(12 nodes) Spindle midzone assembly network (Lepisosteus oculatus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	CCDC69	Coiled-coil domain containing 69. (314 aa)
	LOC102682992	Si:ch1073-416j23.1. (648 aa)
	racgap1	Rac GTPase activating protein 1. (654 aa)
	mlh1	MutL homolog 1, colon cancer, nonpolyposis type 2 (E. coli). (760 aa)
	W5MJ86_LEPOC	Uncharacterized protein. (727 aa)
	W5N316_LEPOC	Uncharacterized protein. (222 aa)
	lzts2	Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (681 aa)
	aurkb	Aurora kinase B; Belongs to the protein kinase superfamily. (337 aa)
	kif4a	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1246 aa)
	kif23	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (977 aa)
	prc1	Protein regulator of cytokinesis 1a. (610 aa)
	W5NFV3_LEPOC	Si:ch1073-266p11.2. (801 aa)

Your Current Organism:

Lepisosteus oculatus

NCBI taxonomy Id: 7918
Other names: L. oculatus, spotted gar

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102682992	W5MJ86_LEPOC	ENSLOCP00000000809	ENSLOCP00000008445	Si:ch1073-416j23.1.	Uncharacterized protein.	0.786
LOC102682992	W5N316_LEPOC	ENSLOCP00000000809	ENSLOCP00000015025	Si:ch1073-416j23.1.	Uncharacterized protein.	0.840
LOC102682992	aurkb	ENSLOCP00000000809	ENSLOCP00000016433	Si:ch1073-416j23.1.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.639
LOC102682992	kif23	ENSLOCP00000000809	ENSLOCP00000017258	Si:ch1073-416j23.1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.996
LOC102682992	kif4a	ENSLOCP00000000809	ENSLOCP00000017056	Si:ch1073-416j23.1.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.795
LOC102682992	prc1	ENSLOCP00000000809	ENSLOCP00000017412	Si:ch1073-416j23.1.	Protein regulator of cytokinesis 1a.	0.888
LOC102682992	racgap1	ENSLOCP00000000809	ENSLOCP00000005658	Si:ch1073-416j23.1.	Rac GTPase activating protein 1.	0.556
W5MJ86_LEPOC	LOC102682992	ENSLOCP00000008445	ENSLOCP00000000809	Uncharacterized protein.	Si:ch1073-416j23.1.	0.786
W5MJ86_LEPOC	W5N316_LEPOC	ENSLOCP00000008445	ENSLOCP00000015025	Uncharacterized protein.	Uncharacterized protein.	0.802
W5MJ86_LEPOC	aurkb	ENSLOCP00000008445	ENSLOCP00000016433	Uncharacterized protein.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.996
W5MJ86_LEPOC	kif23	ENSLOCP00000008445	ENSLOCP00000017258	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.947
W5MJ86_LEPOC	kif4a	ENSLOCP00000008445	ENSLOCP00000017056	Uncharacterized protein.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.612
W5MJ86_LEPOC	prc1	ENSLOCP00000008445	ENSLOCP00000017412	Uncharacterized protein.	Protein regulator of cytokinesis 1a.	0.863
W5MJ86_LEPOC	racgap1	ENSLOCP00000008445	ENSLOCP00000005658	Uncharacterized protein.	Rac GTPase activating protein 1.	0.786
W5N316_LEPOC	LOC102682992	ENSLOCP00000015025	ENSLOCP00000000809	Uncharacterized protein.	Si:ch1073-416j23.1.	0.840
W5N316_LEPOC	W5MJ86_LEPOC	ENSLOCP00000015025	ENSLOCP00000008445	Uncharacterized protein.	Uncharacterized protein.	0.802
W5N316_LEPOC	aurkb	ENSLOCP00000015025	ENSLOCP00000016433	Uncharacterized protein.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.706
W5N316_LEPOC	kif23	ENSLOCP00000015025	ENSLOCP00000017258	Uncharacterized protein.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.909
W5N316_LEPOC	kif4a	ENSLOCP00000015025	ENSLOCP00000017056	Uncharacterized protein.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.830
W5N316_LEPOC	racgap1	ENSLOCP00000015025	ENSLOCP00000005658	Uncharacterized protein.	Rac GTPase activating protein 1.	0.840