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MCMDC2 MCMDC2 gins4 gins4 W5NG96_LEPOC W5NG96_LEPOC mcm2 mcm2 LOC102695737 LOC102695737 mcm7 mcm7 LOC102697986 LOC102697986 mcm4 mcm4 cdc7 cdc7 cdc45 cdc45 gins2 gins2 mcm6 mcm6 mus81 mus81
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
MCMDC2Minichromosome maintenance domain containing 2. (684 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa)
W5NG96_LEPOCDNA helicase; Belongs to the MCM family. (815 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
LOC102695737DNA helicase; Belongs to the MCM family. (834 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa)
LOC102697986DNA helicase; Belongs to the MCM family. (814 aa)
mcm4DNA helicase; Belongs to the MCM family. (678 aa)
cdc7Cell division cycle 7 homolog (S. cerevisiae). (545 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
mus81MUS81 structure-specific endonuclease subunit. (616 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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