STRINGSTRING
mcm6 mcm6 orc4 orc4 cdc45 cdc45 W5MBI2_LEPOC W5MBI2_LEPOC orc6 orc6 mcm4 mcm4 orc1 orc1 orc2 orc2 LOC102697986 LOC102697986 mcm7 mcm7 LOC102695737 LOC102695737 cdc6 cdc6 mcm2 mcm2 W5NEJ3_LEPOC W5NEJ3_LEPOC mcm10 mcm10 W5NG96_LEPOC W5NG96_LEPOC mcm8 mcm8 W5NJX2_LEPOC W5NJX2_LEPOC mcm9 mcm9
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
W5MBI2_LEPOCChromatin licensing and DNA replication factor 1. (614 aa)
orc6Origin recognition complex, subunit 6. (256 aa)
mcm4DNA helicase; Belongs to the MCM family. (678 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (919 aa)
orc2Origin recognition complex, subunit 2. (576 aa)
LOC102697986DNA helicase; Belongs to the MCM family. (814 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa)
LOC102695737DNA helicase; Belongs to the MCM family. (834 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
W5NEJ3_LEPOCOrigin recognition complex, subunit 5. (375 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (867 aa)
W5NG96_LEPOCDNA helicase; Belongs to the MCM family. (815 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (852 aa)
W5NJX2_LEPOCOrigin recognition complex, subunit 3. (728 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (660 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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