta-like protein; Putative Notch ligand involved in the mediation of Notch signaling.	0.958
LOC102350164	CCN2	ENSLACP00000003199	ENSLACP00000000493	Uncharacterized protein.	Cellular communication network factor 2.	0.570
LOC102350871	THBS1	ENSLACP00000000837	ENSLACP00000020712	Uncharacterized protein.	Thrombospondin 1.	0.432
LOC102352767	H3B5B5_LATCH	ENSLACP00000015612	ENSLACP00000017086	VWFC domain-containing protein.	Uncharacterized protein.	0.900
LOC102353315	CCN2	ENSLACP00000001383	ENSLACP00000000493	Uncharacterized protein.	Cellular communication network factor 2.	0.486
LOC102353339	H3AZK1_LATCH	ENSLACP00000000386	ENSLACP00000015072	Uncharacterized protein.	Uncharacterized protein.	0.687
MUC19	H3AZK1_LATCH	ENSLACP00000015570	ENSLACP00000015072	Uncharacterized protein.	Uncharacterized protein.	0.694