STRINGSTRING
TAB1 TAB1 H2ZUT7_LATCH H2ZUT7_LATCH LOC102354262 LOC102354262 MAPK14 MAPK14 CASP10 CASP10 MAPK9 MAPK9 IFNAR1 IFNAR1 TRAF6 TRAF6 TLR7 TLR7 AKT1 AKT1 LOC102363090 LOC102363090 JUN JUN IRF5 IRF5 CHUK CHUK MAP2K1 MAP2K1 H3AD77_LATCH H3AD77_LATCH LOC102348007 LOC102348007 IL6 IL6 LOC102351267 LOC102351267 FADD FADD MAPK10 MAPK10 TRAF3 TRAF3 MAP2K2 MAP2K2 TLR6 TLR6 IKBKE IKBKE MAP3K8 MAP3K8 TLR3 TLR3 TLR2 TLR2 PIK3CB PIK3CB RAC1 RAC1 PIK3R1 PIK3R1 MAPK1 MAPK1 MAP2K6 MAP2K6 LOC102350366 LOC102350366 LOC102366872 LOC102366872 PIK3CA PIK3CA MAPK11 MAPK11 MAPK12 MAPK12 TLR8 TLR8 MYD88 MYD88 TAB2 TAB2 NFKBIA NFKBIA LOC102355189 LOC102355189 TIRAP TIRAP FOS FOS TLR9 TLR9 MAPK8 MAPK8 M3XGJ3_LATCH M3XGJ3_LATCH LOC102352351 LOC102352351 AKT3 AKT3 CTSK CTSK TOLLIP TOLLIP LOC102352006 LOC102352006
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (436 aa)
H2ZUT7_LATCHTIR domain-containing protein. (1060 aa)
LOC102354262Mitogen-activated protein kinase. (330 aa)
MAPK14Mitogen-activated protein kinase. (399 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
IFNAR1Uncharacterized protein. (548 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
TLR7Toll-like receptor 7. (1033 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)
LOC102363090Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (97 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
IRF5Interferon regulatory factor 5. (515 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (700 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (396 aa)
H3AD77_LATCHJunE proto-oncogene, AP-1 transcription factor subunit. (316 aa)
LOC102348007Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (392 aa)
IL6Uncharacterized protein. (149 aa)
LOC102351267Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
FADDFas associated via death domain. (193 aa)
MAPK10Mitogen-activated protein kinase 10. (342 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
MAP2K2Mitogen-activated protein kinase kinase 2a. (301 aa)
TLR6Toll like receptor 6; Belongs to the Toll-like receptor family. (793 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (710 aa)
MAP3K8Mitogen-activated protein kinase kinase kinase 8. (477 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (766 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (798 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1077 aa)
RAC1Rac family small GTPase 1. (192 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (332 aa)
LOC102350366TIR domain-containing protein. (789 aa)
LOC102366872TIR domain-containing protein; Belongs to the Toll-like receptor family. (862 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
MAPK12Uncharacterized protein. (103 aa)
TLR8Toll like receptor 8; Belongs to the Toll-like receptor family. (1016 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (691 aa)
NFKBIANuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (298 aa)
LOC102355189Toll-like receptor 18; Belongs to the Toll-like receptor family. (797 aa)
TIRAPTIR domain containing adaptor protein. (267 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (391 aa)
TLR9Toll-like receptor 9. (1039 aa)
MAPK8Mitogen-activated protein kinase. (437 aa)
M3XGJ3_LATCHTNFR-Cys domain-containing protein. (163 aa)
LOC102352351C-C motif chemokine. (88 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
CTSKCathepsin K; Belongs to the peptidase C1 family. (333 aa)
TOLLIPToll interacting protein. (274 aa)
LOC102352006Uncharacterized protein. (163 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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