STRINGSTRING
sfrp2 sfrp2 W5LWY2_LEPOC W5LWY2_LEPOC tgfbr2 tgfbr2 sall4 sall4 zmpste24 zmpste24 LOC102689055 LOC102689055 ccn1 ccn1 cntrl cntrl dctn5 dctn5 ARNT ARNT W5MIF3_LEPOC W5MIF3_LEPOC nsd2 nsd2 tbx5 tbx5 nprl3 nprl3 W5MM76_LEPOC W5MM76_LEPOC cpe cpe ednra ednra mstn mstn TMEM65 TMEM65 nkx2-5 nkx2-5 zfpm2 zfpm2 hectd1 hectd1 W5MUB5_LEPOC W5MUB5_LEPOC bmpr2 bmpr2 ptcd2 ptcd2 LOC102695460 LOC102695460 fgf8 fgf8 sav1 sav1 HAND1 HAND1 med1 med1 arnt2 arnt2 W5N5D9_LEPOC W5N5D9_LEPOC trip11 trip11 LOC102688510 LOC102688510 smad6 smad6 W5N9Y4_LEPOC W5N9Y4_LEPOC LOC102695900 LOC102695900 ptk7 ptk7 sema3c sema3c prdm1 prdm1 hace1 hace1 W5NIY6_LEPOC W5NIY6_LEPOC gja5 gja5 NPY5R NPY5R npy2r npy2r LOC102698548 LOC102698548
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
sfrp2Secreted frizzled-related protein 2. (298 aa)
W5LWY2_LEPOCUncharacterized protein. (822 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)
sall4Spalt-like transcription factor 4. (1092 aa)
zmpste24CAAX prenyl protease; Proteolytically removes the C-terminal three residues of farnesylated proteins; Belongs to the peptidase M48A family. (466 aa)
LOC102689055PR domain containing 1b, with ZNF domain. (774 aa)
ccn1Cellular communication network factor 1. (377 aa)
cntrlUncharacterized protein. (905 aa)
dctn5Dynactin 5. (182 aa)
ARNTAryl hydrocarbon receptor nuclear translocator. (587 aa)
W5MIF3_LEPOCMothers against decapentaplegic homolog. (556 aa)
nsd2Nuclear receptor binding SET domain protein 2. (1380 aa)
tbx5T-box transcription factor 5a. (522 aa)
nprl3NPR3-like, GATOR1 complex subunit. (594 aa)
W5MM76_LEPOCUncharacterized protein. (307 aa)
cpeCarboxypeptidase E. (463 aa)
ednraEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (433 aa)
mstnMyostatin b. (374 aa)
TMEM65Transmembrane protein 65. (262 aa)
nkx2-5NK2 homeobox 5. (315 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1148 aa)
hectd1HECT domain containing 1. (2561 aa)
W5MUB5_LEPOCTroponin I type 1a (skeletal, slow). (190 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1075 aa)
ptcd2Pentatricopeptide repeat domain 2. (384 aa)
LOC102695460Uncharacterized protein. (450 aa)
fgf8Fibroblast growth factor 8 b; Belongs to the heparin-binding growth factors family. (124 aa)
sav1Salvador family WW domain containing protein 1. (399 aa)
HAND1Heart and neural crest derivatives expressed 1. (191 aa)
med1Mediator of RNA polymerase II transcription subunit 1; Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene- specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. (1734 aa)
arnt2Aryl-hydrocarbon receptor nuclear translocator 2. (749 aa)
W5N5D9_LEPOCMothers against decapentaplegic homolog. (547 aa)
trip11Thyroid hormone receptor interactor 11. (1973 aa)
LOC102688510Troponin C type 1a (slow). (161 aa)
smad6Mothers against decapentaplegic homolog. (487 aa)
W5N9Y4_LEPOCTransforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
LOC102695900Troponin C type 1b (slow). (162 aa)
ptk7Protein tyrosine kinase 7a; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1074 aa)
sema3cSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (759 aa)
prdm1PR domain containing 1a, with ZNF domain. (816 aa)
hace1HECT domain and ankyrin repeat containing E3 ubiquitin protein ligase 1. (949 aa)
W5NIY6_LEPOCGrowth regulating estrogen receptor binding 1. (1937 aa)
gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (357 aa)
NPY5RNeuropeptide Y receptor Y5. (440 aa)
npy2rNeuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (379 aa)
LOC102698548Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family. (378 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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