STRINGSTRING
dbt dbt LOC102684697 LOC102684697 ppp1r32 ppp1r32 LOC102697781 LOC102697781 LOC102683357 LOC102683357 idh3b idh3b pdhx pdhx dlat dlat LOC102689788 LOC102689788 mdh2 mdh2 txnrd2 txnrd2 suclg1 suclg1 ilvbl ilvbl ldhd ldhd pdha1 pdha1 idh1 idh1 cs cs uevld uevld gpt2 gpt2 sdhd sdhd got2 got2 W5MHY8_LEPOC W5MHY8_LEPOC pck1 pck1 W5MLH9_LEPOC W5MLH9_LEPOC W5MM14_LEPOC W5MM14_LEPOC LOC102697165 LOC102697165 W5MRF7_LEPOC W5MRF7_LEPOC got1 got1 W5MSQ5_LEPOC W5MSQ5_LEPOC me3 me3 suclg2 suclg2 mdh1b mdh1b SUCLA2 SUCLA2 W5MX10_LEPOC W5MX10_LEPOC nit2 nit2 dlst dlst W5N0W0_LEPOC W5N0W0_LEPOC l2hgdh l2hgdh RNF138 RNF138 me2 me2 pdhb pdhb txnrd3 txnrd3 bckdha bckdha idh2 idh2 W5NBK6_LEPOC W5NBK6_LEPOC LOC102683593 LOC102683593 idh3a idh3a LOC102689506 LOC102689506 pkm pkm parp6 parp6 OGDH OGDH bcat1 bcat1 ldhb ldhb urb2 urb2 dld dld mdh1 mdh1 fh fh hmgcll1 hmgcll1 bckdhb bckdhb me1 me1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (495 aa)
LOC102684697Uncharacterized protein. (137 aa)
ppp1r32Uncharacterized protein. (153 aa)
LOC102697781L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (333 aa)
LOC102683357Uncharacterized protein. (369 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (390 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (496 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (637 aa)
LOC102689788Succinate dehydrogenase complex, subunit C, integral membrane protein. (107 aa)
mdh2Malate dehydrogenase. (337 aa)
txnrd2Thioredoxin reductase 2, tandem duplicate 1. (398 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (324 aa)
ilvblIlvB (bacterial acetolactate synthase)-like; Belongs to the TPP enzyme family. (630 aa)
ldhdLactate dehydrogenase D. (497 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (395 aa)
idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (464 aa)
csCitrate synthase; Belongs to the citrate synthase family. (468 aa)
uevldL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (336 aa)
gpt2Glutamic pyruvate transaminase (alanine aminotransferase) 2. (555 aa)
sdhdSuccinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (157 aa)
got2Aspartate aminotransferase. (446 aa)
W5MHY8_LEPOCPyruvate kinase; Belongs to the pyruvate kinase family. (452 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (623 aa)
W5MLH9_LEPOCUncharacterized protein. (391 aa)
W5MM14_LEPOCSi:dkey-31b16.7. (246 aa)
LOC102697165Si:ch211-217a12.1. (489 aa)
W5MRF7_LEPOCAminotran_1_2 domain-containing protein. (492 aa)
got1Aspartate aminotransferase. (413 aa)
W5MSQ5_LEPOCSuccinate dehydrogenase complex, subunit A, flavoprotein (Fp). (571 aa)
me3Malic enzyme. (619 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (438 aa)
mdh1bMalate dehydrogenase 1B, NAD (soluble). (468 aa)
SUCLA2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (457 aa)
W5MX10_LEPOCMalate synthase-like. (550 aa)
nit2Nitrilase family, member 2. (285 aa)
dlstDihydrolipoamide S-succinyltransferase. (460 aa)
W5N0W0_LEPOCAconitase 2, mitochondrial. (705 aa)
l2hgdhL-2-hydroxyglutarate dehydrogenase. (423 aa)
RNF138Ring finger protein 138. (239 aa)
me2Malic enzyme. (583 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
txnrd3Thioredoxin reductase 3. (637 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (382 aa)
idh2Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (451 aa)
W5NBK6_LEPOCIsocitrate dehydrogenase (NAD(+)) 3 gamma. (380 aa)
LOC102683593Zgc:113208. (162 aa)
idh3aIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (368 aa)
LOC102689506Glutamic-oxaloacetic transaminase 1 like 1. (413 aa)
pkmPyruvate kinase; Belongs to the pyruvate kinase family. (554 aa)
parp6Poly [ADP-ribose] polymerase. (650 aa)
OGDHOxoglutarate dehydrogenase. (1003 aa)
bcat1Branched-chain-amino-acid aminotransferase; Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family. (400 aa)
ldhbL-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (335 aa)
urb2URB2 ribosome biogenesis homolog. (1533 aa)
dldDihydrolipoyl dehydrogenase. (533 aa)
mdh1Malate dehydrogenase. (350 aa)
fhFumarate hydratase. (506 aa)
hmgcll13-hydroxymethyl-3-methylglutaryl-CoA lyase-like 1. (335 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (393 aa)
me1Malic enzyme. (588 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.