STRINGSTRING
mcm6 mcm6 mcm2 mcm2 blm blm W5NE81_LEPOC W5NE81_LEPOC W5NG96_LEPOC W5NG96_LEPOC gins4 gins4 W5MXW8_LEPOC W5MXW8_LEPOC gins2 gins2 recql5 recql5 LOC102697986 LOC102697986 twnk twnk cdc45 cdc45 gins3 gins3 rad51 rad51 mcm4 mcm4 rpa1 rpa1 recql4 recql4 mcm7 mcm7 LOC102695737 LOC102695737
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
blmBLM RecQ like helicase. (1481 aa)
W5NE81_LEPOCATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (636 aa)
W5NG96_LEPOCDNA helicase; Belongs to the MCM family. (815 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (225 aa)
W5MXW8_LEPOCWRN RecQ like helicase. (1464 aa)
gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (186 aa)
recql5RecQ helicase-like 5. (1025 aa)
LOC102697986DNA helicase; Belongs to the MCM family. (814 aa)
twnkTwinkle mtDNA helicase. (699 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
gins3GINS complex subunit 3. (211 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (341 aa)
mcm4DNA helicase; Belongs to the MCM family. (678 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (607 aa)
recql4RecQ helicase-like 4. (1459 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa)
LOC102695737DNA helicase; Belongs to the MCM family. (834 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.