STRINGSTRING
LOC102361787 LOC102361787 RGN RGN ADPGK ADPGK GPI GPI GOT2 GOT2 LOC102360660 LOC102360660 LOC102346076 LOC102346076 H2ZXP4_LATCH H2ZXP4_LATCH ENO2 ENO2 LOC102353852 LOC102353852 SDSL SDSL ACAT1 ACAT1 RPIA RPIA SUCLG1 SUCLG1 IDNK IDNK PRPS1 PRPS1 LOC102345272 LOC102345272 ECHS1 ECHS1 ESD ESD HAO1 HAO1 IDH3A IDH3A GCSH GCSH HK3 HK3 AGXT AGXT GLUD1 GLUD1 SDHA SDHA IDH3G IDH3G CAT CAT CPS1 CPS1 LOC102362883 LOC102362883 PGLS PGLS HKDC1 HKDC1 ALDOC ALDOC GLDC GLDC MTHFR MTHFR ME3 ME3 MMUT MMUT SUCLA2 SUCLA2 ALDOA ALDOA HK1 HK1 HAO2 HAO2 FBP1 FBP1 OGDHL OGDHL FBP2 FBP2 PDHA1 PDHA1 GAPDH GAPDH PCCB PCCB ACSS1 ACSS1 PDHB PDHB EHHADH EHHADH PCCA PCCA GCK GCK SDHC SDHC PGK1 PGK1 TKTL2 TKTL2 PGD PGD SUCLG2 SUCLG2 IDH1 IDH1 H6PD H6PD ENO3 ENO3 PGAM2 PGAM2 HIBCH HIBCH AMT AMT DLAT DLAT ENO1 ENO1 SDHD SDHD SDHB SDHB PGP PGP TALDO1 TALDO1 MDH1 MDH1 HK2 HK2 LOC102349397 LOC102349397 LOC102354033 LOC102354033 ACOX1 ACOX1 TKFC TKFC IDH2 IDH2 ACADS ACADS GLYCTK GLYCTK ALDH6A1 ALDH6A1 ACSS2 ACSS2 MCEE MCEE LOC102357659 LOC102357659 MDH2 MDH2 PC PC DLST DLST CS CS SHMT2 SHMT2 TKT TKT PSPH PSPH IDH3B IDH3B ALDOB ALDOB ACOX3 ACOX3 G6PD G6PD PKLR PKLR GOT1L1 GOT1L1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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LOC102361787Aminotran_1_2 domain-containing protein. (285 aa)
RGNRegucalcin. (299 aa)
ADPGKADP dependent glucokinase. (479 aa)
GPIGlucose-6-phosphate isomerase; Belongs to the GPI family. (555 aa)
GOT2Aspartate aminotransferase. (392 aa)
LOC102360660Aminotran_5 domain-containing protein. (368 aa)
LOC102346076Aminotran_5 domain-containing protein. (349 aa)
H2ZXP4_LATCHUncharacterized protein. (727 aa)
ENO2Enolase 2. (376 aa)
LOC102353852Uncharacterized protein. (971 aa)
SDSLSerine dehydratase like. (325 aa)
ACAT1Acetyl-CoA acetyltransferase 1; Belongs to the thiolase-like superfamily. Thiolase family. (422 aa)
RPIAUncharacterized protein. (92 aa)
SUCLG1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (335 aa)
IDNKGluconokinase; Belongs to the gluconokinase GntK/GntV family. (181 aa)
PRPS1Pribosyltran_N domain-containing protein. (339 aa)
LOC102345272Phosphoserine aminotransferase. (368 aa)
ECHS1Enoyl-CoA hydratase, short chain 1; Belongs to the enoyl-CoA hydratase/isomerase family. (290 aa)
ESDS-formylglutathione hydrolase; Serine hydrolase involved in the detoxification of formaldehyde. (282 aa)
HAO1Hydroxyacid oxidase 1. (370 aa)
IDH3AIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (366 aa)
GCSHGlycine cleavage system H protein; The H protein shuttles the methylamine group of glycine from the P protein to the T protein; Belongs to the GcvH family. (177 aa)
HK3Hexokinase 3. (908 aa)
AGXTSerine--pyruvate aminotransferase. (426 aa)
GLUD1Glutamate dehydrogenase 1b; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. (541 aa)
SDHASuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (670 aa)
IDH3GIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (400 aa)
CATCatalase; Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. (521 aa)
CPS1Carbamoyl-phosphate synthase 1. (1332 aa)
LOC102362883Iso_dh domain-containing protein. (384 aa)
PGLS6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (254 aa)
HKDC1Hexokinase domain containing 1. (923 aa)
ALDOCFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (340 aa)
GLDCGlycine cleavage system P protein; The glycine cleavage system catalyzes the degradation of glycine. (914 aa)
MTHFRMethylenetetrahydrofolate reductase; Belongs to the methylenetetrahydrofolate reductase family. (650 aa)
ME3Malic enzyme. (617 aa)
MMUTMethylmalonyl-CoA mutase. (754 aa)
SUCLA2Succinate-CoA ligase ADP-forming beta subunit. (374 aa)
ALDOAFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
HK1Hexokinase 1. (919 aa)
HAO2Hydroxyacid oxidase 2. (356 aa)
FBP1Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (338 aa)
OGDHLOxoglutarate dehydrogenase like. (1017 aa)
FBP2Fructose-bisphosphatase 2; Belongs to the FBPase class 1 family. (302 aa)
PDHA1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (400 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
PCCBPropionyl-CoA carboxylase subunit beta. (555 aa)
ACSS1Acetyl-coenzyme A synthetase. (645 aa)
PDHBPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (393 aa)
EHHADHEnoyl-CoA hydratase and 3-hydroxyacyl CoA dehydrogenase. (537 aa)
PCCAPropionyl-CoA carboxylase subunit alpha. (711 aa)
GCKPhosphotransferase. (400 aa)
SDHCSuccinate dehydrogenase complex subunit C. (168 aa)
PGK1Phosphoglycerate kinase. (389 aa)
TKTL2Transketolase like 2. (485 aa)
PGD6-phosphogluconate dehydrogenase, decarboxylating; Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH. (483 aa)
SUCLG2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (384 aa)
IDH1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (414 aa)
H6PDHexose-6-phosphate dehydrogenase/glucose 1-dehydrogenase. (793 aa)
ENO3Enolase 3. (434 aa)
PGAM2Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
HIBCH3-hydroxyisobutyryl-CoA hydrolase, mitochondrial; Hydrolyzes 3-hydroxyisobutyryl-CoA (HIBYL-CoA), a saline catabolite; Belongs to the enoyl-CoA hydratase/isomerase family. (387 aa)
AMTAminomethyltransferase; The glycine cleavage system catalyzes the degradation of glycine; Belongs to the GcvT family. (422 aa)
DLATAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (629 aa)
ENO1Enolase 1. (438 aa)
SDHDSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (156 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (285 aa)
PGPUncharacterized protein; Belongs to the HAD-like hydrolase superfamily. (313 aa)
TALDO1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (337 aa)
MDH1Malate dehydrogenase. (335 aa)
HK2Hexokinase 2. (918 aa)
LOC102349397Uncharacterized protein. (574 aa)
LOC102354033ADP-dependent glucokinase 2. (441 aa)
ACOX1Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (661 aa)
TKFCTriokinase and FMN cyclase. (582 aa)
IDH2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (402 aa)
ACADSAcyl-CoA dehydrogenase short chain. (410 aa)
GLYCTKGlycerate kinase. (413 aa)
ALDH6A1Aldehyde dehydrogenase 6 family member A1. (475 aa)
ACSS2Acyl-CoA synthetase short chain family member 2. (687 aa)
MCEEMethylmalonyl-CoA epimerase. (173 aa)
LOC102357659Uncharacterized protein. (518 aa)
MDH2Malate dehydrogenase. (337 aa)
PCPyruvate carboxylase. (722 aa)
DLSTDihydrolipoamide S-succinyltransferase. (458 aa)
CSCitrate synthase; Belongs to the citrate synthase family. (468 aa)
SHMT2Serine hydroxymethyltransferase; Interconversion of serine and glycine. Belongs to the SHMT family. (542 aa)
TKTTransketolase. (626 aa)
PSPHPhosphoserine phosphatase. (248 aa)
IDH3BIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (363 aa)
ALDOBFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (364 aa)
ACOX3Acyl-coenzyme A oxidase; Belongs to the acyl-CoA oxidase family. (708 aa)
G6PDGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (430 aa)
PKLRPyruvate kinase; Belongs to the pyruvate kinase family. (530 aa)
GOT1L1Glutamic-oxaloacetic transaminase 1 like 1. (405 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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