(16 nodes) CBM21 domain superfamily, and Prenylation network (Lepisosteus oculatus)

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second shell of interactors

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Your Input:
	W5M566_LEPOC	Protein phosphatase 1, regulatory subunit 15B. (488 aa)
	LOC102688966	Phosphorylase kinase, gamma 2 (testis). (156 aa)
	phkg1	Phosphorylase kinase, gamma 1b (muscle); Belongs to the protein kinase superfamily. (393 aa)
	phkb	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1114 aa)
	LRRC43	Leucine rich repeat containing 43. (644 aa)
	ppp1r3c	Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown. (320 aa)
	phka2	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family. (1265 aa)
	ppp1r3g	Si:ch211-152c8.5. (236 aa)
	W5NAU5_LEPOC	CBM21 domain-containing protein. (295 aa)
	hdac8	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. (1381 aa)
	BMT2	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...] (408 aa)
	W5NG59_LEPOC	CBM21 domain-containing protein. (1012 aa)
	LOC102689970	Zgc:77112. (313 aa)
	W5NLZ3_LEPOC	Protein phosphatase 1 regulatory subunit. (305 aa)
	W5NM29_LEPOC	CBM21 domain-containing protein. (301 aa)
	ppp1r3d	Protein phosphatase 1, regulatory subunit 3Db. (268 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
BMT2	LOC102688966	ENSLOCP00000019617	ENSLOCP00000003946	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Phosphorylase kinase, gamma 2 (testis).	0.450
BMT2	W5NLZ3_LEPOC	ENSLOCP00000019617	ENSLOCP00000021652	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Protein phosphatase 1 regulatory subunit.	0.867
BMT2	W5NM29_LEPOC	ENSLOCP00000019617	ENSLOCP00000021688	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	CBM21 domain-containing protein.	0.733
BMT2	hdac8	ENSLOCP00000019617	ENSLOCP00000017801	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	0.860
BMT2	phka2	ENSLOCP00000019617	ENSLOCP00000009064	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.	0.862
BMT2	phkb	ENSLOCP00000019617	ENSLOCP00000006421	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	0.862
BMT2	phkg1	ENSLOCP00000019617	ENSLOCP00000005056	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Phosphorylase kinase, gamma 1b (muscle); Belongs to the protein kinase superfamily.	0.883
BMT2	ppp1r3c	ENSLOCP00000019617	ENSLOCP00000007257	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.	0.862
BMT2	ppp1r3d	ENSLOCP00000019617	ENSLOCP00000022460	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Protein phosphatase 1, regulatory subunit 3Db.	0.733
BMT2	ppp1r3g	ENSLOCP00000019617	ENSLOCP00000014321	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	Si:ch211-152c8.5.	0.557
LOC102688966	BMT2	ENSLOCP00000003946	ENSLOCP00000019617	Phosphorylase kinase, gamma 2 (testis).	S-adenosylmethionine sensor upstream of mTORC1; S-adenosyl-L-methionine-binding protein that acts as an inhibitor of mTORC1 signaling via interaction with the GATOR1 and KICSTOR complexes. Acts as a sensor of S-adenosyl-L-methionine to signal methionine sufficiency to mTORC1: in presence of methionine, binds S-adenosyl-L-methionine, leading to disrupt interaction with the GATOR1 and KICSTOR complexes and promote mTORC1 signaling. Upon methionine starvation, S-adenosyl-L-methionine levels are reduced, thereby promoting the association with GATOR1 and KICSTOR, leading to inhibit mTORC1 s [...]	0.450
LOC102688966	LOC102689970	ENSLOCP00000003946	ENSLOCP00000019819	Phosphorylase kinase, gamma 2 (testis).	Zgc:77112.	0.450
LOC102688966	W5NAU5_LEPOC	ENSLOCP00000003946	ENSLOCP00000017754	Phosphorylase kinase, gamma 2 (testis).	CBM21 domain-containing protein.	0.450
LOC102688966	W5NG59_LEPOC	ENSLOCP00000003946	ENSLOCP00000019618	Phosphorylase kinase, gamma 2 (testis).	CBM21 domain-containing protein.	0.450
LOC102688966	W5NLZ3_LEPOC	ENSLOCP00000003946	ENSLOCP00000021652	Phosphorylase kinase, gamma 2 (testis).	Protein phosphatase 1 regulatory subunit.	0.450
LOC102688966	W5NM29_LEPOC	ENSLOCP00000003946	ENSLOCP00000021688	Phosphorylase kinase, gamma 2 (testis).	CBM21 domain-containing protein.	0.450
LOC102688966	hdac8	ENSLOCP00000003946	ENSLOCP00000017801	Phosphorylase kinase, gamma 2 (testis).	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	0.899
LOC102688966	phka2	ENSLOCP00000003946	ENSLOCP00000009064	Phosphorylase kinase, gamma 2 (testis).	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I. Belongs to the phosphorylase b kinase regulatory chain family.	0.899
LOC102688966	phkb	ENSLOCP00000003946	ENSLOCP00000006421	Phosphorylase kinase, gamma 2 (testis).	Phosphorylase b kinase regulatory subunit; Phosphorylase b kinase catalyzes the phosphorylation of serine in certain substrates, including troponin I.	0.899
LOC102688966	ppp1r3c	ENSLOCP00000003946	ENSLOCP00000007257	Phosphorylase kinase, gamma 2 (testis).	Protein phosphatase 1 regulatory subunit 3C; Acts as a glycogen-targeting subunit for PP1 and regulates its activity. Activates glycogen synthase, reduces glycogen phosphorylase activity and limits glycogen breakdown.	0.450