STRINGSTRING
H2ZSB6_LATCH H2ZSB6_LATCH TSC2 TSC2 LOC102346529 LOC102346529 LOC102355566 LOC102355566 DDX58 DDX58 LOC102367485 LOC102367485 TAB1 TAB1 H2ZT37_LATCH H2ZT37_LATCH LOC102357161 LOC102357161 H2ZTM7_LATCH H2ZTM7_LATCH BIRC2 BIRC2 LOC102359587 LOC102359587 H2ZU11_LATCH H2ZU11_LATCH LOC102345927 LOC102345927 LOC102345199 LOC102345199 LOC102365995 LOC102365995 NXF1 NXF1 H2ZVF6_LATCH H2ZVF6_LATCH CGAS CGAS CASP10 CASP10 LOC102351546 LOC102351546 H2ZY67_LATCH H2ZY67_LATCH H2ZYC5_LATCH H2ZYC5_LATCH Lach-UD-01 Lach-UD-01 H2ZYM4_LATCH H2ZYM4_LATCH LOC102363095 LOC102363095 H2ZZM1_LATCH H2ZZM1_LATCH IFNAR1 IFNAR1 LOC102345993 LOC102345993 LOC106706091 LOC106706091 TRAF6 TRAF6 H3A228_LATCH H3A228_LATCH LOC102348044 LOC102348044 H3A2S0_LATCH H3A2S0_LATCH STING1 STING1 SRSF7 SRSF7 H3A4I8_LATCH H3A4I8_LATCH AKT1 AKT1 LOC102361141 LOC102361141 LOC102363280 LOC102363280 LOC102357282 LOC102357282 SRSF6 SRSF6 Lach-UX-02 Lach-UX-02 H3A977_LATCH H3A977_LATCH Lach-UB-03 Lach-UB-03 ALYREF ALYREF H3AA83_LATCH H3AA83_LATCH SRSF5 SRSF5 JAK2 JAK2 EIF2AK2 EIF2AK2 BAX BAX CHUK CHUK PTPN11 PTPN11 SRC SRC CASP3 CASP3 JAK1 JAK1 LTA LTA Lach-UB-05 Lach-UB-05 Lach-UB-05-2 Lach-UB-05-2 H3AG87_LATCH H3AG87_LATCH LOC102348007 LOC102348007 LOC102350274 LOC102350274 EIF4EBP1 EIF4EBP1 SRSF3 SRSF3 IL6 IL6 FADD FADD H3AKQ1_LATCH H3AKQ1_LATCH TRAF3 TRAF3 TAPBP TAPBP EIF2S1 EIF2S1 LOC102365873 LOC102365873 PPP1CA PPP1CA SRSF4 SRSF4 LOC102356355 LOC102356355 LOC102359594 LOC102359594 H3AMT8_LATCH H3AMT8_LATCH TRAF2 TRAF2 POU2F2 POU2F2 PPP1CB PPP1CB POU2F3 POU2F3 IKBKE IKBKE Lach-UA-02 Lach-UA-02 LOC102359041 LOC102359041 LOC102360670 LOC102360670 TLR3 TLR3 LOC102350210 LOC102350210 SYK SYK IFIH1 IFIH1 EIF2B5 EIF2B5 RHEB RHEB C5 C5 TLR2 TLR2 APAF1 APAF1 PIK3CB PIK3CB PDIA3 PDIA3 SRSF2 SRSF2 Lach-UA-01 Lach-UA-01 PIK3R1 PIK3R1 LOC102365315 LOC102365315 TAP2 TAP2 TP53 TP53 TAP1 TAP1 SRSF1 SRSF1 NECTIN1 NECTIN1 LOC102347621 LOC102347621 LOC102350366 LOC102350366 FASLG FASLG TRADD TRADD PPP1CC PPP1CC PIK3CA PIK3CA LOC106703253 LOC106703253 LOC102354242 LOC102354242 CD74 CD74 BAK1 BAK1 C3 C3 MTOR MTOR H3BAI7_LATCH H3BAI7_LATCH MYD88 MYD88 TNFSF14 TNFSF14 TAB2 TAB2 EIF2B1 EIF2B1 SOCS3 SOCS3 NFKBIA NFKBIA LOC102355189 LOC102355189 CARD9 CARD9 SRSF9 SRSF9 CALR3 CALR3 TLR9 TLR9 LOC102349599 LOC102349599 LOC102360064 LOC102360064 LOC102360854 LOC102360854 TNFRSF14 TNFRSF14 RHEBL1 RHEBL1 ZNF91 ZNF91 AKT3 AKT3 LOC102358583 LOC102358583 M3XJZ2_LATCH M3XJZ2_LATCH M3XKG1_LATCH M3XKG1_LATCH LOC106706379 LOC106706379 LOC102348192 LOC102348192
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
H2ZSB6_LATCHIg-like domain-containing protein. (223 aa)
TSC2TSC complex subunit 2. (1836 aa)
LOC102346529Ig-like domain-containing protein. (152 aa)
LOC102355566Uncharacterized protein. (523 aa)
DDX58DExD/H-box helicase 58. (944 aa)
LOC102367485Ig-like domain-containing protein. (262 aa)
TAB1TGF-beta activated kinase 1 (MAP3K7) binding protein 1. (436 aa)
H2ZT37_LATCHIg-like domain-containing protein. (145 aa)
LOC102357161Ig-like domain-containing protein. (186 aa)
H2ZTM7_LATCHIg-like domain-containing protein. (206 aa)
BIRC2Baculoviral IAP repeat containing 2. (616 aa)
LOC102359587Uncharacterized protein. (646 aa)
H2ZU11_LATCHMHC_II_beta domain-containing protein. (97 aa)
LOC102345927Ig-like domain-containing protein. (221 aa)
LOC102345199Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (115 aa)
LOC102365995Uncharacterized protein. (407 aa)
NXF1Zgc:153681. (628 aa)
H2ZVF6_LATCHIg-like domain-containing protein; Belongs to the MHC class I family. (226 aa)
CGASCyclic GMP-AMP synthase. (370 aa)
CASP10Caspase 10; Belongs to the peptidase C14A family. (539 aa)
LOC102351546Ig-like domain-containing protein. (237 aa)
H2ZY67_LATCHUncharacterized protein. (779 aa)
H2ZYC5_LATCHIg-like domain-containing protein. (229 aa)
Lach-UD-01Ig-like domain-containing protein; Belongs to the MHC class I family. (342 aa)
H2ZYM4_LATCHUncharacterized protein. (990 aa)
LOC102363095Uncharacterized protein. (822 aa)
H2ZZM1_LATCHUncharacterized protein. (323 aa)
IFNAR1Uncharacterized protein. (548 aa)
LOC102345993Ig-like domain-containing protein. (254 aa)
LOC106706091Uncharacterized protein. (503 aa)
TRAF6TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (559 aa)
H3A228_LATCHUncharacterized protein. (577 aa)
LOC102348044Ig-like domain-containing protein; Belongs to the MHC class I family. (335 aa)
H3A2S0_LATCHIg-like domain-containing protein; Belongs to the MHC class I family. (354 aa)
STING1Uncharacterized protein. (380 aa)
SRSF7Serine and arginine rich splicing factor 7. (242 aa)
H3A4I8_LATCHIg-like domain-containing protein. (266 aa)
AKT1Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (478 aa)
LOC102361141TNF_2 domain-containing protein. (216 aa)
LOC102363280Cytochrome c domain-containing protein; Electron carrier protein. The oxidized form of the cytochrome c heme group can accept an electron from the heme group of the cytochrome c1 subunit of cytochrome reductase. Cytochrome c then transfers this electron to the cytochrome oxidase complex, the final protein carrier in the mitochondrial electron-transport chain. (104 aa)
LOC102357282Uncharacterized protein. (346 aa)
SRSF6Serine and arginine rich splicing factor 6. (338 aa)
Lach-UX-02IGc1 domain-containing protein. (48 aa)
H3A977_LATCHUncharacterized protein. (472 aa)
Lach-UB-03Ig-like domain-containing protein; Belongs to the MHC class I family. (358 aa)
ALYREFAly/REF export factor. (258 aa)
H3AA83_LATCHIg-like domain-containing protein. (267 aa)
SRSF5Serine and arginine rich splicing factor 5. (367 aa)
JAK2Tyrosine-protein kinase. (1152 aa)
EIF2AK2Protein kinase domain-containing protein. (292 aa)
BAXUncharacterized protein. (223 aa)
CHUKComponent of inhibitor of nuclear factor kappa B kinase complex. (700 aa)
PTPN11Protein tyrosine phosphatase non-receptor type 11. (586 aa)
SRCTyrosine-protein kinase. (535 aa)
CASP3Caspase 3; Belongs to the peptidase C14A family. (290 aa)
JAK1Janus kinase 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (613 aa)
LTALymphotoxin alpha. (166 aa)
Lach-UB-05Ig-like domain-containing protein. (157 aa)
Lach-UB-05-2Ig-like domain-containing protein. (338 aa)
H3AG87_LATCHIg-like domain-containing protein. (267 aa)
LOC102348007Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (392 aa)
LOC102350274Uncharacterized protein. (510 aa)
EIF4EBP1Eukaryotic translation initiation factor 4E binding protein 1. (113 aa)
SRSF3Serine and arginine rich splicing factor 3. (171 aa)
IL6Uncharacterized protein. (149 aa)
FADDFas associated via death domain. (193 aa)
H3AKQ1_LATCHUncharacterized protein. (338 aa)
TRAF3TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (567 aa)
TAPBPUncharacterized protein. (453 aa)
EIF2S1Eukaryotic translation initiation factor 2 subunit alpha. (315 aa)
LOC102365873Ig-like domain-containing protein; Belongs to the MHC class I family. (353 aa)
PPP1CASerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (344 aa)
SRSF4Serine and arginine rich splicing factor 6b. (491 aa)
LOC102356355TNFR-Cys domain-containing protein. (163 aa)
LOC102359594Serine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
H3AMT8_LATCHUncharacterized protein. (688 aa)
TRAF2TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (580 aa)
POU2F2POU domain protein. (546 aa)
PPP1CBSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (327 aa)
POU2F3POU domain protein. (387 aa)
IKBKEInhibitor of nuclear factor kappa B kinase subunit epsilon. (710 aa)
Lach-UA-02Ig-like domain-containing protein; Belongs to the MHC class I family. (428 aa)
LOC102359041Zgc:153993. (208 aa)
LOC102360670Uncharacterized protein. (209 aa)
TLR3Toll like receptor 3; Belongs to the Toll-like receptor family. (766 aa)
LOC102350210Zinc finger protein. (531 aa)
SYKTyrosine-protein kinase. (616 aa)
IFIH1Interferon induced with helicase C domain 1. (731 aa)
EIF2B5Eukaryotic translation initiation factor 2B subunit epsilon. (718 aa)
RHEBRas homolog, mTORC1 binding. (184 aa)
C5Complement C5. (1691 aa)
TLR2Toll like receptor 2; Belongs to the Toll-like receptor family. (798 aa)
APAF1Apoptotic peptidase activating factor 1. (1202 aa)
PIK3CBPhosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1077 aa)
PDIA3Protein disulfide-isomerase. (497 aa)
SRSF2Serine and arginine rich splicing factor 2a. (221 aa)
Lach-UA-01Ig-like domain-containing protein; Belongs to the MHC class I family. (280 aa)
PIK3R1Phosphoinositide-3-kinase regulatory subunit 1. (725 aa)
LOC102365315Uncharacterized protein. (642 aa)
TAP2Transporter associated with antigen processing, subunit type a. (720 aa)
TP53Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (401 aa)
TAP1Transporter 1, ATP-binding cassette, sub-family B (MDR/TAP). (735 aa)
SRSF1Serine and arginine rich splicing factor 1a. (266 aa)
NECTIN1Nectin cell adhesion molecule 1. (498 aa)
LOC102347621Uncharacterized protein. (897 aa)
LOC102350366TIR domain-containing protein. (789 aa)
FASLGFas ligand. (261 aa)
TRADDDeath domain-containing protein. (313 aa)
PPP1CCSerine/threonine-protein phosphatase; Belongs to the PPP phosphatase family. (323 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1069 aa)
LOC106703253Uncharacterized protein. (815 aa)
LOC102354242Uncharacterized protein. (1161 aa)
CD74CD74 molecule. (279 aa)
BAK1BCL2 antagonist/killer 1. (239 aa)
C3Uncharacterized protein. (1286 aa)
MTORMechanistic target of rapamycin kinase; Belongs to the PI3/PI4-kinase family. (1009 aa)
H3BAI7_LATCHTNFR-Cys domain-containing protein. (219 aa)
MYD88Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (286 aa)
TNFSF14TNF_2 domain-containing protein. (238 aa)
TAB2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (691 aa)
EIF2B1Eukaryotic translation initiation factor 2B subunit alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (312 aa)
SOCS3Suppressor of cytokine signaling 3. (205 aa)
NFKBIANuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (298 aa)
LOC102355189Toll-like receptor 18; Belongs to the Toll-like receptor family. (797 aa)
CARD9Caspase recruitment domain family member 9. (567 aa)
SRSF9Serine and arginine rich splicing factor 9. (225 aa)
CALR3Calreticulin. (416 aa)
TLR9Toll-like receptor 9. (1039 aa)
LOC102349599Serine and arginine rich splicing factor 7a. (206 aa)
LOC102360064Uncharacterized protein. (298 aa)
LOC102360854Uncharacterized protein. (210 aa)
TNFRSF14Uncharacterized protein. (274 aa)
RHEBL1Ras homolog, mTORC1 binding like 1. (184 aa)
ZNF91Uncharacterized protein. (496 aa)
AKT3Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (470 aa)
LOC102358583Uncharacterized protein. (304 aa)
M3XJZ2_LATCHUncharacterized protein. (497 aa)
M3XKG1_LATCHUncharacterized protein. (531 aa)
LOC106706379Uncharacterized protein. (714 aa)
LOC102348192Uncharacterized protein. (696 aa)
Your Current Organism:
Latimeria chalumnae
NCBI taxonomy Id: 7897
Other names: L. chalumnae, coelacanth
Server load: low (30%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.