(66 nodes) Spindle assembly network (Lepisosteus oculatus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC107076317	CLASP_N domain-containing protein. (257 aa)
	LOC102682992	Si:ch1073-416j23.1. (648 aa)
	poldip2	Polymerase (DNA-directed), delta interacting protein 2. (375 aa)
	W5LZG9_LEPOC	V-myb avian myeloblastosis viral oncogene homolog-like 2b. (659 aa)
	lsm14a	LSM14A mRNA processing body assembly factor b. (481 aa)
	CLASP1	Cytoplasmic linker associated protein 1a. (1608 aa)
	haus3	HAUS augmin-like complex, subunit 3. (625 aa)
	clasp2	Cytoplasmic linker associated protein 2. (1515 aa)
	W5M553_LEPOC	Spindle and centriole associated protein 1. (578 aa)
	haus5	HAUS augmin-like complex, subunit 5. (651 aa)
	rcc1	Regulator of chromosome condensation 1. (421 aa)
	chek2	Checkpoint kinase 2. (518 aa)
	W5M8B8_LEPOC	Uncharacterized protein. (326 aa)
	W5M9Z9_LEPOC	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (836 aa)
	racgap1	Rac GTPase activating protein 1. (654 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (760 aa)
	cep63	CEP63 domain-containing protein. (720 aa)
	wrap73	WD repeat containing, antisense to TP73. (449 aa)
	aaas	Achalasia, adrenocortical insufficiency, alacrimia. (520 aa)
	mapre1	Microtubule-associated protein, RP/EB family, member 1a. (315 aa)
	W5MEP5_LEPOC	Uncharacterized protein. (354 aa)
	W5MER6_LEPOC	Si:zfos-452g4.1. (328 aa)
	W5MG98_LEPOC	TPX2 microtubule nucleation factor. (725 aa)
	mapre2	Microtubule-associated protein, RP/EB family, member 2. (331 aa)
	aurka	Aurora kinase A; Belongs to the protein kinase superfamily. (337 aa)
	W5MJ86_LEPOC	Uncharacterized protein. (727 aa)
	kif11	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1063 aa)
	bccip	Protein BCCIP homolog; Belongs to the BCP1 family. (316 aa)
	NUMA1	Nuclear mitotic apparatus protein 1. (2302 aa)
	abraxas2	Abraxas 2, BRISC complex subunit. (444 aa)
	tubgcp5	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (1014 aa)
	W5MNM2_LEPOC	Uncharacterized protein. (230 aa)
	W5MNV4_LEPOC	Microtubule-associated protein 9. (637 aa)
	stil	STIL centriolar assembly protein. (1307 aa)
	tubgcp3	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (901 aa)
	W5MTK4_LEPOC	Centrosomal protein 192. (2478 aa)
	haus1	HAUS augmin-like complex, subunit 1. (286 aa)
	TOGARAM1	TOG array regulator of axonemal microtubules 1. (1519 aa)
	MZT1	Mitotic spindle organizing protein 1. (81 aa)
	pibf1	Progesterone immunomodulatory binding factor 1. (759 aa)
	W5N0Z4_LEPOC	HAUS6_N domain-containing protein. (823 aa)
	haus2	Si:dkey-170l10.1. (202 aa)
	CCDC69	Coiled-coil domain containing 69. (314 aa)
	W5N316_LEPOC	Uncharacterized protein. (222 aa)
	csnk1d	Casein kinase 1, delta b; Belongs to the protein kinase superfamily. (408 aa)
	ino80	INO80 complex ATPase subunit. (1554 aa)
	smc3	Structural maintenance of chromosomes protein. (1217 aa)
	lzts2	Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (681 aa)
	aurkb	Aurora kinase B; Belongs to the protein kinase superfamily. (337 aa)
	W5N736_LEPOC	Transcription activation suppressor a. (1524 aa)
	znf207	Zinc finger protein 207, a. (496 aa)
	kpnb1	Karyopherin (importin) beta 1. (878 aa)
	kif4a	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1246 aa)
	kif23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (977 aa)
	prc1	Protein regulator of cytokinesis 1a. (610 aa)
	tubgcp4	Gamma-tubulin complex component; Gamma-tubulin complex is necessary for microtubule nucleation at the centrosome; Belongs to the TUBGCP family. (668 aa)
	ccdc61	Coiled-coil domain containing 61. (532 aa)
	W5NEG7_LEPOC	Adaptor protein, phosphotyrosine interaction, PH domain and leucine zipper containing 2. (1621 aa)
	fbxo5	F-box protein 5. (394 aa)
	haus7	HAUS augmin-like complex, subunit 7. (384 aa)
	W5NFV3_LEPOC	Si:ch1073-266p11.2. (801 aa)
	mapre3	Microtubule-associated protein, RP/EB family, member 3b. (323 aa)
	nek2	NIMA-related kinase 2. (437 aa)
	W5NM73_LEPOC	Uncharacterized protein. (146 aa)
	LOC102690992	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (378 aa)
	LOC102696230	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (375 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CLASP1	W5MEP5_LEPOC	ENSLOCP00000002460	ENSLOCP00000006854	Cytoplasmic linker associated protein 1a.	Uncharacterized protein.	0.485
CLASP1	W5N0Z4_LEPOC	ENSLOCP00000002460	ENSLOCP00000014303	Cytoplasmic linker associated protein 1a.	HAUS6_N domain-containing protein.	0.491
CLASP1	haus1	ENSLOCP00000002460	ENSLOCP00000013723	Cytoplasmic linker associated protein 1a.	HAUS augmin-like complex, subunit 1.	0.444
CLASP1	mapre1	ENSLOCP00000002460	ENSLOCP00000006810	Cytoplasmic linker associated protein 1a.	Microtubule-associated protein, RP/EB family, member 1a.	0.644
CLASP1	mapre2	ENSLOCP00000002460	ENSLOCP00000007415	Cytoplasmic linker associated protein 1a.	Microtubule-associated protein, RP/EB family, member 2.	0.435
CLASP1	mapre3	ENSLOCP00000002460	ENSLOCP00000020134	Cytoplasmic linker associated protein 1a.	Microtubule-associated protein, RP/EB family, member 3b.	0.435
LOC102682992	W5MG98_LEPOC	ENSLOCP00000000809	ENSLOCP00000007407	Si:ch1073-416j23.1.	TPX2 microtubule nucleation factor.	0.542
LOC102682992	W5MJ86_LEPOC	ENSLOCP00000000809	ENSLOCP00000008445	Si:ch1073-416j23.1.	Uncharacterized protein.	0.786
LOC102682992	W5N316_LEPOC	ENSLOCP00000000809	ENSLOCP00000015025	Si:ch1073-416j23.1.	Uncharacterized protein.	0.840
LOC102682992	aurka	ENSLOCP00000000809	ENSLOCP00000007654	Si:ch1073-416j23.1.	Aurora kinase A; Belongs to the protein kinase superfamily.	0.639
LOC102682992	aurkb	ENSLOCP00000000809	ENSLOCP00000016433	Si:ch1073-416j23.1.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.639
LOC102682992	kif11	ENSLOCP00000000809	ENSLOCP00000008576	Si:ch1073-416j23.1.	Kinesin family member 11; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.943
LOC102682992	kif23	ENSLOCP00000000809	ENSLOCP00000017258	Si:ch1073-416j23.1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.996
LOC102682992	kif4a	ENSLOCP00000000809	ENSLOCP00000017056	Si:ch1073-416j23.1.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.795
LOC102682992	nek2	ENSLOCP00000000809	ENSLOCP00000020196	Si:ch1073-416j23.1.	NIMA-related kinase 2.	0.458
LOC102682992	prc1	ENSLOCP00000000809	ENSLOCP00000017412	Si:ch1073-416j23.1.	Protein regulator of cytokinesis 1a.	0.888
LOC102682992	racgap1	ENSLOCP00000000809	ENSLOCP00000005658	Si:ch1073-416j23.1.	Rac GTPase activating protein 1.	0.556
LOC102690992	LOC102696230	ENSLOCP00000021832	ENSLOCP00000021994	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.702
LOC102696230	LOC102690992	ENSLOCP00000021994	ENSLOCP00000021832	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family.	0.702
LOC107076317	W5MEP5_LEPOC	ENSLOCP00000000366	ENSLOCP00000006854	CLASP_N domain-containing protein.	Uncharacterized protein.	0.485