(25 nodes) Negative regulation of I-kappaB kinase/NF-kappaB signaling network (Lepisosteus oculatus)

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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textmining

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protein homology

Your Input:
	W5MRP9_LEPOC	OTU deubiquitinase 7B. (930 aa)
	TNIP3	TNFAIP3 interacting protein 3. (324 aa)
	ppm1a	Protein phosphatase, Mg2+/Mn2+ dependent, 1Aa. (383 aa)
	LOC102686811	Uncharacterized protein. (512 aa)
	CASP8	Caspase 8; Belongs to the peptidase C14A family. (543 aa)
	W5MXT6_LEPOC	Caspase 8; Belongs to the peptidase C14A family. (552 aa)
	LOC102697829	Uncharacterized protein; Belongs to the peptidase C14A family. (474 aa)
	sirt1	Sirtuin 1. (720 aa)
	tnip1	TNFAIP3 interacting protein 1. (651 aa)
	zmynd11	Zinc finger, MYND-type containing 11. (626 aa)
	OTUD7A	OTU deubiquitinase 7A. (937 aa)
	LOC102689167	Protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative). (421 aa)
	nr1h4	Nuclear receptor subfamily 1, group H, member 4. (486 aa)
	W5NEC4_LEPOC	Tumor necrosis factor, alpha-induced protein 3. (776 aa)
	ppm1b	Protein phosphatase, Mg2+/Mn2+ dependent, 1Bb. (403 aa)
	tank	TRAF family member-associated NFKB activator. (317 aa)
	LOC102691632	Adiponectin, C1Q and collagen domain containing, b. (266 aa)
	ash1l	BAH domain-containing protein. (175 aa)
	W5MGK5_LEPOC	Nuclear receptor subfamily 1, group D, member 4b. (362 aa)
	chuk	Component of inhibitor of nuclear factor kappa B kinase complex. (763 aa)
	usp10	Ubiquitin carboxyl-terminal hydrolase. (903 aa)
	W5M8I7_LEPOC	NLR family member X1. (935 aa)
	W5M609_LEPOC	Si:dkey-206d17.12. (622 aa)
	riok3	Serine/threonine-protein kinase RIO3; Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family. (511 aa)
	W5LVE4_LEPOC	SET domain-containing protein. (117 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CASP8	LOC102697829	ENSLOCP00000013183	ENSLOCP00000013204	Caspase 8; Belongs to the peptidase C14A family.	Uncharacterized protein; Belongs to the peptidase C14A family.	0.793
CASP8	W5MXT6_LEPOC	ENSLOCP00000013183	ENSLOCP00000013195	Caspase 8; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.863
LOC102686811	sirt1	ENSLOCP00000012738	ENSLOCP00000013852	Uncharacterized protein.	Sirtuin 1.	0.437
LOC102689167	ppm1a	ENSLOCP00000018323	ENSLOCP00000012321	Protein phosphatase, Mg2+/Mn2+ dependent, 1Nb (putative).	Protein phosphatase, Mg2+/Mn2+ dependent, 1Aa.	0.859
LOC102691632	sirt1	ENSLOCP00000008517	ENSLOCP00000013852	Adiponectin, C1Q and collagen domain containing, b.	Sirtuin 1.	0.510
LOC102697829	CASP8	ENSLOCP00000013204	ENSLOCP00000013183	Uncharacterized protein; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.793
OTUD7A	TNIP3	ENSLOCP00000018227	ENSLOCP00000011981	OTU deubiquitinase 7A.	TNFAIP3 interacting protein 3.	0.628
OTUD7A	chuk	ENSLOCP00000018227	ENSLOCP00000005304	OTU deubiquitinase 7A.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.487
OTUD7A	tnip1	ENSLOCP00000018227	ENSLOCP00000014500	OTU deubiquitinase 7A.	TNFAIP3 interacting protein 1.	0.628
TNIP3	OTUD7A	ENSLOCP00000011981	ENSLOCP00000018227	TNFAIP3 interacting protein 3.	OTU deubiquitinase 7A.	0.628
TNIP3	W5MRP9_LEPOC	ENSLOCP00000011981	ENSLOCP00000011058	TNFAIP3 interacting protein 3.	OTU deubiquitinase 7B.	0.628
TNIP3	W5NEC4_LEPOC	ENSLOCP00000011981	ENSLOCP00000018983	TNFAIP3 interacting protein 3.	Tumor necrosis factor, alpha-induced protein 3.	0.961
W5LVE4_LEPOC	ash1l	ENSLOCP00000000101	ENSLOCP00000007653	SET domain-containing protein.	BAH domain-containing protein.	0.900
W5M609_LEPOC	W5NEC4_LEPOC	ENSLOCP00000003817	ENSLOCP00000018983	Si:dkey-206d17.12.	Tumor necrosis factor, alpha-induced protein 3.	0.445
W5M609_LEPOC	tank	ENSLOCP00000003817	ENSLOCP00000010467	Si:dkey-206d17.12.	TRAF family member-associated NFKB activator.	0.676
W5M8I7_LEPOC	chuk	ENSLOCP00000004695	ENSLOCP00000005304	NLR family member X1.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.626
W5MRP9_LEPOC	TNIP3	ENSLOCP00000011058	ENSLOCP00000011981	OTU deubiquitinase 7B.	TNFAIP3 interacting protein 3.	0.628
W5MRP9_LEPOC	chuk	ENSLOCP00000011058	ENSLOCP00000005304	OTU deubiquitinase 7B.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.487
W5MRP9_LEPOC	tnip1	ENSLOCP00000011058	ENSLOCP00000014500	OTU deubiquitinase 7B.	TNFAIP3 interacting protein 1.	0.628
W5MXT6_LEPOC	CASP8	ENSLOCP00000013195	ENSLOCP00000013183	Caspase 8; Belongs to the peptidase C14A family.	Caspase 8; Belongs to the peptidase C14A family.	0.863