68 items (Lepisosteus oculatus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	W5LX59_LEPOC	DMPK_coil domain-containing protein. (110 aa)
	TRIO	Trio Rho guanine nucleotide exchange factor a. (3221 aa)
	cdc42	Cell division cycle 42. (195 aa)
	rnd3	Rho family GTPase 3b. (243 aa)
	prex1	Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 1. (1636 aa)
	W5M0C9_LEPOC	Citron rho-interacting serine/threonine kinase a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2023 aa)
	PFN2	Profilin; Belongs to the profilin family. (173 aa)
	W5M213_LEPOC	Rho guanine nucleotide exchange factor (GEF) 12b. (1364 aa)
	ARHGEF26	Rho guanine nucleotide exchange factor 26. (884 aa)
	LOC107079539	FH2 domain-containing protein. (830 aa)
	W5M828_LEPOC	PH domain-containing protein. (850 aa)
	W5M916_LEPOC	Formin-like 3. (934 aa)
	myo9b	Myosin IXb; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2130 aa)
	git2	G protein-coupled receptor kinase interacting ArfGAP 2a. (779 aa)
	prex2	Phosphatidylinositol-3,4,5-trisphosphate-dependent Rac exchange factor 2. (1606 aa)
	W5MAC9_LEPOC	Rho guanine nucleotide exchange factor (GEF) 1b. (970 aa)
	SPATA13	Spermatogenesis associated 13. (1211 aa)
	vav2	Vav 2 guanine nucleotide exchange factor. (879 aa)
	diaph3	Diaphanous-related formin 3. (956 aa)
	rhof	Ras homolog family member F. (215 aa)
	W5MDZ1_LEPOC	Kalirin RhoGEF kinase a. (3026 aa)
	W5ME91_LEPOC	IQ motif containing GTPase activating protein 2. (1619 aa)
	pak2	Non-specific serine/threonine protein kinase. (529 aa)
	fmnl2	Formin-like 2a. (1088 aa)
	W5MEU0_LEPOC	Rho GTPase activating protein 1. (423 aa)
	W5MGH2_LEPOC	Uncharacterized protein. (203 aa)
	arhgdig	Rho GDP dissociation inhibitor (GDI) gamma. (224 aa)
	W5MHQ5_LEPOC	G protein-coupled receptor kinase interacting ArfGAP 1. (582 aa)
	pak1	Non-specific serine/threonine protein kinase. (551 aa)
	anln	Anillin, actin binding protein. (1217 aa)
	rnd1	Rho family GTPase 1a. (232 aa)
	W5MKQ6_LEPOC	Uncharacterized protein. (384 aa)
	LOC102698253	Cell division cycle 42, like. (191 aa)
	ARHGEF25	DH domain-containing protein. (562 aa)
	nck1	Cytoplasmic protein. (380 aa)
	rac1	Rac family small GTPase 1b. (195 aa)
	W5MPP8_LEPOC	FH2 domain containing 1. (1131 aa)
	LOC102693786	IQ motif containing GTPase activating protein 3. (1659 aa)
	nck2	Cytoplasmic protein. (381 aa)
	arhgef7	Rho guanine nucleotide exchange factor (GEF) 7a. (862 aa)
	tiam1	T cell lymphoma invasion and metastasis 1a. (1592 aa)
	W5MSI1_LEPOC	Dishevelled associated activator of morphogenesis 1a. (1077 aa)
	ARHGEF4	Rho guanine nucleotide exchange factor 4. (634 aa)
	gem	GTP binding protein overexpressed in skeletal muscle. (240 aa)
	rhoj	Ras homolog family member J. (223 aa)
	DIAPH1	Diaphanous related formin 1. (1243 aa)
	W5N1V6_LEPOC	Formin-like 1a. (1081 aa)
	rhov	Ras homolog family member V. (244 aa)
	RAC3	Rac family small GTPase 3. (192 aa)
	pak6	Non-specific serine/threonine protein kinase. (683 aa)
	PAK3	Non-specific serine/threonine protein kinase. (580 aa)
	arhgdia	Rho GDP dissociation inhibitor (GDI) alpha. (234 aa)
	rasl12	RAS-like, family 12. (260 aa)
	iqgap1	IQ motif containing GTPase activating protein 1. (1656 aa)
	W5NAN1_LEPOC	Non-specific serine/threonine protein kinase. (718 aa)
	W5NCC0_LEPOC	FH2 domain-containing protein. (735 aa)
	W5NCH2_LEPOC	Ras homolog family member Ub. (304 aa)
	myo9a	Myosin IXAa; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. (2677 aa)
	arhgef6	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (783 aa)
	W5NE24_LEPOC	Diaphanous-related formin 2. (1000 aa)
	rhou	Ras homolog family member Ua. (253 aa)
	rhoq	Ras homolog family member Q. (207 aa)
	pak5	Non-specific serine/threonine protein kinase. (749 aa)
	W5NJM5_LEPOC	T cell lymphoma invasion and metastasis 2a. (1734 aa)
	daam2	Dishevelled associated activator of morphogenesis 2. (1088 aa)
	LOC102690743	Ras homolog gene family, member Gc. (191 aa)
	diras1	DIRAS family, GTP-binding RAS-like 1b. (198 aa)
	rhob	Uncharacterized protein. (196 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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structured XML interaction data, according to the 'PSI-MI' data standard

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a flat-file format describing the coordinates and colors of nodes in the network

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ARHGEF25	LOC102690743	ENSLOCP00000009210	ENSLOCP00000021588	DH domain-containing protein.	Ras homolog gene family, member Gc.	0.808
ARHGEF25	LOC102698253	ENSLOCP00000009210	ENSLOCP00000008990	DH domain-containing protein.	Cell division cycle 42, like.	0.808
ARHGEF25	PAK3	ENSLOCP00000009210	ENSLOCP00000017065	DH domain-containing protein.	Non-specific serine/threonine protein kinase.	0.593
ARHGEF25	RAC3	ENSLOCP00000009210	ENSLOCP00000015230	DH domain-containing protein.	Rac family small GTPase 3.	0.808
ARHGEF25	W5LX59_LEPOC	ENSLOCP00000009210	ENSLOCP00000000716	DH domain-containing protein.	DMPK_coil domain-containing protein.	0.433
ARHGEF25	W5M213_LEPOC	ENSLOCP00000009210	ENSLOCP00000002421	DH domain-containing protein.	Rho guanine nucleotide exchange factor (GEF) 12b.	0.446
ARHGEF25	W5MAC9_LEPOC	ENSLOCP00000009210	ENSLOCP00000005338	DH domain-containing protein.	Rho guanine nucleotide exchange factor (GEF) 1b.	0.446
ARHGEF25	W5MHQ5_LEPOC	ENSLOCP00000009210	ENSLOCP00000007914	DH domain-containing protein.	G protein-coupled receptor kinase interacting ArfGAP 1.	0.452
ARHGEF25	W5MKQ6_LEPOC	ENSLOCP00000009210	ENSLOCP00000008965	DH domain-containing protein.	Uncharacterized protein.	0.404
ARHGEF25	W5NAN1_LEPOC	ENSLOCP00000009210	ENSLOCP00000017690	DH domain-containing protein.	Non-specific serine/threonine protein kinase.	0.590
ARHGEF25	W5NCH2_LEPOC	ENSLOCP00000009210	ENSLOCP00000018331	DH domain-containing protein.	Ras homolog family member Ub.	0.808
ARHGEF25	arhgef6	ENSLOCP00000009210	ENSLOCP00000018632	DH domain-containing protein.	Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6.	0.404
ARHGEF25	arhgef7	ENSLOCP00000009210	ENSLOCP00000011096	DH domain-containing protein.	Rho guanine nucleotide exchange factor (GEF) 7a.	0.404
ARHGEF25	cdc42	ENSLOCP00000009210	ENSLOCP00000001212	DH domain-containing protein.	Cell division cycle 42.	0.808
ARHGEF25	diras1	ENSLOCP00000009210	ENSLOCP00000021731	DH domain-containing protein.	DIRAS family, GTP-binding RAS-like 1b.	0.621
ARHGEF25	gem	ENSLOCP00000009210	ENSLOCP00000012378	DH domain-containing protein.	GTP binding protein overexpressed in skeletal muscle.	0.621
ARHGEF25	git2	ENSLOCP00000009210	ENSLOCP00000005007	DH domain-containing protein.	G protein-coupled receptor kinase interacting ArfGAP 2a.	0.452
ARHGEF25	nck1	ENSLOCP00000009210	ENSLOCP00000009233	DH domain-containing protein.	Cytoplasmic protein.	0.594
ARHGEF25	nck2	ENSLOCP00000009210	ENSLOCP00000010689	DH domain-containing protein.	Cytoplasmic protein.	0.594
ARHGEF25	pak1	ENSLOCP00000009210	ENSLOCP00000007920	DH domain-containing protein.	Non-specific serine/threonine protein kinase.	0.593