STRINGSTRING
TAB1 TAB1 BIRC2 BIRC2 LOC102357218 LOC102357218 LOC102345199 LOC102345199 LOC102354262 LOC102354262 MAPK14 MAPK14 CASP10 CASP10 LOC102347712 LOC102347712 MAPK9 MAPK9 FLNA FLNA ACBD3 ACBD3 DYNC1I1 DYNC1I1 DYNLT3 DYNLT3 LOC102348725 LOC102348725 PTPRC PTPRC TXN2 TXN2 TRAF6 TRAF6 DYNLRB2 DYNLRB2 EXOC4 EXOC4 LOC102363099 LOC102363099 LOC102362556 LOC102362556 VPS18 VPS18 RIPK2 RIPK2 M6PR M6PR PIK3C2G PIK3C2G LOC102348524 LOC102348524 AKT1 AKT1 MYL5 MYL5 ARF6 ARF6 LOC102363090 LOC102363090 LOC102357229 LOC102357229 JUN JUN LEF1 LEF1 KPNA1 KPNA1 LOC102363280 LOC102363280 HSP90B1 HSP90B1 H3A8L7_LATCH H3A8L7_LATCH RALA RALA NCKAP1 NCKAP1 PLEKHM1 PLEKHM1 LOC102366232 LOC102366232 RPS3 RPS3 VPS39 VPS39 BAX BAX CHUK CHUK MAP2K1 MAP2K1 CASP3 CASP3 H3AD77_LATCH H3AD77_LATCH LOC102350273 LOC102350273 DYNC1LI2 DYNC1LI2 PIK3CG PIK3CG RAF1 RAF1 ARPC2 ARPC2 FLNC FLNC NCKAP1L NCKAP1L PAK1 PAK1 IL6 IL6 DYNC1I2 DYNC1I2 LOC102351267 LOC102351267 FADD FADD LOC102352152 LOC102352152 LOC102349920 LOC102349920 SNX18 SNX18 MAPK10 MAPK10 ZFYVE21 ZFYVE21 LOC102356355 LOC102356355 DYNLT1 DYNLT1 H3AMW9_LATCH H3AMW9_LATCH H3AN42_LATCH H3AN42_LATCH KPNA4 KPNA4 MAP2K2 MAP2K2 LOC102355845 LOC102355845 RAB5C RAB5C TRAF2 TRAF2 ANXA9 ANXA9 HSP90AB1 HSP90AB1 LOC102346545 LOC102346545 LOC102357799 LOC102357799 LOC102359041 LOC102359041 GAPDH GAPDH RHOH RHOH KLC4 KLC4 LOC102362971 LOC102362971 ARPC1B ARPC1B LOC102362077 LOC102362077 KPNA3 KPNA3 CYTH3 CYTH3 LOC102361670 LOC102361670 KLC2 KLC2 TLR2 TLR2 LOC102367521 LOC102367521 WASL WASL RHOG RHOG PIK3CB PIK3CB RAC1 RAC1 VPS41 VPS41 MYL7 MYL7 FLNB FLNB DYNC1H1 DYNC1H1 MAPK1 MAPK1 STX10 STX10 RAB7B RAB7B H3B2N1_LATCH H3B2N1_LATCH LOC102363742 LOC102363742 H3B3L3_LATCH H3B3L3_LATCH TCF7L2-2 TCF7L2-2 NOD1 NOD1 MAP2K6 MAP2K6 LOC102350366 LOC102350366 CTNNB1 CTNNB1 MYL2 MYL2 LOC102366872 LOC102366872 PKN1 PKN1 TRADD TRADD PIK3CA PIK3CA DYNC2LI1 DYNC2LI1 ROCK2 ROCK2 MAPK11 MAPK11 ARHGEF26 ARHGEF26 RAB7A RAB7A MYL9 MYL9 CDC42 CDC42 EXOC2 EXOC2 ARPC3 ARPC3 CSE1L CSE1L BAK1 BAK1 MAPK12 MAPK12 TAB3 TAB3 SKP1 SKP1 MYD88 MYD88 TAB2 TAB2 RHOA RHOA ACTB ACTB PIK3C2A PIK3C2A ANXA2 ANXA2 VPS11 VPS11 NFKBIA NFKBIA LOC102355189 LOC102355189 RHOJ RHOJ TIRAP TIRAP RAB9B RAB9B ARF1 ARF1 FOS FOS DYNLL1 DYNLL1 ARPC5L ARPC5L TLR9 TLR9 HRAS HRAS MAPK8 MAPK8 LOC102349333 LOC102349333 EXOC5 EXOC5 RAB5B RAB5B LOC102350579 LOC102350579 LOC102350829 LOC102350829 IL18 IL18 DYNC1LI1 DYNC1LI1 PFN4 PFN4 M3XHT8_LATCH M3XHT8_LATCH LOC102346266 LOC102346266 AKT3 AKT3 CASP7 CASP7 ELMO2 ELMO2 LOC102362356 LOC102362356 LOC102352006 LOC102352006 LOC102348796 LOC102348796
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (436 aa)
BIRC2Baculoviral IAP repeat containing 2. (616 aa)
LOC102357218Heat shock protein 90, alpha (cytosolic), class A member 1, tandem duplicate 1. (730 aa)
LOC102345199Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (115 aa)
LOC102354262Mitogen-activated protein kinase. (330 aa)
MAPK14Mitogen-activated protein kinase. (399 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
LOC102347712Thioredoxin; Belongs to the thioredoxin family. (105 aa)
MAPK9Mitogen-activated protein kinase. (424 aa)
FLNAFilamin A. (2637 aa)
ACBD3Acyl-CoA binding domain containing 3. (525 aa)
DYNC1I1Uncharacterized protein. (99 aa)
DYNLT3Dynein light chain Tctex-type 3. (117 aa)
LOC102348725Uncharacterized protein. (641 aa)
PTPRCProtein tyrosine phosphatase receptor type C. (830 aa)
TXN2Thioredoxin 2. (162 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
DYNLRB2Dynein light chain roadblock. (109 aa)
EXOC4Exocyst complex component 4. (480 aa)
LOC102363099S_100 domain-containing protein; Belongs to the S-100 family. (98 aa)
LOC102362556Profilin; Belongs to the profilin family. (133 aa)
VPS18VPS18 core subunit of CORVET and HOPS complexes. (874 aa)
RIPK2Receptor interacting serine/threonine kinase 2. (567 aa)
M6PRMannose-6-phosphate receptor, cation dependent. (276 aa)
PIK3C2GPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1263 aa)
LOC102348524Uncharacterized protein. (193 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)
MYL5Myosin light chain 5. (188 aa)
ARF6ADP ribosylation factor 6; Belongs to the small GTPase superfamily. Arf family. (175 aa)
LOC102363090Multifunctional fusion protein; Belongs to the intercrine alpha (chemokine CxC) family. (97 aa)
LOC102357229WASP like actin nucleation promoting factor a. (194 aa)
JUNJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (311 aa)
LEF1Lymphoid enhancer binding factor 1. (397 aa)
KPNA1Importin subunit alpha; Belongs to the importin alpha family. (538 aa)
LOC102363280Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
HSP90B1Heat shock protein 90 beta family member 1. (800 aa)
H3A8L7_LATCHUncharacterized protein. (117 aa)
RALARAS like proto-oncogene A. (206 aa)
NCKAP1NCK associated protein 1. (1135 aa)
PLEKHM1Pleckstrin homology and RUN domain containing M1. (1054 aa)
LOC102366232RAB5B, member RAS oncogene family. (213 aa)
RPS3KH type-2 domain-containing protein; Belongs to the universal ribosomal protein uS3 family. (254 aa)
VPS39VPS39 subunit of HOPS complex. (875 aa)
BAXUncharacterized protein. (223 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (700 aa)
MAP2K1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (396 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
H3AD77_LATCHJunE proto-oncogene, AP-1 transcription factor subunit. (316 aa)
LOC102350273Uncharacterized protein. (196 aa)
DYNC1LI2Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (505 aa)
PIK3CGPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1106 aa)
RAF1Raf-1 proto-oncogene, serine/threonine kinase. (648 aa)
ARPC2Arp2/3 complex 34 kDa subunit; Functions as actin-binding component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (308 aa)
FLNCFilamin C. (2664 aa)
NCKAP1LNCK associated protein 1 like. (1132 aa)
PAK1Non-specific serine/threonine protein kinase. (545 aa)
IL6Uncharacterized protein. (149 aa)
DYNC1I2Dynein cytoplasmic 1 intermediate chain 2. (636 aa)
LOC102351267Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (338 aa)
FADDFas associated via death domain. (193 aa)
LOC102352152Uncharacterized protein. (206 aa)
LOC102349920Uncharacterized protein. (199 aa)
SNX18Sorting nexin. (587 aa)
MAPK10Mitogen-activated protein kinase 10. (342 aa)
ZFYVE21Kinesin light chain 1a. (634 aa)
LOC102356355TNFR-Cys domain-containing protein. (163 aa)
DYNLT1Dynein light chain Tctex-type 1. (113 aa)
H3AMW9_LATCHUncharacterized protein. (2007 aa)
H3AN42_LATCHUncharacterized protein. (369 aa)
KPNA4Importin subunit alpha; Belongs to the importin alpha family. (512 aa)
MAP2K2Mitogen-activated protein kinase kinase 2a. (301 aa)
LOC102355845Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
RAB5CRAB5C, member RAS oncogene family. (216 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (580 aa)
ANXA9Annexin. (348 aa)
HSP90AB1Heat shock protein 90 alpha family class B member 1. (734 aa)
LOC102346545Myosin, light chain 12, genome duplicate 2. (172 aa)
LOC102357799Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (189 aa)
LOC102359041Zgc:153993. (208 aa)
GAPDHGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
RHOHRas homolog family member H. (189 aa)
KLC4Kinesin light chain 4. (590 aa)
LOC102362971Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1081 aa)
ARPC1BActin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (368 aa)
LOC102362077Ras homolog gene family, member Gc. (192 aa)
KPNA3Importin subunit alpha; Belongs to the importin alpha family. (521 aa)
CYTH3Cytohesin 3. (394 aa)
LOC102361670Actin-related protein 2/3 complex subunit; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (376 aa)
KLC2TPR_REGION domain-containing protein. (603 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (798 aa)
LOC102367521Uncharacterized protein; Belongs to the peptidase C14A family. (253 aa)
WASLWASP like actin nucleation promoting factor. (314 aa)
RHOGRas homolog family member G. (191 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1077 aa)
RAC1Rac family small GTPase 1. (192 aa)
VPS41Vacuolar protein sorting-associated protein 41 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport pathways; Belongs to the VPS41 family. (804 aa)
MYL7Myosin light chain 7. (182 aa)
FLNBFilamin B. (2605 aa)
DYNC1H1Dynein cytoplasmic 1 heavy chain 1. (4615 aa)
MAPK1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (365 aa)
STX10Syntaxin 10. (252 aa)
RAB7BRAB7B, member RAS oncogene family. (201 aa)
H3B2N1_LATCHNACHT domain-containing protein. (429 aa)
LOC102363742Uncharacterized protein; Belongs to the peptidase C14A family. (394 aa)
H3B3L3_LATCHNACHT domain-containing protein. (837 aa)
TCF7L2-2Transcription factor 7 like 2. (180 aa)
NOD1Nucleotide binding oligomerization domain containing 1. (830 aa)
MAP2K6Mitogen-activated protein kinase kinase 6; Belongs to the protein kinase superfamily. (332 aa)
LOC102350366TIR domain-containing protein. (789 aa)
CTNNB1Catenin beta 1. (781 aa)
MYL2Myosin light chain 2. (148 aa)
LOC102366872TIR domain-containing protein; Belongs to the Toll-like receptor family. (862 aa)
PKN1Uncharacterized protein. (546 aa)
TRADDDeath domain-containing protein. (313 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
DYNC2LI1Dynein cytoplasmic 2 light intermediate chain 1. (362 aa)
ROCK2Rho associated coiled-coil containing protein kinase 2; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1462 aa)
MAPK11Mitogen-activated protein kinase. (361 aa)
ARHGEF26Rho guanine nucleotide exchange factor 26. (899 aa)
RAB7ARAB7A, member RAS oncogene family. (207 aa)
MYL9Myosin light chain 9. (173 aa)
CDC42Cell division cycle 42. (156 aa)
EXOC2Exocyst complex component 2; Component of the exocyst complex involved in the docking of exocytic vesicles with fusion sites on the plasma membrane. Belongs to the SEC5 family. (794 aa)
ARPC3Actin-related protein 2/3 complex subunit 3; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. (181 aa)
CSE1LChromosome segregation 1 like. (971 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
MAPK12Uncharacterized protein. (103 aa)
TAB3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (672 aa)
SKP1S-phase kinase associated protein 1; Belongs to the SKP1 family. (172 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (691 aa)
RHOAUncharacterized protein. (193 aa)
ACTBUncharacterized protein. (376 aa)
PIK3C2APhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1720 aa)
ANXA2Annexin. (338 aa)
VPS11Vacuolar protein sorting-associated protein 11 homolog; Plays a role in vesicle-mediated protein trafficking to lysosomal compartments including the endocytic membrane transport and autophagic pathways. Believed to act as a core component of the putative HOPS and CORVET endosomal tethering complexes. Belongs to the VPS11 family. (997 aa)
NFKBIANuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (298 aa)
LOC102355189Toll-like receptor 18; Belongs to the Toll-like receptor family. (797 aa)
RHOJRas homolog family member J. (136 aa)
TIRAPTIR domain containing adaptor protein. (267 aa)
RAB9BRAB9B, member RAS oncogene family. (213 aa)
ARF1ADP ribosylation factor 1; Belongs to the small GTPase superfamily. Arf family. (181 aa)
FOSFos proto-oncogene, AP-1 transcription factor subunit. (391 aa)
DYNLL1Dynein light chain. (115 aa)
ARPC5LActin-related protein 2/3 complex subunit 5; Functions as component of the Arp2/3 complex which is involved in regulation of actin polymerization and together with an activating nucleation-promoting factor (NPF) mediates the formation of branched actin networks. Arp2/3 complex plays a critical role in the control of cell morphogenesis via the modulation of cell polarity development. (150 aa)
TLR9Toll-like receptor 9. (1039 aa)
HRASHRas proto-oncogene, GTPase. (193 aa)
MAPK8Mitogen-activated protein kinase. (437 aa)
LOC102349333Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (176 aa)
EXOC5Exocyst complex component 5. (708 aa)
RAB5BRAB5B, member RAS oncogene family. (229 aa)
LOC102350579Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (181 aa)
LOC102350829Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (192 aa)
IL18Uncharacterized protein. (200 aa)
DYNC1LI1Dynein light intermediate chain; Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. (502 aa)
PFN4Profilin; Belongs to the profilin family. (128 aa)
M3XHT8_LATCHUncharacterized protein. (197 aa)
LOC102346266Uncharacterized protein. (503 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
CASP7Caspase 7; Belongs to the peptidase C14A family. (313 aa)
ELMO2Engulfment and cell motility 2. (724 aa)
LOC102362356Uncharacterized protein. (113 aa)
LOC102352006Uncharacterized protein. (163 aa)
LOC102348796Uncharacterized protein. (497 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
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