STRINGSTRING
mus81 mus81 mcm6 mcm6 gins2 gins2 ap5s1 ap5s1 W5LZC5_LEPOC W5LZC5_LEPOC W5LZK6_LEPOC W5LZK6_LEPOC rfwd3 rfwd3 RBBP8 RBBP8 cdc45 cdc45 rad51d rad51d W5M4D7_LEPOC W5M4D7_LEPOC ANKLE1 ANKLE1 W5M661_LEPOC W5M661_LEPOC W5M730_LEPOC W5M730_LEPOC W5M8B8_LEPOC W5M8B8_LEPOC nsmce1 nsmce1 rmi2 rmi2 W5MA42_LEPOC W5MA42_LEPOC W5MA78_LEPOC W5MA78_LEPOC ap5z1 ap5z1 nabp2 nabp2 MCMDC2 MCMDC2 cdc7 cdc7 top3a top3a meiob meiob W5MCR9_LEPOC W5MCR9_LEPOC W5MEE1_LEPOC W5MEE1_LEPOC W5MEG4_LEPOC W5MEG4_LEPOC xrcc1 xrcc1 tonsl tonsl W5MFP6_LEPOC W5MFP6_LEPOC mcm4 mcm4 SPIDR SPIDR rpa1 rpa1 recql4 recql4 ercc4 ercc4 mre11 mre11 swsap1 swsap1 W5MNK3_LEPOC W5MNK3_LEPOC psmd14 psmd14 smc5 smc5 wdr48 wdr48 W5MUV7_LEPOC W5MUV7_LEPOC NSMCE2 NSMCE2 fancb fancb W5MW35_LEPOC W5MW35_LEPOC W5MXW8_LEPOC W5MXW8_LEPOC sem1 sem1 rpa3 rpa3 FANCM FANCM W5N048_LEPOC W5N048_LEPOC recql5 recql5 poll poll dmc1 dmc1 helq helq LOC102697986 LOC102697986 RNF138 RNF138 ino80 ino80 XRCC2 XRCC2 rad51 rad51 W5N4U2_LEPOC W5N4U2_LEPOC mcm7 mcm7 LOC102696624 LOC102696624 LOC102695737 LOC102695737 HUS1 HUS1 exd2 exd2 mcm2 mcm2 W5N8A0_LEPOC W5N8A0_LEPOC rad51b rad51b W5NA08_LEPOC W5NA08_LEPOC blm blm W5NE81_LEPOC W5NE81_LEPOC W5NF63_LEPOC W5NF63_LEPOC W5NG96_LEPOC W5NG96_LEPOC gins4 gins4 mcm8 mcm8 W5NK42_LEPOC W5NK42_LEPOC W5NK63_LEPOC W5NK63_LEPOC W5NK64_LEPOC W5NK64_LEPOC mms22l mms22l GEN1 GEN1 mcm9 mcm9 rmi1 rmi1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mus81MUS81 structure-specific endonuclease subunit. (616 aa)
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
ap5s1Adaptor related protein complex 5 subunit sigma 1. (206 aa)
W5LZC5_LEPOCRAD51 paralog C. (374 aa)
W5LZK6_LEPOCNon-specific serine/threonine protein kinase. (3061 aa)
rfwd3Ring finger and WD repeat domain 3. (727 aa)
RBBP8Uncharacterized protein. (865 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
rad51dDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA breaks arising during DNA replication or induced by DNA-damaging agents; Belongs to the RecA family. RAD51 subfamily. (336 aa)
W5M4D7_LEPOCSLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1669 aa)
ANKLE1Ankyrin repeat and LEM domain containing 1. (986 aa)
W5M661_LEPOCRAD21 cohesin complex component a. (645 aa)
W5M730_LEPOCZinc finger, SWIM-type containing 7. (147 aa)
W5M8B8_LEPOCUncharacterized protein. (326 aa)
nsmce1NSE1 homolog, SMC5-SMC6 complex component. (276 aa)
rmi2RecQ mediated genome instability 2. (154 aa)
W5MA42_LEPOCSAM domain and HD domain 1. (617 aa)
W5MA78_LEPOCHD domain-containing protein. (411 aa)
ap5z1Adaptor related protein complex 5 subunit zeta 1. (1529 aa)
nabp2Nucleic acid binding protein 2. (206 aa)
MCMDC2Minichromosome maintenance domain containing 2. (684 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (545 aa)
top3aDNA topoisomerase; Introduces a single-strand break via transesterification at a target site in duplex DNA. Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. Belongs to the type IA topoisomerase family. (803 aa)
meiobMethionine sulfoxide reductase B1b. (471 aa)
W5MCR9_LEPOCNucleic acid binding protein 1a. (223 aa)
W5MEE1_LEPOCPALB2_WD40 domain-containing protein. (122 aa)
W5MEG4_LEPOCUncharacterized protein. (536 aa)
xrcc1X-ray repair complementing defective repair in Chinese hamster cells 1. (648 aa)
tonslTonsoku-like, DNA repair protein. (1444 aa)
W5MFP6_LEPOCRAD21 cohesin complex component like 1. (596 aa)
mcm4DNA helicase; Belongs to the MCM family. (678 aa)
SPIDRScaffold protein involved in DNA repair. (961 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
recql4RecQ helicase-like 4. (1459 aa)
ercc4Excision repair cross-complementation group 4. (637 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (725 aa)
swsap1SWIM-type zinc finger 7 associated protein 1. (279 aa)
W5MNK3_LEPOCTower domain-containing protein. (871 aa)
psmd14Proteasome 26S subunit, non-ATPase 14. (310 aa)
smc5Structural maintenance of chromosomes 5. (1081 aa)
wdr48WD repeat domain 48b. (679 aa)
W5MUV7_LEPOCDNA repair protein; Involved in the homologous recombination repair (HRR) pathway of double-stranded DNA, thought to repair chromosomal fragmentation, translocations and deletions; Belongs to the RecA family. RAD51 subfamily. (348 aa)
NSMCE2NSE2 (MMS21) homolog, SMC5-SMC6 complex SUMO ligase. (251 aa)
fancbFA complementation group B. (834 aa)
W5MW35_LEPOCNibrin. (846 aa)
W5MXW8_LEPOCWRN RecQ like helicase. (1464 aa)
sem1SEM1 26S proteasome complex subunit. (70 aa)
rpa3Replication protein A3. (121 aa)
FANCMFA complementation group M. (2093 aa)
W5N048_LEPOCUncharacterized protein. (1423 aa)
recql5RecQ helicase-like 5. (1025 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (579 aa)
dmc1Uncharacterized protein. (94 aa)
helqHelicase, POLQ like. (1066 aa)
LOC102697986DNA helicase; Belongs to the MCM family. (814 aa)
RNF138Ring finger protein 138. (239 aa)
ino80INO80 complex ATPase subunit. (1554 aa)
XRCC2X-ray repair cross complementing 2. (285 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (341 aa)
W5N4U2_LEPOCNipped-B protein. (2915 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa)
LOC102696624Structure-specific endonuclease subunit SLX1; Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA. (264 aa)
LOC102695737DNA helicase; Belongs to the MCM family. (834 aa)
HUS1Checkpoint protein; Belongs to the HUS1 family. (285 aa)
exd2Exonuclease 3'-5' domain containing 2. (613 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
W5N8A0_LEPOCFanconi-associated nuclease; Nuclease required for the repair of DNA interstrand cross- links (ICL). Acts as a 5'-3' exonuclease that anchors at a cut end of DNA and cleaves DNA successively at every third nucleotide, allowing to excise an ICL from one strand through flanking incisions. Belongs to the FAN1 family. (1018 aa)
rad51bRAD51 paralog B. (384 aa)
W5NA08_LEPOCZinc finger, FYVE domain containing 26. (2545 aa)
blmBLM RecQ like helicase. (1481 aa)
W5NE81_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (636 aa)
W5NF63_LEPOCF-box DNA helicase 1. (1007 aa)
W5NG96_LEPOCDNA helicase; Belongs to the MCM family. (815 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa)
mcm8Minichromosome maintenance 8 homologous recombination repair factor; Belongs to the MCM family. (852 aa)
W5NK42_LEPOCREV3 like, DNA directed polymerase zeta catalytic subunit. (3084 aa)
W5NK63_LEPOCUncharacterized protein. (163 aa)
W5NK64_LEPOCUncharacterized protein. (133 aa)
mms22lMMS22-like, DNA repair protein. (1238 aa)
GEN1GEN1 Holliday junction 5' flap endonuclease. (461 aa)
mcm9Minichromosome maintenance 9 homologous recombination repair factor; Belongs to the MCM family. (660 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (627 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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