(45 nodes) Regulation of fat cell differentiation network (Lepisosteus oculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sav1	Salvador family WW domain containing protein 1. (399 aa)
	W5LYD5_LEPOC	E2F transcription factor 1. (431 aa)
	ptgs2	Prostaglandin-endoperoxide synthase 2b. (610 aa)
	bbs12	Bardet-Biedl syndrome 12. (690 aa)
	W5M5R8_LEPOC	X-box binding protein 1. (385 aa)
	W5M609_LEPOC	Si:dkey-206d17.12. (622 aa)
	W5M6S4_LEPOC	BSD domain-containing protein. (282 aa)
	ZADH2	Zinc binding alcohol dehydrogenase domain containing 2. (408 aa)
	CMKLR1	Chemokine-like receptor 1 like 2; Belongs to the G-protein coupled receptor 1 family. (291 aa)
	W5MFB9_LEPOC	DNA-damage-inducible transcript 3. (262 aa)
	W5MG31_LEPOC	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (584 aa)
	W5MHZ6_LEPOC	Tribbles pseudokinase 3. (252 aa)
	mmp11	Matrix metallopeptidase 11a. (486 aa)
	LOC102691632	Adiponectin, C1Q and collagen domain containing, b. (266 aa)
	syap1	Synapse associated protein 1. (362 aa)
	W5MM76_LEPOC	Uncharacterized protein. (307 aa)
	sfrp2	Secreted frizzled-related protein 2. (298 aa)
	zfpm2	Zinc finger protein, FOG family member 2a. (1148 aa)
	tmem64	Transmembrane protein 64. (350 aa)
	htr2a	5-hydroxytryptamine (serotonin) receptor 2A, genome duplicate a. (469 aa)
	noct	Nocturnin a. (438 aa)
	sirt1	Sirtuin 1. (720 aa)
	klf5	Kruppel-like factor 5b. (422 aa)
	rreb1	Ras responsive element binding protein 1b. (1666 aa)
	vstm2a	V-set and transmembrane domain containing 2A. (240 aa)
	LOC102694859	Coactivator-associated arginine methyltransferase 1, like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family. (463 aa)
	zfp36l1	Zinc finger protein 36, C3H type-like 1a. (358 aa)
	metrnl	Meteorin like, glial cell differentiation regulator b. (304 aa)
	W5N9Y4_LEPOC	Transforming growth factor beta; Belongs to the TGF-beta family. (392 aa)
	gata2	GATA binding protein 2a. (464 aa)
	LOC102698937	Sb:cb81. (394 aa)
	LOC102695056	Zgc:162730. (370 aa)
	LOC102690202	Kruppel-like factor 5 like. (407 aa)
	W5NFT2_LEPOC	Uncharacterized protein. (200 aa)
	W5NGC4_LEPOC	N-acyl phosphatidylethanolamine phospholipase D. (406 aa)
	PTPRQ	Protein tyrosine phosphatase receptor type Q. (2353 aa)
	W5NHN6_LEPOC	ASXL transcriptional regulator 2. (1388 aa)
	dusp10	Dual specificity phosphatase 10. (476 aa)
	zfp36l2	Uncharacterized protein. (432 aa)
	crebl2	cAMP responsive element binding protein-like 2. (119 aa)
	W5NJ49_LEPOC	Delta-like 2 homolog (Drosophila). (381 aa)
	LOC102696733	Chemerin chemokine-like receptor 1; Belongs to the G-protein coupled receptor 1 family. (350 aa)
	LOC102694387	Formyl peptide receptor 1; Belongs to the G-protein coupled receptor 1 family. (377 aa)
	cebpb	CCAAT/enhancer-binding protein. (295 aa)
	medag	Uncharacterized protein. (249 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102690202	cebpb	ENSLOCP00000018407	ENSLOCP00000022459	Kruppel-like factor 5 like.	CCAAT/enhancer-binding protein.	0.698
LOC102691632	cebpb	ENSLOCP00000008517	ENSLOCP00000022459	Adiponectin, C1Q and collagen domain containing, b.	CCAAT/enhancer-binding protein.	0.650
LOC102691632	sirt1	ENSLOCP00000008517	ENSLOCP00000013852	Adiponectin, C1Q and collagen domain containing, b.	Sirtuin 1.	0.510
LOC102694859	gata2	ENSLOCP00000015449	ENSLOCP00000017894	Coactivator-associated arginine methyltransferase 1, like; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	GATA binding protein 2a.	0.605
LOC102698937	zfp36l1	ENSLOCP00000017950	ENSLOCP00000017209	Sb:cb81.	Zinc finger protein 36, C3H type-like 1a.	0.859
LOC102698937	zfp36l2	ENSLOCP00000017950	ENSLOCP00000020311	Sb:cb81.	Uncharacterized protein.	0.722
PTPRQ	dusp10	ENSLOCP00000020116	ENSLOCP00000020246	Protein tyrosine phosphatase receptor type Q.	Dual specificity phosphatase 10.	0.456
W5LYD5_LEPOC	cebpb	ENSLOCP00000001142	ENSLOCP00000022459	E2F transcription factor 1.	CCAAT/enhancer-binding protein.	0.459
W5LYD5_LEPOC	sirt1	ENSLOCP00000001142	ENSLOCP00000013852	E2F transcription factor 1.	Sirtuin 1.	0.610
W5M5R8_LEPOC	W5MFB9_LEPOC	ENSLOCP00000003726	ENSLOCP00000007078	X-box binding protein 1.	DNA-damage-inducible transcript 3.	0.942
W5M5R8_LEPOC	cebpb	ENSLOCP00000003726	ENSLOCP00000022459	X-box binding protein 1.	CCAAT/enhancer-binding protein.	0.655
W5MFB9_LEPOC	W5M5R8_LEPOC	ENSLOCP00000007078	ENSLOCP00000003726	DNA-damage-inducible transcript 3.	X-box binding protein 1.	0.942
W5MFB9_LEPOC	W5MHZ6_LEPOC	ENSLOCP00000007078	ENSLOCP00000008005	DNA-damage-inducible transcript 3.	Tribbles pseudokinase 3.	0.670
W5MFB9_LEPOC	cebpb	ENSLOCP00000007078	ENSLOCP00000022459	DNA-damage-inducible transcript 3.	CCAAT/enhancer-binding protein.	0.881
W5MG31_LEPOC	gata2	ENSLOCP00000007340	ENSLOCP00000017894	Coactivator-associated arginine methyltransferase 1; Belongs to the class I-like SAM-binding methyltransferase superfamily. Protein arginine N-methyltransferase family.	GATA binding protein 2a.	0.605
W5MHZ6_LEPOC	W5MFB9_LEPOC	ENSLOCP00000008005	ENSLOCP00000007078	Tribbles pseudokinase 3.	DNA-damage-inducible transcript 3.	0.670
W5MHZ6_LEPOC	cebpb	ENSLOCP00000008005	ENSLOCP00000022459	Tribbles pseudokinase 3.	CCAAT/enhancer-binding protein.	0.618
cebpb	LOC102690202	ENSLOCP00000022459	ENSLOCP00000018407	CCAAT/enhancer-binding protein.	Kruppel-like factor 5 like.	0.698
cebpb	LOC102691632	ENSLOCP00000022459	ENSLOCP00000008517	CCAAT/enhancer-binding protein.	Adiponectin, C1Q and collagen domain containing, b.	0.650
cebpb	W5LYD5_LEPOC	ENSLOCP00000022459	ENSLOCP00000001142	CCAAT/enhancer-binding protein.	E2F transcription factor 1.	0.459