STRINGSTRING
EREG EREG fermt2 fermt2 lef1 lef1 mttp mttp W5N3N8_LEPOC W5N3N8_LEPOC HAND1 HAND1 mmrn2 mmrn2 W5N4A3_LEPOC W5N4A3_LEPOC W5N4A9_LEPOC W5N4A9_LEPOC med1 med1 LOC102694927 LOC102694927 cemip cemip plxdc1 plxdc1 LOC102699081 LOC102699081 W5N848_LEPOC W5N848_LEPOC amot amot plekhh1 plekhh1 wnt7a wnt7a serpine1 serpine1 kdr kdr wnt5a wnt5a cspg4 cspg4 W5NAL6_LEPOC W5NAL6_LEPOC LOC102696830 LOC102696830 LOC102690202 LOC102690202 adgra2 adgra2 cib1 cib1 W5NDL9_LEPOC W5NDL9_LEPOC apln apln tgfa tgfa elk3 elk3 wnt7b wnt7b ccn2 ccn2 W5NJP3_LEPOC W5NJP3_LEPOC W5NJI3_LEPOC W5NJI3_LEPOC adm2 adm2 wnt5b wnt5b LOC102695612 LOC102695612 rspo3 rspo3 epas1 epas1 e2f7 e2f7 tcf21 tcf21 ppp3r1 ppp3r1 vegfa vegfa ism1 ism1 srf srf tspan12 tspan12 pik3cg pik3cg LOC102685279 LOC102685279 LOC102689161 LOC102689161 gja5 gja5 TMEM100 TMEM100 jun jun W5NMF6_LEPOC W5NMF6_LEPOC s1pr1 s1pr1 nrarp nrarp ptk2b ptk2b W5NKX8_LEPOC W5NKX8_LEPOC W5LW37_LEPOC W5LW37_LEPOC LOC102694913 LOC102694913 W5LWJ3_LEPOC W5LWJ3_LEPOC LOC102690042 LOC102690042 LOC102687734 LOC102687734 nrp1 nrp1 nus1 nus1 W5LXY0_LEPOC W5LXY0_LEPOC vash2 vash2 foxf1 foxf1 W5M0H1_LEPOC W5M0H1_LEPOC W5M0L9_LEPOC W5M0L9_LEPOC W5M175_LEPOC W5M175_LEPOC LOC102686735 LOC102686735 cdh13 cdh13 tgfbr2 tgfbr2 W5M2Y5_LEPOC W5M2Y5_LEPOC EIF3I EIF3I tbx20 tbx20 W5M3L0_LEPOC W5M3L0_LEPOC W5M3M0_LEPOC W5M3M0_LEPOC angptl4 angptl4 fgf2 fgf2 znrf3 znrf3 W5M5R8_LEPOC W5M5R8_LEPOC angpt1 angpt1 W5M5U9_LEPOC W5M5U9_LEPOC W5M609_LEPOC W5M609_LEPOC pdcd10 pdcd10 sat1 sat1 notch1 notch1 W5M801_LEPOC W5M801_LEPOC W5M865_LEPOC W5M865_LEPOC gdf2 gdf2 mydgf mydgf scg2 scg2 W5M916_LEPOC W5M916_LEPOC vstm4 vstm4 RAMP1 RAMP1 flt1 flt1 glul glul W5MAJ1_LEPOC W5MAJ1_LEPOC W5MBC0_LEPOC W5MBC0_LEPOC gbx2 gbx2 W5MBP2_LEPOC W5MBP2_LEPOC ackr3 ackr3 htatip2 htatip2 W5MC45_LEPOC W5MC45_LEPOC W5MCA6_LEPOC W5MCA6_LEPOC pald1 pald1 bcas3 bcas3 ciao3 ciao3 amotl2 amotl2 rapgef3 rapgef3 ccn1 ccn1 sox18 sox18 SETD2 SETD2 sox17 sox17 pofut1 pofut1 ACVR1 ACVR1 PXDNL PXDNL W5MFN8_LEPOC W5MFN8_LEPOC W5MG35_LEPOC W5MG35_LEPOC calcrl calcrl tie1 tie1 W5MI66_LEPOC W5MI66_LEPOC LOC102687451 LOC102687451 W5MIY9_LEPOC W5MIY9_LEPOC LOC102687202 LOC102687202 HHEX HHEX W5MKA8_LEPOC W5MKA8_LEPOC W5MKZ3_LEPOC W5MKZ3_LEPOC W5ML64_LEPOC W5ML64_LEPOC AMOTL1 AMOTL1 W5MLI6_LEPOC W5MLI6_LEPOC W5MLW0_LEPOC W5MLW0_LEPOC W5MM29_LEPOC W5MM29_LEPOC W5MM76_LEPOC W5MM76_LEPOC ADTRP ADTRP edn1 edn1 epha2 epha2 ATP5F1B ATP5F1B sfrp2 sfrp2 ednra ednra W5MQX3_LEPOC W5MQX3_LEPOC W5MRF2_LEPOC W5MRF2_LEPOC CCN3 CCN3 aamp aamp igfbp2 igfbp2 W5MSP5_LEPOC W5MSP5_LEPOC eif2ak3 eif2ak3 cemip2 cemip2 smarcal1 smarcal1 W5MTX8_LEPOC W5MTX8_LEPOC ndnf ndnf LOC102687572 LOC102687572 prok2 prok2 W5MV98_LEPOC W5MV98_LEPOC HIF1A HIF1A prkx prkx FGF1 FGF1 PDCL3 PDCL3 krit1 krit1 VASH1 VASH1 W5MXD5_LEPOC W5MXD5_LEPOC reck reck plxdc2 plxdc2 W5MYV5_LEPOC W5MYV5_LEPOC C1GALT1 C1GALT1 efnb2 efnb2 pdgfrb pdgfrb W5MZC6_LEPOC W5MZC6_LEPOC jmjd6 jmjd6 sirt1 sirt1 meox2 meox2 otulin otulin klf5 klf5 wars1 wars1 prok1 prok1 enpep enpep W5N1S7_LEPOC W5N1S7_LEPOC ccbe1 ccbe1 esm1 esm1 flt4 flt4 arhgap24 arhgap24 EPGN EPGN
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
EREGEpiregulin. (153 aa)
fermt2Fermitin family member 2. (696 aa)
lef1Lymphoid enhancer-binding factor 1. (397 aa)
mttpMicrosomal triglyceride transfer protein. (889 aa)
W5N3N8_LEPOCReceptor (G protein-coupled) activity modifying protein 2. (163 aa)
HAND1Heart and neural crest derivatives expressed 1. (191 aa)
mmrn2Multimerin 2a. (989 aa)
W5N4A3_LEPOCSeryl-tRNA synthetase. (518 aa)
W5N4A9_LEPOCUncharacterized protein. (369 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1734 aa)
LOC102694927G8 domain-containing protein. (1277 aa)
cemipCell migration inducing hyaluronidase 1. (1361 aa)
plxdc1Plexin domain containing 1. (492 aa)
LOC102699081Si:rp71-17i16.5; Belongs to the PI3/PI4-kinase family. (1091 aa)
W5N848_LEPOCVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (441 aa)
amotAngiomotin. (918 aa)
plekhh1Pleckstrin homology domain containing, family H (with MyTH4 domain) member 1. (1480 aa)
wnt7aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (349 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (391 aa)
kdrKinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1359 aa)
wnt5aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (383 aa)
cspg4Chondroitin sulfate proteoglycan 4. (2307 aa)
W5NAL6_LEPOCHypoxia inducible factor 1 subunit alpha, like. (630 aa)
LOC102696830Uncharacterized protein. (385 aa)
LOC102690202Kruppel-like factor 5 like. (407 aa)
adgra2Adhesion G protein-coupled receptor A2; Belongs to the G-protein coupled receptor 2 family. (1381 aa)
cib1Calcium and integrin binding 1 (calmyrin). (189 aa)
W5NDL9_LEPOCKinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1361 aa)
aplnApelin. (77 aa)
tgfaTransforming growth factor, alpha. (167 aa)
elk3ETS transcription factor ELK3. (422 aa)
wnt7bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (354 aa)
ccn2Cellular communication network factor 2a. (353 aa)
W5NJP3_LEPOCAngiopoietin 2a. (532 aa)
W5NJI3_LEPOCIntegrin beta 1 binding protein 1. (201 aa)
adm2Adrenomedullin 2b. (170 aa)
wnt5bProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (385 aa)
LOC102695612Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (534 aa)
rspo3R-spondin 3. (327 aa)
epas1Endothelial PAS domain protein 1b. (852 aa)
e2f7E2F transcription factor 7. (916 aa)
tcf21Transcription factor 21. (179 aa)
ppp3r1Protein phosphatase 3, regulatory subunit B, alpha a. (169 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (253 aa)
ism1Isthmin 1. (462 aa)
srfSerum response factor b. (605 aa)
tspan12Tetraspanin. (305 aa)
pik3cgPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma; Belongs to the PI3/PI4-kinase family. (1105 aa)
LOC102685279Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (359 aa)
LOC102689161JunE proto-oncogene, AP-1 transcription factor subunit. (349 aa)
gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (357 aa)
TMEM100Transmembrane protein 100. (113 aa)
junJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (322 aa)
W5NMF6_LEPOCCytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (528 aa)
s1pr1Sphingosine-1-phosphate receptor 1; Belongs to the G-protein coupled receptor 1 family. (379 aa)
nrarpNOTCH regulated ankyrin repeat protein a. (112 aa)
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1004 aa)
W5NKX8_LEPOCPeroxidasin. (1498 aa)
W5LW37_LEPOCRas-GAP domain-containing protein. (183 aa)
LOC102694913Uncharacterized protein. (319 aa)
W5LWJ3_LEPOCFrizzled class receptor 8a; Belongs to the G-protein coupled receptor Fz/Smo family. (584 aa)
LOC102690042Uncharacterized protein. (1862 aa)
LOC102687734Uncharacterized protein. (2145 aa)
nrp1Neuropilin; Belongs to the neuropilin family. (924 aa)
nus1NUS1 dehydrodolichyl diphosphate synthase subunit. (315 aa)
W5LXY0_LEPOCCaldesmon 1b. (763 aa)
vash2Vasohibin 2. (369 aa)
foxf1Forkhead box F1. (381 aa)
W5M0H1_LEPOCPAS domain-containing protein. (197 aa)
W5M0L9_LEPOCUncharacterized protein. (302 aa)
W5M175_LEPOCMindbomb E3 ubiquitin protein ligase 1. (1009 aa)
LOC102686735Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
cdh13Cadherin 13, H-cadherin (heart). (714 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)
W5M2Y5_LEPOCStromal cell derived factor 4. (271 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (323 aa)
tbx20T-box transcription factor 20. (461 aa)
W5M3L0_LEPOCApolipoprotein L, 1. (239 aa)
W5M3M0_LEPOCBMP binding endothelial regulator. (644 aa)
angptl4Angiopoietin-like 4. (469 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (167 aa)
znrf3Zinc and ring finger 3. (889 aa)
W5M5R8_LEPOCX-box binding protein 1. (385 aa)
angpt1Angiopoietin 1. (506 aa)
W5M5U9_LEPOCTEK tyrosine kinase, endothelial. (1116 aa)
W5M609_LEPOCSi:dkey-206d17.12. (622 aa)
pdcd10Programmed cell death 10b. (212 aa)
sat1Spermidine/spermine N1-acetyltransferase 1b. (175 aa)
notch1Notch receptor 1a. (2542 aa)
W5M801_LEPOCUncharacterized protein. (222 aa)
W5M865_LEPOCVWFA domain-containing protein. (1637 aa)
gdf2Growth differentiation factor 2. (411 aa)
mydgfMyeloid-derived growth factor. (164 aa)
scg2Secretogranin II (chromogranin C), b. (613 aa)
W5M916_LEPOCFormin-like 3. (934 aa)
vstm4V-set and transmembrane domain containing 4a. (332 aa)
RAMP1Receptor activity modifying protein 1. (198 aa)
flt1Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1340 aa)
glulGlutamine synthetase. (376 aa)
W5MAJ1_LEPOCChemokine (C-X-C motif) receptor 3, tandem duplicate 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
W5MBC0_LEPOCNeurofibromin 1b. (2820 aa)
gbx2Gastrulation brain homeobox 2. (342 aa)
W5MBP2_LEPOCE2F transcription factor 8. (956 aa)
ackr3Atypical chemokine receptor 3b; Belongs to the G-protein coupled receptor 1 family. (348 aa)
htatip2HIV-1 Tat interactive protein 2. (279 aa)
W5MC45_LEPOCYjeF N-terminal domain containing 3. (194 aa)
W5MCA6_LEPOCUncharacterized protein. (857 aa)
pald1Phosphatase domain containing paladin 1b. (892 aa)
bcas3BCAS3 microtubule associated cell migration factor. (814 aa)
ciao3Nuclear prelamin A recognition factor-like; Belongs to the NARF family. (397 aa)
amotl2Angiomotin like 2b. (728 aa)
rapgef3Rap guanine nucleotide exchange factor (GEF) 3. (877 aa)
ccn1Cellular communication network factor 1. (377 aa)
sox18SRY-box transcription factor 18. (414 aa)
SETD2SET domain containing 2, histone lysine methyltransferase. (2553 aa)
sox17SRY-box transcription factor 17. (391 aa)
pofut1Protein O-fucosyltransferase 1. (393 aa)
ACVR1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (531 aa)
PXDNLPeroxidasin like. (1493 aa)
W5MFN8_LEPOCR-spondin 1. (263 aa)
W5MG35_LEPOCUncharacterized protein. (190 aa)
calcrlCalcitonin receptor-like a; Belongs to the G-protein coupled receptor 2 family. (479 aa)
tie1Tyrosine kinase with immunoglobulin-like and EGF-like domains 1. (1137 aa)
W5MI66_LEPOCRAB13, member RAS oncogene family. (162 aa)
LOC102687451Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (508 aa)
W5MIY9_LEPOCLeptin receptor. (834 aa)
LOC102687202Si:dkey-193c22.2. (2427 aa)
HHEXHematopoietically expressed homeobox. (276 aa)
W5MKA8_LEPOCUncharacterized protein. (172 aa)
W5MKZ3_LEPOCAngiopoietin 4. (505 aa)
W5ML64_LEPOCCore 1 synthase, glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase, 1a. (347 aa)
AMOTL1Angiomotin like 1. (996 aa)
W5MLI6_LEPOCReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (459 aa)
W5MLW0_LEPOCProtein tyrosine kinase 2aa. (1079 aa)
W5MM29_LEPOCVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (311 aa)
W5MM76_LEPOCUncharacterized protein. (307 aa)
ADTRPAndrogen dependent TFPI regulating protein. (236 aa)
edn1Endothelin 1. (200 aa)
epha2Eph receptor A2 b. (980 aa)
ATP5F1BATP synthase subunit beta; Produces ATP from ADP in the presence of a proton gradient across the membrane. (527 aa)
sfrp2Secreted frizzled-related protein 2. (298 aa)
ednraEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (433 aa)
W5MQX3_LEPOCNeurexin 3a. (1695 aa)
W5MRF2_LEPOCGRB2-associated binding protein 1. (735 aa)
CCN3Cellular communication network factor 3. (351 aa)
aampAngio-associated, migratory cell protein. (426 aa)
igfbp2Insulin-like growth factor binding protein 2b. (280 aa)
W5MSP5_LEPOCFZ domain-containing protein. (1507 aa)
eif2ak3Eukaryotic translation initiation factor 2-alpha kinase 3. (1095 aa)
cemip2Cell migration inducing hyaluronidase 2. (1382 aa)
smarcal1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (841 aa)
W5MTX8_LEPOCFibroblast growth factor 18b; Belongs to the heparin-binding growth factors family. (99 aa)
ndnfNeuron-derived neurotrophic factor. (571 aa)
LOC102687572T-cell acute lymphocytic leukemia 1. (330 aa)
prok2Prokineticin 2. (107 aa)
W5MV98_LEPOCSi:ch211-247j9.1. (634 aa)
HIF1AHypoxia inducible factor 1 subunit alpha. (419 aa)
prkxProtein kinase X-linked. (362 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
PDCL3Phosducin like 3. (237 aa)
krit1KRIT1 ankyrin repeat containing. (742 aa)
VASH1Vasohibin 1. (361 aa)
W5MXD5_LEPOCCollagen, type XV, alpha 1b. (1213 aa)
reckReversion-inducing-cysteine-rich protein with kazal motifs. (920 aa)
plxdc2Plexin domain containing 2. (532 aa)
W5MYV5_LEPOCNeuropilin; Belongs to the neuropilin family. (912 aa)
C1GALT1Glycoprotein-N-acetylgalactosamine 3-beta-galactosyltransferase 1; Glycosyltransferase that generates the core 1 O-glycan Gal- beta1-3GalNAc-alpha1-Ser/Thr (T antigen), which is a precursor for many extended O-glycans in glycoproteins; Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily. (381 aa)
efnb2Ephrin-B2a; Belongs to the ephrin family. (337 aa)
pdgfrbPlatelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1079 aa)
W5MZC6_LEPOCThrombospondin, type I, domain containing 7Ab. (1618 aa)
jmjd6Jumonji domain containing 6, arginine demethylase and lysine hydroxylase. (403 aa)
sirt1Sirtuin 1. (720 aa)
meox2Mesenchyme homeobox 2a. (303 aa)
otulinOTU deubiquitinase with linear linkage specificity b. (415 aa)
klf5Kruppel-like factor 5b. (422 aa)
wars1Tryptophanyl-tRNA synthetase; Belongs to the class-I aminoacyl-tRNA synthetase family. (480 aa)
prok1Prokineticin 1. (106 aa)
enpepAminopeptidase. (956 aa)
W5N1S7_LEPOCSi:dkey-167k11.5. (239 aa)
ccbe1Collagen and calcium binding EGF domains 1. (392 aa)
esm1Endothelial cell-specific molecule 1. (234 aa)
flt4Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1391 aa)
arhgap24Rho GTPase activating protein 24. (750 aa)
EPGNEpithelial mitogen. (159 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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