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| | rad51 | DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (341 aa) |
| | wrnip1 | WRN helicase interacting protein 1. (612 aa) |
| | mcm7 | DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa) |
| | LOC102695737 | DNA helicase; Belongs to the MCM family. (834 aa) |
| | exd2 | Exonuclease 3'-5' domain containing 2. (613 aa) |
| | W5N7S3_LEPOC | Polymerase (DNA directed), gamma 2, accessory subunit. (415 aa) |
| | cdc6 | Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa) |
| | mcm2 | DNA helicase; Belongs to the MCM family. (887 aa) |
| | atrx | ATRX chromatin remodeler, like. (2427 aa) |
| | primpol | Primase and polymerase (DNA-directed). (575 aa) |
| | W5N8N6_LEPOC | ATPase family AAA domain containing 5a. (1812 aa) |
| | W5N8X8_LEPOC | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (323 aa) |
| | blm | BLM RecQ like helicase. (1481 aa) |
| | polg | Polymerase (DNA directed), gamma. (1200 aa) |
| | W5LXJ3_LEPOC | DNA_pol_B domain-containing protein. (97 aa) |
| | mcm6 | DNA helicase; Belongs to the MCM family. (819 aa) |
| | rfc4 | Replication factor C (activator 1) 4. (359 aa) |
| | rfc2 | Replication factor C (activator 1) 2. (358 aa) |
| | gins2 | DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa) |
| | orc4 | Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa) |
| | rfwd3 | Ring finger and WD repeat domain 3. (727 aa) |
| | W5M0N9_LEPOC | Zinc finger, RAN-binding domain containing 3. (1142 aa) |
| | W5M103_LEPOC | DNA ligase. (1030 aa) |
| | cdc45 | CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa) |
| | W5M196_LEPOC | WD repeat domain 18. (433 aa) |
| | pola1 | DNA polymerase. (1486 aa) |
| | GEN1 | GEN1 Holliday junction 5' flap endonuclease. (461 aa) |
| | mms22l | MMS22-like, DNA repair protein. (1238 aa) |
| | prim2 | DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (512 aa) |
| | W5NJX2_LEPOC | Origin recognition complex, subunit 3. (728 aa) |
| | gins1 | GINS complex subunit 1 (Psf1 homolog). (196 aa) |
| | helb | Helicase (DNA) B. (1126 aa) |
| | gins4 | DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa) |
| | W5NG96_LEPOC | DNA helicase; Belongs to the MCM family. (815 aa) |
| | mcm10 | Minichromosome maintenance 10 replication initiation factor. (867 aa) |
| | mgme1 | Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (344 aa) |
| | W5NF63_LEPOC | F-box DNA helicase 1. (1007 aa) |
| | W5NEJ3_LEPOC | Origin recognition complex, subunit 5. (375 aa) |
| | W5NE81_LEPOC | ATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (636 aa) |
| | pold2 | Polymerase (DNA directed), delta 2, regulatory subunit. (469 aa) |
| | lig3 | DNA ligase. (1001 aa) |
| | thoc1 | THO complex 1. (656 aa) |
| | W5M2K0_LEPOC | Polymerase (DNA directed) nu. (728 aa) |
| | EME2 | Essential meiotic structure-specific endonuclease subunit 2. (472 aa) |
| | pold3 | Polymerase (DNA-directed), delta 3, accessory subunit. (473 aa) |
| | pole3 | Polymerase (DNA directed), epsilon 3 (p17 subunit). (148 aa) |
| | W5M4G9_LEPOC | DNA_pol_E_B domain-containing protein. (66 aa) |
| | W5M4I8_LEPOC | Uncharacterized protein. (168 aa) |
| | rpain | RPA interacting protein. (227 aa) |
| | rfc5 | Replication factor C (activator 1) 5. (367 aa) |
| | gins3 | GINS complex subunit 3. (211 aa) |
| | pole4 | Polymerase (DNA-directed), epsilon 4, accessory subunit; Core component of nucleosome. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellular machineries which require DNA as a template. Histones thereby play a central role in transcription regulation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regulated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. (135 aa) |
| | pole | DNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2298 aa) |
| | timeless | Timeless circadian clock. (1225 aa) |
| | W5MA42_LEPOC | SAM domain and HD domain 1. (617 aa) |
| | W5MA78_LEPOC | HD domain-containing protein. (411 aa) |
| | gmnn | Geminin DNA replication inhibitor. (223 aa) |
| | W5MBI2_LEPOC | Chromatin licensing and DNA replication factor 1. (614 aa) |
| | ZNF830 | Zinc finger protein 830. (352 aa) |
| | orc6 | Origin recognition complex, subunit 6. (256 aa) |
| | zpr1 | ZPR1 zinc finger. (447 aa) |
| | W5MET7_LEPOC | Polymerase (DNA directed), theta. (2592 aa) |
| | tonsl | Tonsoku-like, DNA repair protein. (1444 aa) |
| | noc3l | Nucleolar complex protein 3 homolog. (805 aa) |
| | mcm4 | DNA helicase; Belongs to the MCM family. (678 aa) |
| | orc1 | Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (919 aa) |
| | ccne2 | Cyclin E2; Belongs to the cyclin family. (395 aa) |
| | rpa1 | Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa) |
| | prim1 | DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa) |
| | ddx23 | DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (818 aa) |
| | recql4 | RecQ helicase-like 4. (1459 aa) |
| | mre11 | Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (725 aa) |
| | atr | ATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2649 aa) |
| | W5MNK3_LEPOC | Tower domain-containing protein. (871 aa) |
| | rfc3 | Replication factor C (activator 1) 3. (356 aa) |
| | W5MPK4_LEPOC | TIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (151 aa) |
| | ddx21 | DEAD (Asp-Glu-Ala-Asp) box helicase 21. (777 aa) |
| | DNA2 | DNA replication helicase/nuclease 2. (1397 aa) |
| | gmnc | Geminin coiled-coil domain containing. (346 aa) |
| | BAZ1A | Bromodomain adjacent to zinc finger domain 1A. (1505 aa) |
| | smarcal1 | SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (841 aa) |
| | W5MXW8_LEPOC | WRN RecQ like helicase. (1464 aa) |
| | traip | TRAF-interacting protein. (458 aa) |
| | DONSON | Downstream neighbor of SON. (619 aa) |
| | LOC102698683 | SET domain and mariner transposase fusion gene. (296 aa) |
| | eme1 | Essential meiotic structure-specific endonuclease 1. (590 aa) |
| | FANCM | FA complementation group M. (2093 aa) |
| | pole2 | DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (527 aa) |
| | W5N0A7_LEPOC | Minichromosome maintenance complex binding protein. (638 aa) |
| | recql5 | RecQ helicase-like 5. (1025 aa) |
| | topbp1 | DNA topoisomerase II binding protein 1. (1514 aa) |
| | W5N2L8_LEPOC | WD repeat and HMG-box DNA binding protein 1. (1133 aa) |
| | LOC102697986 | DNA helicase; Belongs to the MCM family. (814 aa) |
| | sirt7 | Sirtuin 7. (437 aa) |
| | W5N4H5_LEPOC | Uncharacterized protein. (49 aa) |
| | twnk | Twinkle mtDNA helicase. (699 aa) |
