STRINGSTRING
W5LXJ3_LEPOC W5LXJ3_LEPOC mcm6 mcm6 rfc4 rfc4 rfc2 rfc2 gins2 gins2 orc4 orc4 W5M103_LEPOC W5M103_LEPOC cdc45 cdc45 pola1 pola1 pold3 pold3 chtf8 chtf8 pole3 pole3 W5M4G9_LEPOC W5M4G9_LEPOC W5M4I8_LEPOC W5M4I8_LEPOC LOC107079691 LOC107079691 rfc5 rfc5 gins3 gins3 pole4 pole4 pole pole timeless timeless W5M9K5_LEPOC W5M9K5_LEPOC W5M9S6_LEPOC W5M9S6_LEPOC MCMDC2 MCMDC2 W5MBI2_LEPOC W5MBI2_LEPOC cdc7 cdc7 orc6 orc6 chtf18 chtf18 mcm4 mcm4 orc1 orc1 prim1 prim1 recql4 recql4 rfc3 rfc3 W5MPK4_LEPOC W5MPK4_LEPOC dscc1 dscc1 DNA2 DNA2 orc2 orc2 W5MWB9_LEPOC W5MWB9_LEPOC lrr1 lrr1 pole2 pole2 W5N0A7_LEPOC W5N0A7_LEPOC W5N0E7_LEPOC W5N0E7_LEPOC W5N2L8_LEPOC W5N2L8_LEPOC LOC102697986 LOC102697986 rfc1 rfc1 mcm7 mcm7 LOC102695737 LOC102695737 cdc6 cdc6 mcm2 mcm2 W5N8N6_LEPOC W5N8N6_LEPOC W5N8X8_LEPOC W5N8X8_LEPOC pold2 pold2 W5NEJ3_LEPOC W5NEJ3_LEPOC pcna pcna mcm10 mcm10 W5NG96_LEPOC W5NG96_LEPOC gins4 gins4 mcm8 mcm8 W5NIU6_LEPOC W5NIU6_LEPOC gins1 gins1 W5NJX2_LEPOC W5NJX2_LEPOC prim2 prim2 mcm9 mcm9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5LXJ3_LEPOCDNA_pol_B domain-containing protein. (97 aa)
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
rfc4Replication factor C (activator 1) 4. (359 aa)
rfc2Replication factor C (activator 1) 2. (358 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
W5M103_LEPOCDNA ligase. (1030 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
pola1DNA polymerase. (1486 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (125 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa)
W5M4G9_LEPOCDNA_pol_E_B domain-containing protein. (66 aa)
W5M4I8_LEPOCUncharacterized protein. (168 aa)
LOC107079691Chemokine (C-C motif) ligand 44. (115 aa)
rfc5Replication factor C (activator 1) 5. (367 aa)
gins3GINS complex subunit 3. (211 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (135 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2298 aa)
timelessTimeless circadian clock. (1225 aa)
W5M9K5_LEPOCRAD17 checkpoint clamp loader component. (584 aa)
W5M9S6_LEPOCXPGI domain-containing protein. (345 aa)
MCMDC2Minichromosome maintenance domain containing 2. (684 aa)
W5MBI2_LEPOCChromatin licensing and DNA replication factor 1. (614 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (545 aa)
orc6Origin recognition complex, subunit 6. (256 aa)
chtf18CTF18, chromosome transmission fidelity factor 18 homolog (S. cerevisiae). (837 aa)
mcm4DNA helicase; Belongs to the MCM family. (678 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (919 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa)
recql4RecQ helicase-like 4. (1459 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
W5MPK4_LEPOCTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (151 aa)
dscc1DNA replication and sister chromatid cohesion 1. (391 aa)
DNA2DNA replication helicase/nuclease 2. (1397 aa)
orc2Origin recognition complex, subunit 2. (576 aa)
W5MWB9_LEPOCDBF4 zinc finger. (622 aa)
lrr1Zgc:77287. (421 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa)
W5N0A7_LEPOCMinichromosome maintenance complex binding protein. (638 aa)
W5N0E7_LEPOCUncharacterized protein. (315 aa)
W5N2L8_LEPOCWD repeat and HMG-box DNA binding protein 1. (1133 aa)
LOC102697986DNA helicase; Belongs to the MCM family. (814 aa)
rfc1Replication factor C subunit 1. (1204 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa)
LOC102695737DNA helicase; Belongs to the MCM family. (834 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
W5N8N6_LEPOCATPase family AAA domain containing 5a. (1812 aa)
W5N8X8_LEPOCTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (323 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa)
W5NEJ3_LEPOCOrigin recognition complex, subunit 5. (375 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (264 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (867 aa)
W5NG96_LEPOCDNA helicase; Belongs to the MCM family. (815 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (852 aa)
W5NIU6_LEPOCExonuclease 1. (797 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (196 aa)
W5NJX2_LEPOCOrigin recognition complex, subunit 3. (728 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (512 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (660 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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