STRINGSTRING
mcm2 mcm2 prim2 prim2 W5NJX2_LEPOC W5NJX2_LEPOC W5NG96_LEPOC W5NG96_LEPOC mcm10 mcm10 W5NEJ3_LEPOC W5NEJ3_LEPOC cdc6 cdc6 LOC102695737 LOC102695737 mcm7 mcm7 LOC102697986 LOC102697986 topbp1 topbp1 gmnc gmnc prim1 prim1 ccne2 ccne2 orc1 orc1 mcm4 mcm4 noc3l noc3l orc6 orc6 gins3 gins3 W5M4I8_LEPOC W5M4I8_LEPOC W5M4G9_LEPOC W5M4G9_LEPOC pola1 pola1 cdc45 cdc45 orc4 orc4 mcm6 mcm6
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
mcm2DNA helicase; Belongs to the MCM family. (887 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (512 aa)
W5NJX2_LEPOCOrigin recognition complex, subunit 3. (728 aa)
W5NG96_LEPOCDNA helicase; Belongs to the MCM family. (815 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (867 aa)
W5NEJ3_LEPOCOrigin recognition complex, subunit 5. (375 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (558 aa)
LOC102695737DNA helicase; Belongs to the MCM family. (834 aa)
mcm7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (721 aa)
LOC102697986DNA helicase; Belongs to the MCM family. (814 aa)
topbp1DNA topoisomerase II binding protein 1. (1514 aa)
gmncGeminin coiled-coil domain containing. (346 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (426 aa)
ccne2Cyclin E2; Belongs to the cyclin family. (395 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (919 aa)
mcm4DNA helicase; Belongs to the MCM family. (678 aa)
noc3lNucleolar complex protein 3 homolog. (805 aa)
orc6Origin recognition complex, subunit 6. (256 aa)
gins3GINS complex subunit 3. (211 aa)
W5M4I8_LEPOCUncharacterized protein. (168 aa)
W5M4G9_LEPOCDNA_pol_E_B domain-containing protein. (66 aa)
pola1DNA polymerase. (1486 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (570 aa)
orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (434 aa)
mcm6DNA helicase; Belongs to the MCM family. (819 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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