STRINGSTRING
W5MAJ1_LEPOC W5MAJ1_LEPOC cdh5 cdh5 rapgef3 rapgef3 DDAH1 DDAH1 C5 C5 FGF1 FGF1 utp15 utp15 sirt1 sirt1 W5N048_LEPOC W5N048_LEPOC itgb8 itgb8 il10 il10 W5N3N8_LEPOC W5N3N8_LEPOC LOC102693289 LOC102693289 CXCL8 CXCL8 CXCL8-2 CXCL8-2 vegfa vegfa W5NG76_LEPOC W5NG76_LEPOC btg1 btg1 W5NBC6_LEPOC W5NBC6_LEPOC ctsh ctsh sash1 sash1 W5NAB2_LEPOC W5NAB2_LEPOC serpine1 serpine1 LOC102695806 LOC102695806 LOC102697660 LOC102697660 tbxa2r tbxa2r DDAH2 DDAH2 ENSLOCP00000001232 ENSLOCP00000001232 igf2 igf2 LOC102686735 LOC102686735 mdk mdk W5MEM1_LEPOC W5MEM1_LEPOC W5MER1_LEPOC W5MER1_LEPOC tie1 tie1 angptl3 angptl3 W5MJ78_LEPOC W5MJ78_LEPOC W5MKA8_LEPOC W5MKA8_LEPOC W5MM29_LEPOC W5MM29_LEPOC W5MM76_LEPOC W5MM76_LEPOC sfrp2 sfrp2 W5MRF2_LEPOC W5MRF2_LEPOC JMJD8 JMJD8 aqp1 aqp1 tgfbr2 tgfbr2 TNN TNN W5M3M0_LEPOC W5M3M0_LEPOC fgf2 fgf2 hspb1 hspb1 W5M5R8_LEPOC W5M5R8_LEPOC W5M5U9_LEPOC W5M5U9_LEPOC W5M5W8_LEPOC W5M5W8_LEPOC W5M609_LEPOC W5M609_LEPOC mydgf mydgf LOC102695612 LOC102695612 W5N848_LEPOC W5N848_LEPOC adm2 adm2 W5NMF6_LEPOC W5NMF6_LEPOC W5NN97_LEPOC W5NN97_LEPOC LOC102685279 LOC102685279 W5MTX8_LEPOC W5MTX8_LEPOC
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
W5MAJ1_LEPOCChemokine (C-X-C motif) receptor 3, tandem duplicate 1; Belongs to the G-protein coupled receptor 1 family. (369 aa)
cdh5Cadherin 5; Cadherins are calcium-dependent cell adhesion proteins. (770 aa)
rapgef3Rap guanine nucleotide exchange factor (GEF) 3. (877 aa)
DDAH1Dimethylarginine dimethylaminohydrolase 1. (282 aa)
C5Complement C5. (1580 aa)
FGF1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (155 aa)
utp15UTP15 small subunit processome component. (505 aa)
sirt1Sirtuin 1. (720 aa)
W5N048_LEPOCUncharacterized protein. (1423 aa)
itgb8Integrin beta; Belongs to the integrin beta chain family. (807 aa)
il10Interleukin 10. (181 aa)
W5N3N8_LEPOCReceptor (G protein-coupled) activity modifying protein 2. (163 aa)
LOC102693289Si:ch73-380n15.2. (510 aa)
CXCL8Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (143 aa)
CXCL8-2Interleukin-8; Belongs to the intercrine alpha (chemokine CxC) family. (104 aa)
vegfaVascular endothelial growth factor Ab; Belongs to the PDGF/VEGF growth factor family. (253 aa)
W5NG76_LEPOCElastin microfibril interfacer 1b. (969 aa)
btg1B-cell translocation gene 1, anti-proliferative. (174 aa)
W5NBC6_LEPOCCholinergic receptor, nicotinic, alpha 7 (neuronal). (486 aa)
ctshCathepsin H; Belongs to the peptidase C1 family. (331 aa)
sash1SAM and SH3 domain containing 1b. (1196 aa)
W5NAB2_LEPOCUncharacterized protein. (116 aa)
serpine1Serpin peptidase inhibitor, clade E (nexin, plasminogen activator inhibitor type 1), member 1; Belongs to the serpin family. (391 aa)
LOC102695806Junction plakoglobin b. (738 aa)
LOC102697660TNFR-Cys domain-containing protein. (208 aa)
tbxa2rThromboxane A2 receptor. (346 aa)
DDAH2Dimethylarginine dimethylaminohydrolase 2. (274 aa)
ENSLOCP00000001232annotation not available (208 aa)
igf2Insulin-like growth factor 2b. (217 aa)
LOC102686735Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (208 aa)
mdkMidkine b. (145 aa)
W5MEM1_LEPOCSp1 transcription factor. (691 aa)
W5MER1_LEPOCAngiogenic factor with G patch and FHA domains 1. (713 aa)
tie1Tyrosine kinase with immunoglobulin-like and EGF-like domains 1. (1137 aa)
angptl3Angiopoietin-like 3. (466 aa)
W5MJ78_LEPOCNuclear factor, erythroid 2-like 2a. (616 aa)
W5MKA8_LEPOCUncharacterized protein. (172 aa)
W5MM29_LEPOCVascular endothelial growth factor D; Belongs to the PDGF/VEGF growth factor family. (311 aa)
W5MM76_LEPOCUncharacterized protein. (307 aa)
sfrp2Secreted frizzled-related protein 2. (298 aa)
W5MRF2_LEPOCGRB2-associated binding protein 1. (735 aa)
JMJD8Jumonji domain containing 8. (207 aa)
aqp1Aquaporin 1a (Colton blood group), tandem duplicate 1; Belongs to the MIP/aquaporin (TC 1.A.8) family. (262 aa)
tgfbr2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (557 aa)
TNNTenascin N. (1320 aa)
W5M3M0_LEPOCBMP binding endothelial regulator. (644 aa)
fgf2Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (167 aa)
hspb1Heat shock protein, alpha-crystallin-related, 1; Belongs to the small heat shock protein (HSP20) family. (207 aa)
W5M5R8_LEPOCX-box binding protein 1. (385 aa)
W5M5U9_LEPOCTEK tyrosine kinase, endothelial. (1116 aa)
W5M5W8_LEPOCHeat shock protein, alpha-crystallin-related, b15; Belongs to the small heat shock protein (HSP20) family. (225 aa)
W5M609_LEPOCSi:dkey-206d17.12. (622 aa)
mydgfMyeloid-derived growth factor. (164 aa)
LOC102695612Cytochrome P450, family 1, subfamily B, polypeptide 1; Belongs to the cytochrome P450 family. (534 aa)
W5N848_LEPOCVascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (441 aa)
adm2Adrenomedullin 2b. (170 aa)
W5NMF6_LEPOCCytochrome P450, family 1, subfamily C, polypeptide 2; Belongs to the cytochrome P450 family. (528 aa)
W5NN97_LEPOCLRRCT domain-containing protein. (337 aa)
LOC102685279Apelin receptor a; Belongs to the G-protein coupled receptor 1 family. (359 aa)
W5MTX8_LEPOCFibroblast growth factor 18b; Belongs to the heparin-binding growth factors family. (99 aa)
Your Current Organism:
Lepisosteus oculatus
NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar
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