STRINGSTRING
LOC102694198 LOC102694198 W5MZR6_LEPOC W5MZR6_LEPOC srpk1 srpk1 luc7l3 luc7l3 fastkd2 fastkd2 ddx20 ddx20 dhx30 dhx30 dhx29 dhx29 puf60 puf60 gemin8 gemin8 W5MV15_LEPOC W5MV15_LEPOC shq1 shq1 W5MUL8_LEPOC W5MUL8_LEPOC EIF3A EIF3A xrcc5 xrcc5 gemin2 gemin2 polr2d polr2d sf3a1 sf3a1 W5MND4_LEPOC W5MND4_LEPOC W5MNA9_LEPOC W5MNA9_LEPOC nudt21 nudt21 NAF1 NAF1 luc7l luc7l eif6 eif6 rpl6 rpl6 W5MKV1_LEPOC W5MKV1_LEPOC ruvbl2 ruvbl2 W5NH47_LEPOC W5NH47_LEPOC snrpf snrpf celf2 celf2 snrpg snrpg rpl10 rpl10 SRPK2 SRPK2 strap strap mcts1 mcts1 cdc73 cdc73 LOC102686698 LOC102686698 ythdc1 ythdc1 eif3e eif3e W5M5N8_LEPOC W5M5N8_LEPOC prmt7 prmt7 sf3a3 sf3a3 eif3h eif3h eral1 eral1 eif2s3 eif2s3 LOC102692574 LOC102692574 W5M7L2_LEPOC W5M7L2_LEPOC sf3b1 sf3b1 trnau1ap trnau1ap eif3b eif3b SETX SETX mrto4 mrto4 eif3m eif3m W5MB44_LEPOC W5MB44_LEPOC sart3 sart3 W5MBJ5_LEPOC W5MBJ5_LEPOC prpf6 prpf6 lsm2 lsm2 ZNHIT6 ZNHIT6 prpf8 prpf8 LOC102685476 LOC102685476 denr denr W5ME38_LEPOC W5ME38_LEPOC NUFIP1 NUFIP1 traf7 traf7 rpl23a rpl23a EIF3I EIF3I sf3a2 sf3a2 celf1 celf1 W5MG32_LEPOC W5MG32_LEPOC W5MGI3_LEPOC W5MGI3_LEPOC W5MGT5_LEPOC W5MGT5_LEPOC W5M2C1_LEPOC W5M2C1_LEPOC lsm4 lsm4 snrpd1 snrpd1 pih1d2 pih1d2 W5LZS2_LEPOC W5LZS2_LEPOC eif3f eif3f eif4h eif4h nle1 nle1 LOC102683561 LOC102683561 clns1a clns1a W5MI85_LEPOC W5MI85_LEPOC gemin4 gemin4 W5MIU7_LEPOC W5MIU7_LEPOC LOC102693848 LOC102693848 W5LXF3_LEPOC W5LXF3_LEPOC LOC102693418 LOC102693418 W5LWY8_LEPOC W5LWY8_LEPOC LOC107076457 LOC107076457 W5LVC6_LEPOC W5LVC6_LEPOC W5LVC1_LEPOC W5LVC1_LEPOC prpf31 prpf31 eif3g eif3g W5MKE7_LEPOC W5MKE7_LEPOC nop2 nop2 W5MJA1_LEPOC W5MJA1_LEPOC W5NI19_LEPOC W5NI19_LEPOC eif3l eif3l LOC102683569 LOC102683569 rrs1 rrs1 gemin7 gemin7 ddx28 ddx28 W5NLW8_LEPOC W5NLW8_LEPOC rpf2 rpf2 crnkl1 crnkl1 prpf18 prpf18 snrpd3 snrpd3 usp39 usp39 snrnp200 snrnp200 celf6 celf6 clg8h12orf45 clg8h12orf45 snrpd2 snrpd2 W5NC84_LEPOC W5NC84_LEPOC SRPK3 SRPK3 W5NBB0_LEPOC W5NBB0_LEPOC mrps11 mrps11 ruvbl1 ruvbl1 eif3k eif3k nop53 nop53 isy1 isy1 W5N8S8_LEPOC W5N8S8_LEPOC eif3j eif3j W5N879_LEPOC W5N879_LEPOC mrps7 mrps7 W5N6H4_LEPOC W5N6H4_LEPOC W5N5R3_LEPOC W5N5R3_LEPOC RAMAC RAMAC W5N595_LEPOC W5N595_LEPOC W5N4R3_LEPOC W5N4R3_LEPOC W5N3R6_LEPOC W5N3R6_LEPOC eif2d eif2d rpsa rpsa rrp7a rrp7a LOC102689485 LOC102689485 snrpe snrpe PSIP1 PSIP1 brix1 brix1 W5N049_LEPOC W5N049_LEPOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC102694198Survival of motor neuron 1, telomeric. (279 aa)
W5MZR6_LEPOCPRP39 pre-mRNA processing factor 39 homolog (yeast). (668 aa)
srpk1SRSF protein kinase 1b. (658 aa)
luc7l3LUC7-like 3 pre-mRNA splicing factor. (456 aa)
fastkd2RAP domain-containing protein. (690 aa)
ddx20DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (786 aa)
dhx30DEAH (Asp-Glu-Ala-His) box helicase 30. (1167 aa)
dhx29ATP-dependent RNA helicase DHX29; ATP-binding RNA helicase involved in translation initiation. Part of the 43S pre-initiation complex that is required for efficient initiation on mRNAs of higher eukaryotes with structured 5'-UTRs by promoting efficient NTPase-dependent 48S complex formation. Specifically binds to the 40S ribosome near the mRNA entrance. Does not possess a processive helicase activity; Belongs to the DEAD box helicase family. DEAH subfamily. (1377 aa)
puf60Poly-U binding splicing factor b. (527 aa)
gemin8Gem (nuclear organelle) associated protein 8. (230 aa)
W5MV15_LEPOCUncharacterized protein. (84 aa)
shq1SHQ1, H/ACA ribonucleoprotein assembly factor. (626 aa)
W5MUL8_LEPOCEukaryotic translation initiation factor 5. (431 aa)
EIF3AEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1264 aa)
xrcc5X-ray repair cross-complementing protein 5; Single-stranded DNA-dependent ATP-dependent helicase. Belongs to the ku80 family. (727 aa)
gemin2Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (264 aa)
polr2dPolymerase (RNA) II (DNA directed) polypeptide D. (144 aa)
sf3a1Splicing factor 3a, subunit 1. (791 aa)
W5MND4_LEPOCRibonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
W5MNA9_LEPOCPre-mRNA processing factor 19. (465 aa)
nudt21Cleavage and polyadenylation specificity factor subunit 5; Component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. CFIm contributes to the recruitment of multiprotein complexes on specific sequences on the pre-mRNA 3'-end, so called cleavage and polyadenylation signals (pA signals). Most pre-mRNAs contain multiple pA signals, resulting in alternative cleavage and polyadenylation (APA) producing mRNAs with variable 3'-end formation. The [...] (228 aa)
NAF1Nuclear assembly factor 1 ribonucleoprotein. (400 aa)
luc7lLUC7-like (S. cerevisiae). (373 aa)
eif6Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (245 aa)
rpl6Ribosomal protein L6. (264 aa)
W5MKV1_LEPOCZinc finger (CCCH type), RNA-binding motif and serine/arginine rich 2. (525 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (463 aa)
W5NH47_LEPOCCleavage and polyadenylation specific factor 6. (583 aa)
snrpfSmall nuclear ribonucleoprotein polypeptide F. (86 aa)
celf2Cugbp, Elav-like family member 2. (523 aa)
snrpgSmall nuclear ribonucleoprotein G. (76 aa)
rpl10Ribosomal protein L10. (215 aa)
SRPK2SRSF protein kinase 2. (570 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
mcts1Malignant T-cell-amplified sequence. (181 aa)
cdc73Cell division cycle 73, Paf1/RNA polymerase II complex component, homolog (S. cerevisiae). (531 aa)
LOC102686698Small nuclear ribonucleoprotein-associated protein. (238 aa)
ythdc1YTH domain containing 1. (765 aa)
eif3eEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (446 aa)
W5M5N8_LEPOCZinc finger, HIT-type containing 3. (154 aa)
prmt7Protein arginine N-methyltransferase; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA), with a preference for the formation of MMA. Specifically mediates the symmetrical dimethylation of arginine residues in the small nuclear ribonucleoproteins Sm D1 (SNRPD1) and Sm D3 (SNRPD3); such methylation being required for the assembly and biogenesis of snRNP core particles. Specifically mediates the symmetric dimethylation of histone H4 'Arg-3' to form H4R3me2s. Plays a role in gene imprinting by being r [...] (702 aa)
sf3a3Splicing factor 3a, subunit 3. (501 aa)
eif3hEukaryotic translation initiation factor 3 subunit H; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (347 aa)
eral1Era-like 12S mitochondrial rRNA chaperone 1. (467 aa)
eif2s3Eukaryotic translation initiation factor 2, subunit 3 gamma. (472 aa)
LOC10269257440S ribosomal protein S27. (84 aa)
W5M7L2_LEPOCPWP2 small subunit processome component. (923 aa)
sf3b1Splicing factor 3b, subunit 1. (1317 aa)
trnau1aptRNA selenocysteine 1 associated protein 1a. (295 aa)
eif3bEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (682 aa)
SETXSenataxin. (2398 aa)
mrto4Ribosome assembly factor mrt4; Component of the ribosome assembly machinery. Nuclear paralog of the ribosomal protein P0, it binds pre-60S subunits at an early stage of assembly in the nucleolus, and is replaced by P0 in cytoplasmic pre-60S subunits and mature 80S ribosomes. (246 aa)
eif3mEukaryotic translation initiation factor 3 subunit M; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (375 aa)
W5MB44_LEPOCRibosomal protein L5b. (354 aa)
sart3Spliceosome associated factor 3, U4/U6 recycling protein. (992 aa)
W5MBJ5_LEPOCCUGBP, Elav-like family member 4. (411 aa)
prpf6PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (995 aa)
lsm2U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (95 aa)
ZNHIT6Zinc finger HIT-type containing 6. (299 aa)
prpf8Pre-mRNA processing factor 8. (2338 aa)
LOC102685476Cugbp, Elav-like family member 5a. (547 aa)
denrDensity-regulated protein; Belongs to the DENR family. (197 aa)
W5ME38_LEPOCEukaryotic translation initiation factor 4Ba. (615 aa)
NUFIP1Nuclear FMR1 interacting protein 1. (514 aa)
traf7TNF receptor-associated factor 7. (675 aa)
rpl23aRibosomal protein L23a; Belongs to the universal ribosomal protein uL23 family. (170 aa)
EIF3IEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (323 aa)
sf3a2Splicing factor 3a, subunit 2. (310 aa)
celf1Cugbp, Elav-like family member 1. (534 aa)
W5MG32_LEPOCProtein kinase, DNA-activated, catalytic subunit; Belongs to the PI3/PI4-kinase family. (4160 aa)
W5MGI3_LEPOCSplicing factor SWAP. (963 aa)
W5MGT5_LEPOCKH domain containing 4, pre-mRNA splicing factor. (582 aa)
W5M2C1_LEPOCDEAH (Asp-Glu-Ala-His) box helicase 9. (1268 aa)
lsm4U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (141 aa)
snrpd1Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (117 aa)
pih1d2PIH1 domain containing 2. (319 aa)
W5LZS2_LEPOCMitochondrial rRNA methyltransferase 2. (242 aa)
eif3fEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (288 aa)
eif4hEukaryotic translation initiation factor 4h. (261 aa)
nle1Notchless homolog 1 (Drosophila). (477 aa)
LOC102683561Cugbp, Elav-like family member 3b. (383 aa)
clns1aChloride channel, nucleotide-sensitive, 1A. (244 aa)
W5MI85_LEPOC40S ribosomal protein S27. (102 aa)
gemin4Gem (nuclear organelle) associated protein 4. (1075 aa)
W5MIU7_LEPOCDRBM domain-containing protein. (85 aa)
LOC102693848Tudor domain-containing protein. (303 aa)
W5LXF3_LEPOCRibosomal_S7 domain-containing protein. (142 aa)
LOC102693418Protein argonaute-4; Required for RNA-mediated gene silencing (RNAi). Binds to short RNAs such as microRNAs (miRNAs) and represses the translation of mRNAs which are complementary to them. Lacks endonuclease activity and does not appear to cleave target mRNAs; Belongs to the argonaute family. Ago subfamily. (873 aa)
W5LWY8_LEPOCPRMT5_TIM domain-containing protein. (133 aa)
LOC107076457Uncharacterized protein. (171 aa)
W5LVC6_LEPOCUncharacterized protein. (138 aa)
W5LVC1_LEPOCUncharacterized protein. (168 aa)
prpf31PRP31 pre-mRNA processing factor 31 homolog (yeast). (509 aa)
eif3gEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (300 aa)
W5MKE7_LEPOCProstaglandin E synthase 3b (cytosolic). (146 aa)
nop2NOP2 nucleolar protein homolog (yeast); Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family. (546 aa)
W5MJA1_LEPOCXPA binding protein 2. (845 aa)
W5NI19_LEPOCSR-related CTD-associated factor 11. (1368 aa)
eif3lEukaryotic translation initiation factor 3 subunit L; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (588 aa)
LOC102683569Ribonucloprotein; Common component of the spliceosome and rRNA processing machinery; Belongs to the eukaryotic ribosomal protein eL8 family. (128 aa)
rrs1Ribosome biogenesis regulatory protein; Involved in ribosomal large subunit assembly. Belongs to the RRS1 family. (342 aa)
gemin7Gem (nuclear organelle) associated protein 7. (122 aa)
ddx28DEAD (Asp-Glu-Ala-Asp) box polypeptide 28. (558 aa)
W5NLW8_LEPOCRRM domain-containing protein. (92 aa)
rpf2Ribosome production factor 2 homolog. (308 aa)
crnkl1Crooked neck pre-mRNA splicing factor 1. (725 aa)
prpf18PRP18 pre-mRNA processing factor 18 homolog (yeast). (351 aa)
snrpd3Small nuclear ribonucleoprotein Sm D3. (127 aa)
usp39Ubiquitin specific peptidase 39. (498 aa)
snrnp200Small nuclear ribonucleoprotein 200 (U5). (2138 aa)
celf6Si:dkey-205h23.2. (380 aa)
clg8h12orf45Si:dkey-48p11.3. (140 aa)
snrpd2Small nuclear ribonucleoprotein Sm D2. (118 aa)
W5NC84_LEPOC40S ribosomal protein S27. (82 aa)
SRPK3SRSF protein kinase 3. (319 aa)
W5NBB0_LEPOCActivator of basal transcription 1. (270 aa)
mrps11Mitochondrial ribosomal protein S11; Belongs to the universal ribosomal protein uS11 family. (203 aa)
ruvbl1RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (270 aa)
eif3kEukaryotic translation initiation factor 3 subunit K; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (205 aa)
nop53Ribosome biogenesis protein NOP53; May play a role in ribosome biogenesis. Belongs to the NOP53 family. (452 aa)
isy1ISY1 splicing factor homolog. (319 aa)
W5N8S8_LEPOCCoilin p80. (376 aa)
eif3jEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (252 aa)
W5N879_LEPOCSi:ch211-220i18.4. (591 aa)
mrps7Mitochondrial ribosomal protein S7. (229 aa)
W5N6H4_LEPOCtRNA selenocysteine 1 associated protein 1b. (311 aa)
W5N5R3_LEPOCUncharacterized protein. (626 aa)
RAMACRNA guanine-7 methyltransferase activating subunit. (125 aa)
W5N595_LEPOCRibosomal protein L38; Belongs to the eukaryotic ribosomal protein eL38 family. (70 aa)
W5N4R3_LEPOCSPATA6 domain-containing protein. (397 aa)
W5N3R6_LEPOCGem (nuclear organelle) associated protein 5. (1460 aa)
eif2dEukaryotic translation initiation factor 2D. (595 aa)
rpsa40S ribosomal protein SA; Required for the assembly and/or stability of the 40S ribosomal subunit. Required for the processing of the 20S rRNA- precursor to mature 18S rRNA in a late step of the maturation of 40S ribosomal subunits. Also functions as a cell surface receptor for laminin. Plays a role in cell adhesion to the basement membrane and in the consequent activation of signaling transduction pathways. May play a role in cell fate determination and tissue morphogenesis. Belongs to the universal ribosomal protein uS2 family. (308 aa)
rrp7aRRM_Rrp7 domain-containing protein. (75 aa)
LOC102689485Uncharacterized protein. (317 aa)
snrpeSmall nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
PSIP1PC4 and SFRS1 interacting protein 1. (519 aa)
brix1Brix domain containing 2. (346 aa)
W5N049_LEPOCUncharacterized protein. (121 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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