(12 nodes) The RING-variant domain is a C4HC3 zinc-finger like motif found in a number of cellular and viral proteins. Some of these proteins have been shown both in vivo and in vitro to have ubiquitin E3 ligase activity. network (Latimeria chalumnae)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	MARCHF8	Membrane associated ring-CH-type finger 8. (476 aa)
	MARCHF3	Membrane associated ring-CH-type finger 3. (252 aa)
	MARCHF1	Membrane associated ring-CH-type finger 1. (496 aa)
	MARCHF7	Membrane associated ring-CH-type finger 7. (733 aa)
	MARCHF4	Membrane associated ring-CH-type finger 4. (266 aa)
	MARCHF11	Membrane associated ring-CH-type finger 11. (224 aa)
	MARCHF5	Membrane associated ring-CH-type finger 5. (280 aa)
	LOC102362671	Membrane-associated ring finger (C3HC4) 5, like. (286 aa)
	H3BCE5_LATCH	RING-CH-type domain-containing protein. (214 aa)
	MARCHF9	Membrane associated ring-CH-type finger 9. (339 aa)
	MARCHF2	Membrane associated ring-CH-type finger 2. (245 aa)
	MARCHF10	Membrane associated ring-CH-type finger 10. (782 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
MARCHF10	MARCHF11	ENSLACP00000023514	ENSLACP00000011904	Membrane associated ring-CH-type finger 10.	Membrane associated ring-CH-type finger 11.	0.680
MARCHF11	MARCHF10	ENSLACP00000011904	ENSLACP00000023514	Membrane associated ring-CH-type finger 11.	Membrane associated ring-CH-type finger 10.	0.680
MARCHF11	MARCHF7	ENSLACP00000011904	ENSLACP00000008027	Membrane associated ring-CH-type finger 11.	Membrane associated ring-CH-type finger 7.	0.551
MARCHF5	MARCHF8	ENSLACP00000014008	ENSLACP00000005351	Membrane associated ring-CH-type finger 5.	Membrane associated ring-CH-type finger 8.	0.445
MARCHF7	MARCHF11	ENSLACP00000008027	ENSLACP00000011904	Membrane associated ring-CH-type finger 7.	Membrane associated ring-CH-type finger 11.	0.551
MARCHF8	MARCHF5	ENSLACP00000005351	ENSLACP00000014008	Membrane associated ring-CH-type finger 8.	Membrane associated ring-CH-type finger 5.	0.445