Genes that are sometimes fused into single open reading frames.
STRING allows inspection of the interaction evidence for any given network. Choose any of the viewers above (disabled if not applicable in your network).
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes: query proteins and first shell of interactors
white nodes: second shell of interactors
Node Content
empty nodes: proteins of unknown 3D structure
filled nodes: a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
igf1r
Tyrosine-protein kinase receptor. (1180 aa)
LOC107077247
Uncharacterized protein. (125 aa)
insr
Tyrosine-protein kinase receptor. (1365 aa)
grb2
Growth factor receptor-bound protein 2b. (217 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918 Other names: L. oculatus, spotted gar