80 items (Latimeria chalumnae) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CDC16	Cell division cycle 16. (545 aa)
	LOC102360076	Protein kinase domain-containing protein. (286 aa)
	SMC1A	Structural maintenance of chromosomes protein. (1234 aa)
	PPP3CA	Serine/threonine-protein phosphatase. (287 aa)
	LOC102354262	Mitogen-activated protein kinase. (330 aa)
	YWHAZ	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (244 aa)
	MAPK14	Mitogen-activated protein kinase. (399 aa)
	H2ZXS9_LATCH	Cyclin N-terminal domain-containing protein; Belongs to the cyclin family. (398 aa)
	CCNE1	Cyclin E1; Belongs to the cyclin family. (417 aa)
	CCNB2	Cyclin B2; Belongs to the cyclin family. (404 aa)
	CUL1	Cullin 1; Belongs to the cullin family. (776 aa)
	ADCY4	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1092 aa)
	PLK1	Serine/threonine-protein kinase PLK. (595 aa)
	PPP3CC	Serine/threonine-protein phosphatase. (517 aa)
	ANAPC11	APC11 anaphase promoting complex subunit 11 homolog (yeast). (84 aa)
	LOC102361286	Calmodulin 2; Belongs to the calmodulin family. (149 aa)
	RBX1	Ring-box 1. (108 aa)
	YWHAG	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein gamma; Belongs to the 14-3-3 family. (247 aa)
	ADCY5-2	AC_N domain-containing protein. (323 aa)
	MAP2K1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (396 aa)
	YWHAB	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta; Belongs to the 14-3-3 family. (244 aa)
	ADCY9	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1340 aa)
	LOC102362951	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (351 aa)
	CCNB1	Cyclin B1; Belongs to the cyclin family. (404 aa)
	IGF1R	Insulin like growth factor 1 receptor. (1170 aa)
	RPS6KA1	Non-specific serine/threonine protein kinase. (712 aa)
	MAD2L1	Mitotic arrest deficient 2 like 1. (202 aa)
	PPP2R5B	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (495 aa)
	PPP1CA	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (344 aa)
	LOC102350821	Serine/threonine-protein phosphatase. (309 aa)
	LOC102359594	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	RPS6KA6	Ribosomal protein S6 kinase. (726 aa)
	FBXO5	F-box protein 5. (313 aa)
	CPEB2	Uncharacterized protein. (313 aa)
	PTTG1	Uncharacterized protein. (171 aa)
	ADCY8	AC_N domain-containing protein. (266 aa)
	YWHAQ	14_3_3 domain-containing protein; Belongs to the 14-3-3 family. (154 aa)
	SMC3	Structural maintenance of chromosomes protein. (1222 aa)
	PPP1CB	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
	SLK	STE20 like kinase. (1174 aa)
	CPEB3	Cytoplasmic polyadenylation element binding protein 3. (684 aa)
	ANAPC1	Anaphase promoting complex subunit 1. (1891 aa)
	PPP2R1A	Protein phosphatase 2 scaffold subunit Aalpha. (591 aa)
	SPDYA	Speedy/RINGO cell cycle regulator family member A. (294 aa)
	PRKACB	Uncharacterized protein; Belongs to the protein kinase superfamily. (351 aa)
	ANAPC13	Anaphase promoting complex subunit 13. (75 aa)
	ANAPC10	Anaphase promoting complex subunit 10. (147 aa)
	LOC102345989	Uncharacterized protein. (92 aa)
	ANAPC2	Anaphase promoting complex subunit 2; Belongs to the cullin family. (816 aa)
	MAPK1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
	CDC27	Cell division cycle 27. (833 aa)
	PPP1CC	Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
	MAPK11	Mitogen-activated protein kinase. (361 aa)
	LOC102365238	Ribosomal protein S6 kinase. (740 aa)
	CALML4	Calmodulin like 4. (165 aa)
	CPEB4	Cytoplasmic polyadenylation element binding protein 4. (726 aa)
	ANAPC7	Anaphase promoting complex subunit 7. (565 aa)
	ITPR3	Inositol 1,4,5-trisphosphate receptor type 3. (2675 aa)
	MAPK12	Uncharacterized protein. (103 aa)
	PPP2CA	Serine/threonine-protein phosphatase. (309 aa)
	SKP1	S-phase kinase associated protein 1; Belongs to the SKP1 family. (172 aa)
	ADCY6	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (894 aa)
	CDC23	Cell division cycle 23. (581 aa)
	YWHAH	Tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein eta; Belongs to the 14-3-3 family. (247 aa)
	PPP2R5E	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (467 aa)
	ANAPC5	Anaphase promoting complex subunit 5. (755 aa)
	PPP2R1B	Protein phosphatase 2 scaffold subunit Abeta. (589 aa)
	CDK2	Cyclin dependent kinase 2; Belongs to the protein kinase superfamily. (298 aa)
	CALML6	Calmodulin like 6. (160 aa)
	BUB1	BUB1 mitotic checkpoint serine/threonine kinase. (1272 aa)
	SPDYC	Speedy/RINGO cell cycle regulator family member C. (312 aa)
	FBXO43	F-box protein 43. (674 aa)
	PGR	Progesterone receptor. (770 aa)
	CDK1	Cyclin dependent kinase 1; Belongs to the protein kinase superfamily. (302 aa)
	PKMYT1	Protein kinase, membrane associated tyrosine/threonine 1. (563 aa)
	MAD1L1	Mitotic arrest deficient 1 like 1. (684 aa)
	CDC26	Cell division cycle 26. (85 aa)
	PPP2R5D	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (619 aa)
	IGF1	Insulin like growth factor 1. (136 aa)
	PPP2R5C	Serine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (610 aa)

Your Current Organism:

Latimeria chalumnae

NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADCY4	ADCY5-2	ENSLACP00000004616	ENSLACP00000006513	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	AC_N domain-containing protein.	0.962
ADCY4	ADCY6	ENSLACP00000004616	ENSLACP00000019614	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.971
ADCY4	ADCY8	ENSLACP00000004616	ENSLACP00000011649	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	AC_N domain-containing protein.	0.949
ADCY4	ADCY9	ENSLACP00000004616	ENSLACP00000007634	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.960
ADCY4	LOC102362951	ENSLACP00000004616	ENSLACP00000007730	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.920
ADCY4	PRKACB	ENSLACP00000004616	ENSLACP00000014312	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.920
ADCY5-2	ADCY4	ENSLACP00000006513	ENSLACP00000004616	AC_N domain-containing protein.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.962
ADCY5-2	ADCY6	ENSLACP00000006513	ENSLACP00000019614	AC_N domain-containing protein.	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.900
ADCY5-2	ADCY8	ENSLACP00000006513	ENSLACP00000011649	AC_N domain-containing protein.	AC_N domain-containing protein.	0.946
ADCY5-2	ADCY9	ENSLACP00000006513	ENSLACP00000007634	AC_N domain-containing protein.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.987
ADCY5-2	LOC102362951	ENSLACP00000006513	ENSLACP00000007730	AC_N domain-containing protein.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.920
ADCY5-2	PRKACB	ENSLACP00000006513	ENSLACP00000014312	AC_N domain-containing protein.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.920
ADCY6	ADCY4	ENSLACP00000019614	ENSLACP00000004616	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.971
ADCY6	ADCY5-2	ENSLACP00000019614	ENSLACP00000006513	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	AC_N domain-containing protein.	0.900
ADCY6	ADCY8	ENSLACP00000019614	ENSLACP00000011649	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	AC_N domain-containing protein.	0.946
ADCY6	ADCY9	ENSLACP00000019614	ENSLACP00000007634	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	0.958
ADCY6	LOC102362951	ENSLACP00000019614	ENSLACP00000007730	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily.	0.936
ADCY6	PRKACB	ENSLACP00000019614	ENSLACP00000014312	Adenylate cyclase 6; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Uncharacterized protein; Belongs to the protein kinase superfamily.	0.936
ADCY8	ADCY4	ENSLACP00000011649	ENSLACP00000004616	AC_N domain-containing protein.	Adenylate cyclase type 4; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling.	0.949
ADCY8	ADCY5-2	ENSLACP00000011649	ENSLACP00000006513	AC_N domain-containing protein.	AC_N domain-containing protein.	0.946